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Induire une immunité contre l’allergène majeur félin Fel d1 chez les chats est l’idée séduisante qui se cache derrière le vaccin HypoCat™, actuellement en cours de développement au sein de la société Hypopet (Université de Zurich), comme alternative aux traitements classiques de l’allergie aux chats. L’objectif de ce travail de recherche bibliographique est de porter un regard critique sur cette innovation vaccinale, ainsi que d’en déterminer la pertinence dans le contexte de la gestion de l’allergie chez l’Homme.

Allergène majeur félin Fel d1 --- Allergie aux chats --- Sciences du vivant > Médecine vétérinaire & santé animale

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Opera --- Féart, Rose --- Fei, Liu-Li --- Fel, Marie --- Félisaz --- Felix, Gladys --- Feltesse-Oscombre --- Fer, Victoria --- Féraldy, Germaine --- Féraud, Auguste-Léon --- Feres, Maria --- Fernandi, Eugenio --- Feron, Walter --- Ferran, Henri --- Ferrare, Marthe --- Ferrario, Carla --- Ferraro, Pier Miranda --- Ferraud de Saint-Pol, Auguste Léon (?) --- Ferrer, Marisa --- Ferrucci --- Feru, Marcel --- Ferval --- Fierens-Peeters, Caroline --- Filistad, Aldo --- Filliaux, Paulette --- Finel, Paul --- Fischer, Adolphe --- Fischer, Pierre --- Fischer-Schwarzboeck

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The structure, uniformity, stability, and functions of virus-like particles (VLPs) have encouraged scientists to utilize them as a unique tool in various applications in biomedical fields. Their interaction with the innate immune system is of major importance for the adaptive immune response they induce. The innate immune cells and molecules recognize and interact with VLPs on the basis of two major characteristics: size and surface geometry. VLP-based vaccines against hepatitis B, human papilloma, malaria, and hepatitis E have been developed and are available in many countries around the world. Given the inherent immunogenicity of VLPs, they render themselves ideal for the development of new vaccines against infectious diseases as well as noncommunicable diseases, such as chronic inflammation or cancer. This Special Issue is designed to provide an up-to-date view of the latest progress in the development of VLP-based prophylactic and therapeutic vaccines and technologies for their generation.

Humanities --- Social interaction --- virus-like particle --- influenza A(H1N1)pdm09 --- vaccination --- pregnant women --- antibody titers --- norovirus --- VLP --- vaccine --- genotype --- pre-existing immunity --- cross-reactivity --- blocking antibodies --- original antigenic sin (OAS) --- HPVs --- vaccines --- virus-like particles (VLPs) --- minor capsid protein (L2) --- HCMV --- cytomegalovirus --- nanoparticle --- immune response --- Sudan virus --- mice --- horse --- purified IgG --- long-lived plasma cells --- antibodies --- multivalency --- virus-like particles --- antigenic analysis --- epitope characterization --- hepatitis E vaccine --- serological evaluation --- virion-like epitopes --- well-characterized vaccines --- hepatitis B virus --- surface (envelope) antigen --- sub-viral particle --- capsid --- antigen display --- platform --- viral quantification --- NTA --- flow virometry --- SRFM --- cryo-TEM --- SEM --- plant virus --- virus-like --- vaccine platform --- epitope --- antigen --- cat allergy --- Fel d 1 --- HypoCat™ --- IL-13 --- interleukin-13 --- Tfh cells --- cancer --- immunotherapy --- H7N9 --- pandemic influenza A --- avian flu --- IAV --- VLP vaccine --- virus-like particle --- influenza A(H1N1)pdm09 --- vaccination --- pregnant women --- antibody titers --- norovirus --- VLP --- vaccine --- genotype --- pre-existing immunity --- cross-reactivity --- blocking antibodies --- original antigenic sin (OAS) --- HPVs --- vaccines --- virus-like particles (VLPs) --- minor capsid protein (L2) --- HCMV --- cytomegalovirus --- nanoparticle --- immune response --- Sudan virus --- mice --- horse --- purified IgG --- long-lived plasma cells --- antibodies --- multivalency --- virus-like particles --- antigenic analysis --- epitope characterization --- hepatitis E vaccine --- serological evaluation --- virion-like epitopes --- well-characterized vaccines --- hepatitis B virus --- surface (envelope) antigen --- sub-viral particle --- capsid --- antigen display --- platform --- viral quantification --- NTA --- flow virometry --- SRFM --- cryo-TEM --- SEM --- plant virus --- virus-like --- vaccine platform --- epitope --- antigen --- cat allergy --- Fel d 1 --- HypoCat™ --- IL-13 --- interleukin-13 --- Tfh cells --- cancer --- immunotherapy --- H7N9 --- pandemic influenza A --- avian flu --- IAV --- VLP vaccine

