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The only effective and safe treatment of celiac disease (CD) is a lifelong, strict exclusion of gluten, the so-called gluten-free diet (GFD). As a consequence, strict adherence to the GFD is highly successful and useful to achieve optimal control of symptoms in celiac patients, although, sometimes, nutritional problems can persist despite a strict exclusion of gluten. However, following a strict GFD is not easy and an updated quality assessment of available products is needed for further improvement in gluten-free product development. Similar to CD, GFD is the common dietary approach in non-celiac gluten/wheat sensitivity (NCGWS). NCGWS is another common gluten-related disorder without the diagnostic features of CD. Increasing interest in the association and interaction between irritable bowel syndrome (IBS), functional dyspepsia, and gluten-related disorders can expand our knowledge and understanding of the management of these disorders. In this respect, GFD is considered a therapeutic option in IBS and functional digestive disorders. New insights into the GFD are an exciting scientific challenge for researchers.

Research & information: general --- Biology, life sciences --- Food & society --- irritable bowel syndrome --- celiac disease --- nonceliac gluten/wheat sensitivity --- gluten-free diet --- AIDAI score --- amylase trypsin inhibitor --- non-celiac wheat sensitivity --- CD14 lymphocytes --- interleukin-1beta --- tumor necrosis factor-α --- non coeliac wheat sensitivity --- gluten --- FODMAPs --- functional dyspepsia --- Celiac disease --- iron deficiency without anemia --- dietary iron --- iron supplementation --- women --- refractory celiac disease --- remission --- nickel allergy --- allergic contact mucositis --- irritable bowel syndrome (IBS) --- low-nickel diet --- gluten-free products --- gluten containing products --- food composition database --- dietary reference intake --- prison diets --- irritable bowel disease --- FODMAP --- low FODMAP diet --- gluten free diet --- non-celiac gluten wheat sensitivity --- n/a

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The only effective and safe treatment of celiac disease (CD) is a lifelong, strict exclusion of gluten, the so-called gluten-free diet (GFD). As a consequence, strict adherence to the GFD is highly successful and useful to achieve optimal control of symptoms in celiac patients, although, sometimes, nutritional problems can persist despite a strict exclusion of gluten. However, following a strict GFD is not easy and an updated quality assessment of available products is needed for further improvement in gluten-free product development. Similar to CD, GFD is the common dietary approach in non-celiac gluten/wheat sensitivity (NCGWS). NCGWS is another common gluten-related disorder without the diagnostic features of CD. Increasing interest in the association and interaction between irritable bowel syndrome (IBS), functional dyspepsia, and gluten-related disorders can expand our knowledge and understanding of the management of these disorders. In this respect, GFD is considered a therapeutic option in IBS and functional digestive disorders. New insights into the GFD are an exciting scientific challenge for researchers.

Research & information: general --- Biology, life sciences --- Food & society --- irritable bowel syndrome --- celiac disease --- nonceliac gluten/wheat sensitivity --- gluten-free diet --- AIDAI score --- amylase trypsin inhibitor --- non-celiac wheat sensitivity --- CD14 lymphocytes --- interleukin-1beta --- tumor necrosis factor-α --- non coeliac wheat sensitivity --- gluten --- FODMAPs --- functional dyspepsia --- Celiac disease --- iron deficiency without anemia --- dietary iron --- iron supplementation --- women --- refractory celiac disease --- remission --- nickel allergy --- allergic contact mucositis --- irritable bowel syndrome (IBS) --- low-nickel diet --- gluten-free products --- gluten containing products --- food composition database --- dietary reference intake --- prison diets --- irritable bowel disease --- FODMAP --- low FODMAP diet --- gluten free diet --- non-celiac gluten wheat sensitivity --- irritable bowel syndrome --- celiac disease --- nonceliac gluten/wheat sensitivity --- gluten-free diet --- AIDAI score --- amylase trypsin inhibitor --- non-celiac wheat sensitivity --- CD14 lymphocytes --- interleukin-1beta --- tumor necrosis factor-α --- non coeliac wheat sensitivity --- gluten --- FODMAPs --- functional dyspepsia --- Celiac disease --- iron deficiency without anemia --- dietary iron --- iron supplementation --- women --- refractory celiac disease --- remission --- nickel allergy --- allergic contact mucositis --- irritable bowel syndrome (IBS) --- low-nickel diet --- gluten-free products --- gluten containing products --- food composition database --- dietary reference intake --- prison diets --- irritable bowel disease --- FODMAP --- low FODMAP diet --- gluten free diet --- non-celiac gluten wheat sensitivity

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Nutrition Reviews is an international, peer-reviewed journal dedicated to the publication of authoritative literature reviews that analyze and synthesize existing and emerging knowledge in the field of nutrition science.

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