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Dramatic advances in computing power enable simulation of DNA sequences generated by complex microevolutionary scenarios that include mutation, population structure, natural selection, meiotic recombination, demographic change, and explicit spatial geographies. Although retrospective, coalescent simulation is computationally efficient-and covered here-the primary focus of this book is forward-in-time simulation, which frees us to simulate a wider variety of realistic microevolutionary models. The book walks the reader through the development of a forward-in-time evolutionary simulator dubbed FORward Time simUlatioN Application (FORTUNA). The capacity of FORTUNA grows with each chapter through the addition of a new evolutionary factor to its code. Each chapter also reviews the relevant theory and links simulation results to key evolutionary insights. The book addresses visualization of results through development of R code and reference to more than 100 figures. All code discussed in the book is freely available, which the reader may use directly or modify to better suit his or her own research needs. Advanced undergraduate students, graduate students, and professional researchers will all benefit from this introduction to the increasingly important skill of population genetic simulation. .

Nature protection --- Biomathematics. Biometry. Biostatistics --- Biological techniques --- Evolution. Phylogeny --- Plant genetics. Plant evolution --- landschapsecologie --- bio-informatica --- biologie --- Europees recht --- evolutieleer --- planten --- Population genetics --- Genètica de poblacions --- Genètica evolutiva.

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This concise, entry level text provides an introduction to the importance of genetic studies in conservation and presents the essentials of the discipline in an easy-to-follow format, with main points and terms clearly highlighted. The authors assume only a basic knowledge of Mendelian genetics and simple statistics, making the book accessible to those with a limited background in these areas. Connections between conservation genetics and the wider field of conservation biology are interwoven throughout the book. Worked examples are provided throughout to help illustrate key equations and glossary and suggestions for further reading provide additional support for the reader. Many beautiful pen and ink portraits of endangered species are included to enhance the text. Written for short, introductory level courses in genetics, conservation genetics and conservation biology, this book will also be suitable for practising conservation biologists, zoo biologists and wildlife managers.

575 --- 575 General genetics. General cytogenetics. Immunogenetics. Evolution. Speciation. Phylogeny --- General genetics. General cytogenetics. Immunogenetics. Evolution. Speciation. Phylogeny --- Biodiversity --- Conservation biology --- Ecological genetics --- Evolutionary genetics --- Genetics --- #WPLT:ecol --- Biology --- Embryology --- Mendel's law --- Adaptation (Biology) --- Breeding --- Chromosomes --- Heredity --- Mutation (Biology) --- Variation (Biology) --- Genetic evolution --- Evolution (Biology) --- Ecology --- Nature conservation --- Biological diversification --- Biological diversity --- Biotic diversity --- Diversification, Biological --- Diversity, Biological --- Biocomplexity --- Ecological heterogeneity --- Numbers of species --- Ecological genetics. --- Genetics. --- Conservation biology. --- Biodiversity. --- Evolutionary genetics. --- Biological diversity. --- Biologia de la conservació. --- Biodiversitat. --- Genètica evolutiva. --- Evolució (Biologia) --- Genètica --- Diversitat biològica --- Diversitat ecològica --- Biologia --- Heterogeneïtat ecològica --- Conservació de recursos (Biologia) --- Ecologia --- Natura --- Protecció

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This fully updated book collects numerous data mining techniques, reflecting the acceleration and diversity of the development of data-driven approaches to the life sciences. The first half of the volume examines genomics, particularly metagenomics and epigenomics, which promise to deepen our knowledge of genes and genomes, while the second half of the book emphasizes metabolism and the metabolome as well as relevant medicine-oriented subjects. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of detail and expert implementation advice that is useful for getting optimal results. Authoritative and practical, Data Mining for Systems Biology: Methods and Protocols, Second Edition serves as an ideal resource for researchers of biology and relevant fields, such as medical, pharmaceutical, and agricultural sciences, as well as for the scientists and engineers who are working on developing data-driven techniques, such as databases, data sciences, data mining, visualization systems, and machine learning or artificial intelligence that now are central to the paradigm-altering discoveries being made with a higher frequency.

