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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact

endocrine frailty --- osteoporosis --- hypogonadism --- diabetes --- thyroid disorders

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The number of older subjects is rapidly increasingly worldwide. As a consequence, the nature of clinical conditions is also changing. Traditional medicine and models of care have been based on the evaluation and treatment of single and usually acute conditions occurring in relatively young individuals. Today, the usual clinical manifestation of diseases is characterized by multiple and often chronic conditions affecting older people. In this scenario, frailty and dementia have been triggering special interest both in research and clinical settings due to their high prevalence, impact on the individual’s quality of life, and consequences for public health worldwide. These conditions aptly reflect the complexity of age-related pathological conditions, finding as causal factor a myriad of heterogeneous, interacting, and often still unclear pathophysiological processes. Indeed, their study is strongly affected by the difficulty to differentiate the effects of a normal aging process from eventual pathological deviations of the underlying systems. Their occurrence and trajectories over time are strongly affected by a wide array of factors and determinants that can be hardly attributed to the deficit/involvement of single biological systems and/or health domains. Moreover, environment and social factors also play a key role in the determination of phenotypes. The present Research Topic is aimed at widening our understanding of the frailty and dementia phenomena occurring with aging, in order to improve the clinical and public health approaches to these burdening conditions.

Dementia. --- Aging --- cognition --- caregiver --- Frailty --- dementia --- mild cognitive impairment --- aging --- cognitive frailty --- Alzheimer --- Psychological aspects. --- cognition --- caregiver --- Frailty --- dementia --- mild cognitive impairment --- aging --- cognitive frailty --- Alzheimer

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The number of older subjects is rapidly increasingly worldwide. As a consequence, the nature of clinical conditions is also changing. Traditional medicine and models of care have been based on the evaluation and treatment of single and usually acute conditions occurring in relatively young individuals. Today, the usual clinical manifestation of diseases is characterized by multiple and often chronic conditions affecting older people. In this scenario, frailty and dementia have been triggering special interest both in research and clinical settings due to their high prevalence, impact on the individual’s quality of life, and consequences for public health worldwide. These conditions aptly reflect the complexity of age-related pathological conditions, finding as causal factor a myriad of heterogeneous, interacting, and often still unclear pathophysiological processes. Indeed, their study is strongly affected by the difficulty to differentiate the effects of a normal aging process from eventual pathological deviations of the underlying systems. Their occurrence and trajectories over time are strongly affected by a wide array of factors and determinants that can be hardly attributed to the deficit/involvement of single biological systems and/or health domains. Moreover, environment and social factors also play a key role in the determination of phenotypes. The present Research Topic is aimed at widening our understanding of the frailty and dementia phenomena occurring with aging, in order to improve the clinical and public health approaches to these burdening conditions.

Dementia. --- Aging --- Psychological aspects. --- cognition --- caregiver --- Frailty --- dementia --- mild cognitive impairment --- aging --- cognitive frailty --- Alzheimer

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• EndNote
• RefWorks (Direct export to RefWorks)

This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact

Medicine --- Endocrinology --- endocrine frailty --- osteoporosis --- hypogonadism --- diabetes --- thyroid disorders

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People are progressively ageing all over the world, and it is estimated that the number of persons aged 60 or over will more than triple by 2100. This emerging population will experience an inevitable rise in dementia, mental health problems and chronic diseases. According to GBD (2010), neuropsychiatric disorders among older adults account for 6.6% of the total disability (DALYs) for this age group, with 15% suffering from a mental disorder. Multiple social, psychological and biological factors are determinant of mental health, as well as life stressors. Among these, the lack of independence, limited mobility, chronic diseases, pain, frailty or other mental and physical problems require long-term care. Beyond this, the elderly are more prone to experience events such as bereavement, a drop in socio-economic status, disability, which leads to isolation, loss of independence, loneliness and psychological distress. Mental health problems and needs assessment by health-care professionals and older people themselves are under-recognised, and the stigma surrounding mental illness makes people reluctant to seek help. The early investigation and diagnosis of these situations are crucial, as well as prior management with an important combination of pharmacological and psychosocial interventions, in conjunction with caregivers' and families' support. The present book aims to contribute to the development of knowledge in Aging and Mental Health, taking different approaches from authors, coming from diverse scientific fields, with the final goal being the improvement of quality of life and healthy aging for this growing population.

Aging --- Preventive mental health services for older people. --- Delirium --- Disability --- chronic diseases --- Aging --- Depression --- Frailty --- Mental Health --- Dementia --- Psychological aspects. --- Delirium --- Disability --- chronic diseases --- Aging --- Depression --- Frailty --- Mental Health --- Dementia