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Progress in the molecular analysis of human genetic disease has been very rapid over the last three years since the first edition of this book was published. Most of the genes involved in the more common monogenic disorders have been identified and many of the rarer disorders have now been mapped to chromosomal regions. This thoroughly updated edition discusses these developments in detail. The techniques available for gene mapping have changed substantially thus facilitating isolation of disease genes from their chromosomal positions. Animal models are being created to allow the detailed study of disease processes. The second edition fully covers these advancements and should be a valuable reference for students, clinicians, and researchers in the biological sciences.
Chromosome mapping --- Genetic disorders --- Chromosome Mapping --- Genetic Diseases, Inborn --- Genetic Markers --- genetics --- etiology --- Chromosome mapping. --- Genetic disorders. --- Molecular genetics. --- Chromosome Mapping. --- Genetic Markers. --- Hereditary Diseases --- genetics. --- Genetics. --- Genetic Diseases, Inborn - genetics --- Genetic Diseases, Inborn - etiology
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The application of new gene technology has made the study of inherited diseases at the molecular level one of today's fastest moving research areas. This textbook reviews the latest breakthroughs and concentrates on the different types of mutation and their analysis by both classical methods and the newest DNA mapping techniques. Students will find here the information they need to complement lecture courses.
Human genetics --- Molecular biology --- Human gene mapping --- Genetic disorders --- Genetic Diseases, Inborn --- Genetic Markers --- Chromosome Mapping --- genetics --- etiology --- Chromosome Mapping. --- Genetic Markers. --- 577.27 --- Molecular genetics --- #ABIB:aimm --- Genetics --- Human chromosome mapping --- Human genome mapping --- Mapping, Human gene --- Gene mapping --- Congenital diseases --- Disorders, Genetic --- Disorders, Inherited --- Genetic diseases --- Hereditary diseases --- Inherited diseases --- Diseases --- Medical genetics --- Genetic Marker --- Marker, Genetic --- Chromosome Markers --- DNA Markers --- Markers, DNA --- Markers, Genetic --- Chromosome Marker --- DNA Marker --- Marker, Chromosome --- Marker, DNA --- Markers, Chromosome --- Random Amplified Polymorphic DNA Technique --- Genome Mapping --- Gene Mapping --- Linkage Mapping --- Chromosome Mappings --- Gene Mappings --- Genome Mappings --- Linkage Mappings --- Mapping, Chromosome --- Mapping, Gene --- Mapping, Genome --- Mapping, Linkage --- Mappings, Chromosome --- Mappings, Gene --- Mappings, Genome --- Mappings, Linkage --- Cytogenetics --- Cytogenetic Analysis --- Gene Order --- Synteny --- etiology. --- genetics. --- Molecular bases of immunity. Molecular immunology --- Genetic disorders. --- Human gene mapping. --- Molecular genetics. --- Genetic Marker. --- Hereditary Diseases --- 577.27 Molecular bases of immunity. Molecular immunology --- Etiology. --- Genetic Diseases, Inborn - genetics --- Genetic Diseases, Inborn - etiology
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