Bioinformatics. --- Bio-informatics --- Biological informatics --- Biology --- Information science --- Computational biology --- Systems biology --- Data processing --- Mineria de dades --- Genètica --- Bioinformàtica --- Informàtica biològica --- Ciències de la informació --- Biologia computacional --- Biologia --- Lleis de Mendel --- Al·lelomorfisme --- Cariotips --- Citogenètica --- Epigènesi --- Epigenètica --- Farmacogenètica --- Fenotip --- Genètica animal --- Genètica de poblacions --- Genètica de la conducta --- Genètica del desenvolupament --- Genètica evolutiva --- Genètica forense --- Genètica humana --- Genètica microbiana --- Genètica molecular --- Genètica quantitativa --- Genètica vegetal --- Herència citoplasmàtica --- Herència i medi --- Immunogenètica --- Neurogenètica --- Recursos genètics --- Selecció natural --- Sexualitat --- Adaptació (Biologia) --- Cromosomes --- Evolució --- Herència (Biologia) --- Millora de les espècies --- Mutació (Biologia) --- Nutrigenòmica --- Variació (Biologia) --- Prospecció de dades --- Cerca en bases de dades --- Arquitectura orientada a serveis (Informàtica) --- Extracció de dades de llocs web --- Mineria de web

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Genetics --- Study and teaching. --- Biology --- Embryology --- Mendel's law --- Adaptation (Biology) --- Breeding --- Chromosomes --- Heredity --- Mutation (Biology) --- Variation (Biology) --- Genètica --- Ensenyament científic --- Educació secundària --- Segon ensenyament --- Etapes educatives --- Batxillerat --- Educació secundària obligatòria --- Educació secundària postobligatòria --- Ensenyament nocturn --- Lectura (Educació secundària) --- Escoles secundàries --- Educació científica --- Ensenyament de la ciència --- Ensenyament --- Ensenyament de la química --- Educació STEM --- Biologia --- Lleis de Mendel --- Al·lelomorfisme --- Cariotips --- Citogenètica --- Epigènesi --- Epigenètica --- Farmacogenètica --- Fenotip --- Genètica animal --- Genètica de poblacions --- Genètica de la conducta --- Genètica del desenvolupament --- Genètica evolutiva --- Genètica forense --- Genètica humana --- Genètica microbiana --- Genètica molecular --- Genètica quantitativa --- Genètica vegetal --- Herència citoplasmàtica --- Herència i medi --- Immunogenètica --- Neurogenètica --- Recursos genètics --- Selecció natural --- Sexualitat --- Adaptació (Biologia) --- Cromosomes --- Evolució --- Herència (Biologia) --- Millora de les espècies --- Mutació (Biologia) --- Nutrigenòmica --- Variació (Biologia)

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Neoplasms --- Cancer --- genetics --- Genetic aspects --- Periodicals --- Aspect génétique --- Périodiques --- genetics. --- Genetic aspects. --- Cancer genetics --- Cancers --- Carcinoma --- Malignancy (Cancer) --- Malignant tumors --- Benign Neoplasms --- Malignancy --- Neoplasia --- Neoplasm --- Neoplasms, Benign --- Tumors --- Benign Neoplasm --- Malignancies --- Neoplasias --- Neoplasm, Benign --- Tumor --- cancer genetics --- Cancer genes --- Malignant Neoplasms --- Malignant Neoplasm --- Neoplasm, Malignant --- Neoplasms, Malignant --- Medical Oncology --- Oncology. --- Genetics --- Oncology. Neoplasms --- Càncer. --- Genètica. --- Biologia --- Lleis de Mendel --- Al·lelomorfisme --- Cariotips --- Citogenètica --- Epigènesi --- Epigenètica --- Farmacogenètica --- Fenotip --- Genètica animal --- Genètica de poblacions --- Genètica de la conducta --- Genètica del desenvolupament --- Genètica evolutiva --- Genètica forense --- Genètica humana --- Genètica microbiana --- Genètica molecular --- Genètica quantitativa --- Genètica vegetal --- Herència citoplasmàtica --- Herència i medi --- Immunogenètica --- Neurogenètica --- Recursos genètics --- Selecció natural --- Sexualitat --- Adaptació (Biologia) --- Cromosomes --- Evolució --- Herència (Biologia) --- Millora de les espècies --- Mutació (Biologia) --- Nutrigenòmica --- Variació (Biologia) --- Carcinosi --- Càncer d'ossos --- Càncer de cap --- Càncer de coll --- Càncer de bufeta --- Càncer de fetge --- Càncer de laringe --- Càncer de mama --- Càncer de pàncrees --- Càncer de pell --- Càncer de pròstata --- Càncer de pulmó --- Càncer de ronyó --- Càncer de tiroide --- Càncer d'ovari --- Càncer gastrointestinal --- Càncer ginecològic --- Càncer en els adolescents --- Càncer en els infants --- Medicaments antineoplàstics --- Melanoma --- Leucèmia --- Sarcoma --- Carcinògens --- Cèl·lules canceroses --- Cirurgia oncològica --- Infermeria oncològica --- Malalts de càncer --- Metàstasi --- Oncologia