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Cancer --- Genetic aspects. --- Radiotherapy. --- Cancer genetics --- Cancer genes --- Treatment --- Càncer --- Micro RNAs. --- Genètica mèdica

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The study of transcriptomics is key to understanding complex diseases. This new edition will build on the foundation of the first edition while incorporating the progress that has been made in the field of transcriptomics in the past six years, including bioinformatics for data analysis. Written by leading experts, chapters address new subjects such as methodological advances in large-scale sequencing, the sequencing of single-cells, and spatial transcriptomics. The new edition will address how transcriptomics may be used in combination with genetic strategies to identify causative genes in monogenic and complex genetic diseases. Coverage will also explore transcriptomics in challenging groups of diseases, such as cancer, inflammation, bacterial infection, and autoimmune diseases. The updated volume will be useful for geneticists, genome biologists, biomedical researchers, molecular biologists, bioinformaticians, and students, among others.

Biomathematics. Biometry. Biostatistics --- Genetics --- Molecular biology --- bio-informatica --- genetica --- moleculaire biologie --- Gene expression. --- RNA --- Genètica mèdica

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"An international journal of genetics in medicine."

Medical genetics --- Genetics, Medical --- Genetics, Medical. --- Génétique médicale --- Medical genetics. --- Medische genetica. --- Human Genetics --- Medical Genetics --- Genetics, Human --- Clinical genetics --- Diseases --- Heredity of disease --- Genetic aspects --- Anthropology, Physical --- Chromosome Disorders --- Sex Chromosome Disorders --- Genetic Diseases, Inborn --- Molecular Medicine --- Human genetics --- Medical sciences --- Pathology --- Genetic disorders --- Genètica mèdica --- Genètica clínica --- Malalties --- Ciències de la salut --- Genètica humana --- Malalties congènites --- Patologia --- Aspectes genètics

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This extensive volume began as a short course primarily geared toward toxicologists who want to expand their understanding of toxicologic pathology in order to be better study directors while also proving to be of great interest to other drug development scientists and regulatory reviewers. The overall goal is to help non-pathologists understand, contextualize, and communicate the pathology data and interpretations from the study pathologist in a practical and usable format. Within the book, readers will find an overview of general pathology concepts that include fundamental vocabulary and the basics of pathophysiological processes, along with numerous chapters devoted to pathology in specific organ systems as well as topics such as biomarkers, correlation of clinical pathology endpoints (chemistry and hematology) with microscopic changes, and well-known pathology findings for classes of toxic substances. Authoritative, practical, and comprehensive, Toxicologic Pathology for Non-Pathologists aims to help non-pathologists understand, converse in, and apply a basic understanding of pathology in their day-to-day careers.

Toxicology. --- Chemicals --- Medicine --- Pharmacology --- Poisoning --- Poisons --- Toxicology --- Pharmacology. --- Pathology. --- Pharmacology/Toxicology. --- Disease (Pathology) --- Medical sciences --- Diseases --- Medicine, Preventive --- Drug effects --- Medical pharmacology --- Chemotherapy --- Drugs --- Pharmacy --- Physiological effect --- Patologia --- Patologia humana --- Medicina --- Bacteriologia --- Càlculs --- Degeneració (Patologia) --- Diagnòstic de laboratori --- Estenosi --- Etiologia --- Genètica mèdica --- Glucòlisi --- Hipertròfia --- Histopatologia --- Hèrnia --- Immunopatologia --- Inflamació --- Insuficiència sistèmica --- Malformacions --- Metàstasi --- Paleopatologia --- Patologia cel·lular --- Patologia veterinària --- Teratologia --- Tumors --- Xoc --- Anatomia patològica --- Diagnòstic

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This book reviews normal thymic structure and covers the histomorphology of benign and malignant tumors and rare lesions of the thymus, with detailed descriptions of over 300 full color photomicrographs accompanied by relevant clinical and radiology photographs and anatomical drawings. It includes chapters on the surgical pathology and cytology of thymic lesions (which is rarely described in the available literature), and all grades and stages of the most common thymic lesions. Written and edited by leading experts on pathology, the book highlights the expanded role of pathologists in patient care for thymic lesions. It will help students to understand thymic cytology and surgical pathology in detail and enable them to answer questions on thymic surgical resections and cytology cases in their pathology post-graduation examination. In addition, the book offers a comprehensive, richly illustrated guide to thymic pathology for clinicians, practicing pathologists, post-graduate residents and students alike.

Pathology. --- Disease (Pathology) --- Medical sciences --- Diseases --- Medicine --- Medicine, Preventive --- Thymus --- Tumors --- Thymus gland --- Endocrine glands --- Lymphoid tissue --- Quistos --- Patologia --- 650 --- Patologia humana --- Medicina --- Bacteriologia --- Càlculs --- Degeneració (Patologia) --- Diagnòstic de laboratori --- Estenosi --- Etiologia --- Genètica mèdica --- Glucòlisi --- Hipertròfia --- Histopatologia --- Hèrnia --- Immunopatologia --- Inflamació --- Insuficiència sistèmica --- Malformacions --- Metàstasi --- Paleopatologia --- Patologia cel·lular --- Patologia veterinària --- Teratologia --- Xoc --- Anatomia patològica --- Diagnòstic --- Colesteatoma --- Equinococcosi