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Liver --- Biliary tract --- Pancreas --- Liver Diseases. --- Pancreatic Diseases. --- Biliary Tract Diseases. --- Diseases --- Diseases. --- Gastroenterology. --- Hepatology. --- Bilious diseases and biliousness --- Hepatology --- Biliary Tract Disease --- Disease, Biliary Tract --- Diseases, Biliary Tract --- Tract Disease, Biliary --- Tract Diseases, Biliary --- Disease, Pancreatic --- Diseases, Pancreatic --- Pancreatic Disease --- Liver Dysfunction --- Disease, Liver --- Diseases, Liver --- Dysfunction, Liver --- Dysfunctions, Liver --- Liver Disease --- Liver Dysfunctions --- Biliary tree --- Liver Diseases --- Pancreatic Diseases --- Biliary Tract Diseases --- Gastroenterology --- Digestive organs --- Endocrine glands --- Exocrine glands --- Bile --- Abdomen --- Pàncrees. --- Fetge. --- Bilis. --- Gastroenterologia. --- Malalties del pàncrees. --- Malalties del fetge. --- Hepatopaties --- Malalties hepàtiques --- Hepatologia --- Cirrosi hepàtica --- Hepatitis --- Hepatitis B --- Hepatitis vírica --- Hepatopaties alcohòliques --- Insuficiència hepàtica --- Síndrome de Budd-Chiari --- Fibrosi quística --- Hipoglucèmia --- Pancreatitis --- Medicina interna --- Aparell digestiu --- Gastroenterologia pediàtrica --- Proctologia --- Tracte gastrointestinal --- Malalties de l'aparell digestiu --- Fel --- Digestió --- Humors corporals --- Àcids biliars --- Pigments biliars --- Fetge --- Tracte biliar --- Cèl·lules hepàtiques --- Bilis --- Cirurgia hepàtica --- Illots de Langerhans

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The structure, uniformity, stability, and functions of virus-like particles (VLPs) have encouraged scientists to utilize them as a unique tool in various applications in biomedical fields. Their interaction with the innate immune system is of major importance for the adaptive immune response they induce. The innate immune cells and molecules recognize and interact with VLPs on the basis of two major characteristics: size and surface geometry. VLP-based vaccines against hepatitis B, human papilloma, malaria, and hepatitis E have been developed and are available in many countries around the world. Given the inherent immunogenicity of VLPs, they render themselves ideal for the development of new vaccines against infectious diseases as well as noncommunicable diseases, such as chronic inflammation or cancer. This Special Issue is designed to provide an up-to-date view of the latest progress in the development of VLP-based prophylactic and therapeutic vaccines and technologies for their generation.

virus-like particle --- influenza A(H1N1)pdm09 --- vaccination --- pregnant women --- antibody titers --- norovirus --- VLP --- vaccine --- genotype --- pre-existing immunity --- cross-reactivity --- blocking antibodies --- original antigenic sin (OAS) --- HPVs --- vaccines --- virus-like particles (VLPs) --- minor capsid protein (L2) --- HCMV --- cytomegalovirus --- nanoparticle --- immune response --- Sudan virus --- mice --- horse --- purified IgG --- long-lived plasma cells --- antibodies --- multivalency --- virus-like particles --- antigenic analysis --- epitope characterization --- hepatitis E vaccine --- serological evaluation --- virion-like epitopes --- well-characterized vaccines --- hepatitis B virus --- surface (envelope) antigen --- sub-viral particle --- capsid --- antigen display --- platform --- viral quantification --- NTA --- flow virometry --- SRFM --- cryo-TEM --- SEM --- plant virus --- virus-like --- vaccine platform --- epitope --- antigen --- cat allergy --- Fel d 1 --- HypoCat™ --- IL-13 --- interleukin-13 --- Tfh cells --- cancer --- immunotherapy --- H7N9 --- pandemic influenza A --- avian flu --- IAV --- VLP vaccine --- n/a