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apid progress in the understanding of carcinogenesis and pathology of epitheUal skin cancer has led to new strategies for the prevention Rand treatment of these malignancies. The goal of this volume is to comprehensively cover in a highly readable overview our present knowledge of pathogenetic mechanisms and molecular biology of Basal Cell and Squamous Cell Carcinomas. Topics that are discussed in-depth by leading researchers and clinicians range from the newest findings in epidemiology, histology, photobiology, immunology, cytogenetics, and molecular pathology to new concepts for prophylaxis and treatment. Experts in the field as well as health care professionals not intimately involved in these specialized areas are provided with the most significant and timely information related to these topics. It is the aim of this book to summarize essential up-to-date information for clinicians and scientists interested in the biology of Basal Cell and Squamous Cell Carcinomas. The chapters are written by authors who are experts in their respective research areas, and I am gratefixl for their willingness to contribute to this book. I would also like to express my thanks to Ron Landes, Cynthia Conomos, Sara Lord and all the other members of the Landes Bioscience staff for their expertise, diligence and patience in helping me complete this work. Jorg Reichrathy Prof, Dn med. CHAPTER 1 The Epidemiology of Basal Cell and Squamous Cell Carcinoma Hao Wang and Thomas L.
Skin --- Basal cell carcinoma --- Squamous cell carcinoma --- Cancer --- Genetic aspects. --- SCC (Oncology) --- Squamous cell cancer --- Basal cell cancer --- Basal cell epithelioma --- Epithelioma, Basal cell --- Foot cell carcinoma --- Rodent ulcer --- Oncology. --- Oncology . --- Pathology. --- Cancer Research. --- Tumors --- Disease (Pathology) --- Medical sciences --- Diseases --- Medicine --- Medicine, Preventive --- Cancer research. --- Cancer research
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Basal Cell Carcinoma: Advances in Treatment and Research, edited and written by leaders with expertise in cutaneous oncology, dermatopathology, dermatology, Mohs micrographic surgery, head and neck surgery, oculoplastic surgery and radiation oncology, provides a comprehensive overview of evidence-based treatment approaches for the most common cancer worldwide - basal cell carcinoma. The first part of this book details the epidemiology, risk factors, pathophysiology, and different histologic subtypes of basal cell carcinoma highlighted with high-resolution histopathology images. The second part of the book provides an in-depth review of different treatment modalities including topical therapy, local immunotherapy with interferon, cryotherapy, electrodesiccation and curettage, radiotherapy, and surgical approaches with Mohs micrographic surgery, head and neck surgery, and oculoplastic surgery. The final part of book highlights the utilization of innovative technology such as photodynamic therapy and laser for the treatment of basal cell carcinoma as well as emerging systemic therapeutic options including hedgehog pathway inhibitors and immunotherapy for the difficult-to-treat disease state, advanced basal cell carcinoma. Meant for a multi-disciplinary audience of dermatologists, Mohs Surgeons, oncologists, head and neck surgeons, oculoplastic surgeons, radiation oncologists, this book serves as an informative practical guide for physicians, mid-level providers and trainees.
Dermatology. --- Oncology. --- Basal cell carcinoma. --- Basal cell cancer --- Basal cell epithelioma --- Epithelioma, Basal cell --- Foot cell carcinoma --- Rodent ulcer --- Skin --- Tumors --- Medicine --- Cancer --- Diseases --- Oncology . --- Plastic surgery. --- Otolaryngologic surgery. --- Plastic Surgery. --- Head and Neck Surgery. --- Operative otolaryngology --- Otolaryngologic surgery --- Surgery, Operative --- Surgery, Orificial --- Aesthetic surgery --- Cosmetic surgery --- Plastic surgery --- Reconstructive surgery --- Surgery, Aesthetic --- Surgery, Cosmetic --- Surgery, Reconstructive --- Transplantation of organs, tissues, etc. --- Plastic surgeons
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