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Ypt/Rab GTPases form the largest branch of the Ras-related small GTPase superfamily and regulate intracellular membrane trafficking in all eukaryotes. This e-book is the first ever volume focused on the Ypt/Rab GTPases and should provide a useful resource for researchers, students and teachers interested in the field.

Guanosine triphosphate. --- GTPase-activating protein. --- Cell membranes. --- Membrane proteins. --- Membrane lipids. --- Biological transport.

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For the first time experts in the area of signalling research with a focus on the ARF family have contributed to the production of a title devoted to ARF biology. A comprehensive phylogenetic analysis of the ARF family, tables of the ARF GEFs and ARF GAPs, and more than a dozen chapters describing them in detail are provided. The impact of the ARF proteins on widely diverse aspects of cell biology and cell signalling can be clearly seen from the activities described; including membrane traffic, lipid metabolism, receptor desensitization, mouse development, microtubule dynamics, and bacterial pathogenesis. Anyone interested in understanding the complexities of cell signalling and the integration of signalling networks will benefit from this volume.

Guanosine triphosphatase. --- GTPase-activating protein. --- ADP-ribosylation. --- Biochemistry. --- Evolution (Biology). --- Biochemistry, general. --- Evolutionary Biology. --- Evolutionary biology. --- Animal evolution --- Animals --- Biological evolution --- Darwinism --- Evolutionary biology --- Evolutionary science --- Origin of species --- Biology --- Evolution --- Biological fitness --- Homoplasy --- Natural selection --- Phylogeny --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Chemistry --- Medical sciences --- Composition --- Cellular signal transduction --- GAP (Protein) --- Proteins --- GTP phosphohydrolase --- GTPase --- Guanosine triphosphate phosphohydrolase --- Guanosinetriphosphatase --- Phosphatases

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“Symmetry Breaking in Cells and Tissues” presents a collection of seventeen reviews, opinions and original research papers contributed by theoreticians, physicists and mathematicians, as well as experimental biologists, united by a common interest in biological pattern formation and morphogenesis. The contributors discuss diverse manifestations of symmetry breaking in biology and showcase recent developments in experimental and theoretical approaches to biological morphogenesis and pattern formation on multiple scales.

Research & information: general --- Biology, life sciences --- actin waves --- curved proteins --- dynamic instability --- podosomes --- diffusion --- cell polarity --- Cdc42 --- stress --- cellular memory --- phase separation --- prions --- apoptotic extrusion --- oncogenic extrusion --- contractility --- actomyosin --- bottom-up synthetic biology --- motor proteins --- pattern formation --- self-organization --- cell motility --- signal transduction --- actin dynamics --- intracellular waves --- polarization --- direction sensing --- symmetry-breaking --- biphasic responses --- reaction-diffusion --- membrane and cortical tension --- cell fusion --- cortexillin --- cytokinesis --- Dictyostelium --- myosin --- symmetry breaking --- cytoplasmic flow --- phase-space analysis --- nonlinear waves --- actin polymerization --- bifurcation theory --- mass conservation --- spatial localization --- activator–inhibitor models --- developmental transitions --- cell polarization --- mathematical model --- fission yeast --- reaction–diffusion model --- small GTPases --- Cdc42 oscillations --- pseudopod --- Ras activation --- cytoskeleton --- chemotaxis --- neutrophils --- natural variation --- modelling --- activator-substrate mechanism --- mass-conserved models --- intracellular polarization --- partial differential equations --- sensitivity analysis --- GTPase activating protein (GAP) --- fission yeast Schizosaccharomyces pombe --- CRY2-CIBN --- optogenetics --- clustering --- positive feedback --- network evolution --- Saccharomyces cerevisiae --- polarity --- modularity --- neutrality --- n/a

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• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

“Symmetry Breaking in Cells and Tissues” presents a collection of seventeen reviews, opinions and original research papers contributed by theoreticians, physicists and mathematicians, as well as experimental biologists, united by a common interest in biological pattern formation and morphogenesis. The contributors discuss diverse manifestations of symmetry breaking in biology and showcase recent developments in experimental and theoretical approaches to biological morphogenesis and pattern formation on multiple scales.

Research & information: general --- Biology, life sciences --- actin waves --- curved proteins --- dynamic instability --- podosomes --- diffusion --- cell polarity --- Cdc42 --- stress --- cellular memory --- phase separation --- prions --- apoptotic extrusion --- oncogenic extrusion --- contractility --- actomyosin --- bottom-up synthetic biology --- motor proteins --- pattern formation --- self-organization --- cell motility --- signal transduction --- actin dynamics --- intracellular waves --- polarization --- direction sensing --- symmetry-breaking --- biphasic responses --- reaction-diffusion --- membrane and cortical tension --- cell fusion --- cortexillin --- cytokinesis --- Dictyostelium --- myosin --- symmetry breaking --- cytoplasmic flow --- phase-space analysis --- nonlinear waves --- actin polymerization --- bifurcation theory --- mass conservation --- spatial localization --- activator–inhibitor models --- developmental transitions --- cell polarization --- mathematical model --- fission yeast --- reaction–diffusion model --- small GTPases --- Cdc42 oscillations --- pseudopod --- Ras activation --- cytoskeleton --- chemotaxis --- neutrophils --- natural variation --- modelling --- activator-substrate mechanism --- mass-conserved models --- intracellular polarization --- partial differential equations --- sensitivity analysis --- GTPase activating protein (GAP) --- fission yeast Schizosaccharomyces pombe --- CRY2-CIBN --- optogenetics --- clustering --- positive feedback --- network evolution --- Saccharomyces cerevisiae --- polarity --- modularity --- neutrality --- actin waves --- curved proteins --- dynamic instability --- podosomes --- diffusion --- cell polarity --- Cdc42 --- stress --- cellular memory --- phase separation --- prions --- apoptotic extrusion --- oncogenic extrusion --- contractility --- actomyosin --- bottom-up synthetic biology --- motor proteins --- pattern formation --- self-organization --- cell motility --- signal transduction --- actin dynamics --- intracellular waves --- polarization --- direction sensing --- symmetry-breaking --- biphasic responses --- reaction-diffusion --- membrane and cortical tension --- cell fusion --- cortexillin --- cytokinesis --- Dictyostelium --- myosin --- symmetry breaking --- cytoplasmic flow --- phase-space analysis --- nonlinear waves --- actin polymerization --- bifurcation theory --- mass conservation --- spatial localization --- activator–inhibitor models --- developmental transitions --- cell polarization --- mathematical model --- fission yeast --- reaction–diffusion model --- small GTPases --- Cdc42 oscillations --- pseudopod --- Ras activation --- cytoskeleton --- chemotaxis --- neutrophils --- natural variation --- modelling --- activator-substrate mechanism --- mass-conserved models --- intracellular polarization --- partial differential equations --- sensitivity analysis --- GTPase activating protein (GAP) --- fission yeast Schizosaccharomyces pombe --- CRY2-CIBN --- optogenetics --- clustering --- positive feedback --- network evolution --- Saccharomyces cerevisiae --- polarity --- modularity --- neutrality