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Since the initial establishment of Robert Koch’s postulates in the nineteenth century, microbial protein toxins have been recognized as a major factor of bacterial and fungal virulence. An increasing number of proteins produced and secreted by various bacteria, yeasts and plants are extremely toxic and most of them developed remarkably "intelligent" strategies to enter, to penetrate and to finally kill a eukaryotic target cell by modifying or blocking essential cellular components. This book describes the strategies employed by protein toxins to render their pro- and eukaryotic producers a selective growth advantage over competitors. In providing an up-to-date overview on the mode of protein toxin actions, it accommodates biomedically and biologically relevant toxin model systems. As a result, it significantly broadens our perspective on biochemical architecture and molecular ploy behind the lethal principles of pro- and eukaryotic toxins.

Microbial toxins. --- Toxins. --- Toxines --- Microbial toxins --- Toxins --- Fungal Proteins --- Mycotoxins --- Bacterial Toxins --- Bacterial Proteins --- Toxins, Biological --- Proteins --- Amino Acids, Peptides, and Proteins --- Biological Factors --- Chemicals and Drugs --- Animal Biochemistry --- Microbiology & Immunology --- Human Anatomy & Physiology --- Biology --- Health & Biological Sciences --- Biologic Agents --- Biologic Factors --- Biological Factor --- Factor, Biologic --- Factor, Biological --- Factors, Biological --- Biological Agents --- Agents, Biologic --- Agents, Biological --- Biologic Factor --- Factors, Biologic --- Gene Products, Protein --- Gene Proteins --- Protein Gene Products --- Proteins, Gene --- Natural toxicants --- Toxicants, Natural --- Toxins and antitoxins --- Biological Toxins --- Bacterial Gene Product --- Bacterial Gene Protein --- Bacterial Protein --- Gene Product, Bacterial --- Gene Protein, Bacterial --- Gene Proteins, Bacterial --- Protein, Bacterial --- Proteins, Bacterial --- Bacterial Gene Products --- Bacterial Gene Proteins --- Gene Products, Bacterial --- Toxins, Bacterial --- Fungal Toxins --- Toxins, Fungal --- Fungal Gene Products --- Fungal Gene Proteins --- Fungal Peptides --- Gene Products, Fungal --- Yeast Proteins --- Gene Proteins, Fungal --- Peptides, Fungal --- Proteins, Fungal --- Life sciences. --- Medical microbiology. --- Biochemistry. --- Cell biology. --- Microbiology. --- Life Sciences. --- Medical Microbiology. --- Biochemistry, general. --- Cell Biology. --- Microbial biology --- Microorganisms --- Cell biology --- Cellular biology --- Cells --- Cytologists --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Chemistry --- Medical sciences --- Biosciences --- Sciences, Life --- Science --- Composition --- Cytology.