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Previously considered rare, Peyronie's disease affects nearly 10% of adult men. Recent advances in wound-healing disorders have substantially increased the understanding of Peyronie's disease and its pathophysiology. In Peyronie's Disease: A Guide to Clinical Management, international authorities review the current nonsurgical and surgical therapeutic options for dealing with this fibrotic disorder. A variety of state-of-the-art research techniques is discussed, including tissue analysis, cell culture of fibroblasts derived from Peyronie's plaques, and animal models that attempt to mimic the in vivo process of tunica albuginea fibrosis while also providing an opportunity for manipulation with novel therapeutic techniques. Although there is no cure for Peyronie's diseases, this text discusses treatments that may result in physical improvement or help to stabilize the scarring process. For those with a more advanced disease, surgical options to correct the deformity in an effort to make the patients functional again are reviewed. Also discussed are the many misconceptions about Peyronie's disease, so that a practicing physician will be able to diagnose, treat, or refer the patient more appropriately. As the first medical text on the subject, Peyronie's Disease: A Guide to Clinical Management provides an up-to-date summary of the etiology, natural history, and pathophysiology of this disease as well as presents a review of the available medical and surgical treatment options.

Penile induration. --- Penis --- Diseases. --- Cavernitis, Fibrous --- Fibrous cavernitis --- Induration, Penile --- Penis plastica --- Peyronie's disease --- Van Buren's disease --- Diseases --- Urology. --- Surgery. --- Surgery, Primitive --- Medicine --- Genitourinary organs

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This book aims to provide specialists and practitioners with a reliable source of information on all aspects of Peyronie’s disease, which is too often still considered a mysterious condition. The focus is in particular on those aspects of the disease that are most hotly debated, including etiology, risk factors, nosology, natural history, and medical therapy. Clear guidance is also provided on surgical techniques, with explanation of why and when to apply plication surgery, corporoplasty, and plaque surgery and the best approach to complicated cases. Throughout, strenuous efforts have been made to ensure clarity and simplicity of expression and ease of consultation. While clear international guidelines are lacking, this has allowed the authors to devote much space to personal ideas, conveying the fascinating and sometimes conflicting nature of this field of medicine and, hopefully, stimulating further research.

Medicine & Public Health. --- Andrology. --- Medicine. --- Médecine --- Penile induration. --- Penile induration --- Penis --- Treatment. --- Diseases. --- Cavernitis, Fibrous --- Fibrous cavernitis --- Induration, Penile --- Penis plastica --- Peyronie's disease --- Van Buren's disease --- Diseases --- Generative organs, Male --- Human reproduction --- Men --- Endocrine aspects --- Physiology