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Albumin is playing an increasing role as a versatile, biodegradable drug carrier in clinical theranostics. By applying different techniques, smart drug-delivery systems can be developed from albumin in order to improve drug delivery of different active pharmaceutical ingredients, even small-molecule drugs, peptides or enzymes. Principally, three drug delivery technologies can be distinguished for binding small-molecule or peptide drugs through the charged amino acids, carboxyl, and amino groups of albumin: physical or covalent binding of the drug to albumin through a ligand- or protein-binding group, the fusion of drug with albumin or the encapsulation of drugs into albumin nanoparticles. The accumulation of albumin in inflamed tissues and solid tumours forms the rationale for developing albumin-based drug delivery systems for targeted drug delivery. Besides tumour therapy, albumin-based drug delivery systems can be successfully applied as anti-inflammatory and anti-thrombotic coating for medical devices. The development and optimization of albumin nanoparticles may also be a rational and promising tool for conventional or alternative administration routes in order to improve therapy. This collection provides an overview of the significant scientific research works in this field, which may inspire researchers towards further development and utilization of these smart drug delivery systems.

Medicine. --- plasma half-life extension --- albumin conjugation --- in vivo glucose-lowering activity --- glucagon-like peptide-1 --- quality by design --- rapid equilibrium dialysis --- muco-adhesion --- brain PAMPA --- RPMI 2650 nasal epithelial cell --- human serum albumin --- dimerization --- doxorubicin --- enhanced permeability and retention effect --- antitumor --- Arthrobacter globiformis --- gout --- half-life extension --- inverse electron demand Diels-Alder reaction --- site-specific albumin conjugation --- thermostability --- urate oxidase --- albumin --- anti-thrombotic --- CD39 --- coating of medical devices --- stent coating --- therapeutic fusion protein --- conjugates --- vanadium --- cancer --- prodrug --- hydrogels --- EPR/ESR spectroscopy --- release behavior --- disulfide --- glioma --- conjugate --- albumin binding moieties --- peptides --- Evans blue --- 4-(p-iodophenyl)butyric acid --- integrin αvβ6 --- integrin αvβ6 binding peptide --- improved pharmacokinetics --- PET imaging

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The aim of this Special Issue is to publish high quality papers concerning poultry nutrition and the interrelations between nutrition, metabolism, microbiota and the health of poultry. Therefore, I invite submissions of recent findings, as original research or reviews, on poultry nutrition, including, but not limited to, the following areas: the effect of feeding on poultry meat end egg quality; nutrient requirements of poultry; the use of functional feed additives to improve gut health and immune status; microbiota; nutraceuticals; soybean meal replacers as alternative sources of protein for poultry; the effects of feeding poultry on environmental impacts; the use of feed/food by-products in poultry diet; and feed technology.

Research & information: general --- Biology, life sciences --- Technology, engineering, agriculture --- Aflatoxin B1 --- Lactobacillus --- anti-fungal --- Aspergillus flavus --- in vitro --- poultry --- chickens --- ascorbic acid --- curcumin --- boric acid --- necrotic enteritis --- Salmonella Enteritidis --- broiler --- growth --- intestinal villi --- Salmonella --- broilers --- IBDV --- soybean isoflavones --- immune function --- viral protein 5 mRNA expression --- ducks --- zinc oxide --- phytase --- growth performance --- zinc utilization --- residual feed consumption --- quail --- high environmental temperature --- intestinal morphology --- duodenum --- intestinal absorption --- broilers feeding --- propolis --- bee pollen --- DHA --- omega-3 --- fatty acids --- enrichment --- selenium sources-levels --- selenium retention --- antioxidant capacity --- frozen meat --- embryonic development --- heat shock proteins --- immunoglobulin --- intracytoplasmic vacuoles --- L-arginine --- amino acids --- dietary supplementation --- humoral immunity --- Moringa oleifera --- laying performance --- health status --- energy requirement --- meat quality --- slow-growing broilers --- nutrient deposition --- xylanase --- arabinofuranosidases --- nutrient utilization --- immunity --- strain --- in ovo injection --- royal jelly --- chicken --- hatchability --- blood --- chitooligosaccharide --- intestinal integrity --- digestive function --- heat stress --- indigenous yellow-feathered breed --- denatonium benzoate --- genistein --- ggTas2Rs --- bitter taste receptors --- licorice --- Glycyrrhiza glabra --- beneficial effects --- pharmaceutical --- health --- turkey --- footpad dermatitis --- charcoal --- crude protein reduced diet --- compensatory growth --- omega-6 --- fatty acid --- nutrition --- performance --- antioxidant --- egg and meat quality --- fertility --- cholesterol --- CuZn-SOD --- HMG-CoA --- HSP70 --- laying hens --- L-Thr --- n/a --- vitamin B12 --- pekin ducks --- weight gain --- feed intake --- feed conversion ratio --- hematological indicator --- antibiotic --- hydrolysable polyphenol --- monoglyceride --- pathogen --- poultry feeding --- antioxidant status --- bamboo leaf extract --- cholesterol metabolism --- apoptosis --- autophagy --- heart --- kidney --- Camelina oil --- Camelina cake --- polyunsaturated fatty acids --- broiler chicken --- threonine --- metabolism --- blood parameter --- polyethylene glycol --- red grape pomace waste --- broiler chickens --- alternative energy source --- soybean lecithin --- phospholipids --- vegetable acid oil --- digestibility balance --- free fatty acids --- triacylglycerols --- mannanoligosaccharide --- oxidative status --- Partridge Shank chickens --- nanoparticles --- chromium --- supplementation --- electrophysiology --- Ussing chamber --- antibiotics --- intestinal health --- probiotics --- methionine --- reduced crude protein --- slaughter characteristics --- medicinal mushrooms --- Allium --- feed additive --- organosulfur compounds --- polyphenols --- levels --- sources --- carcass --- betaine --- Evans blue dye --- physiological responses --- feed additives --- prebiotics --- phytogenics --- organic acids --- anticoccidials --- Clostridium perfringens --- production performance --- essential oils --- housing system --- ISA brown --- production --- egg production --- green tea powder --- huainan partridge chicken --- lipoprotein lipase --- plasma lipid --- cadmium --- clay --- blood biochemical parameters --- multienzymes --- administration method --- enzyme dose --- blood constituents --- blood chemistry --- emulsifiers --- TBARs --- nutrient requirements --- growth indices --- modeling --- Chinese yellow-feathered chickens --- probiotic --- phytobiotic --- alternative ingredients --- lipid peroxidation --- biological nano-curcumin --- diet --- pathogens --- phytobiotics --- green tea --- pomegranate --- drinking water --- antiradical activity --- cecal microbiota --- SNP --- IGF1 --- IGFBP2 --- TGFß3 --- Hubbard F15 --- Cobb E --- meat --- bilberry leaves --- walnut leaves --- digestive enzyme activities --- blood haematology --- serum biochemistry

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

The aim of this Special Issue is to publish high quality papers concerning poultry nutrition and the interrelations between nutrition, metabolism, microbiota and the health of poultry. Therefore, I invite submissions of recent findings, as original research or reviews, on poultry nutrition, including, but not limited to, the following areas: the effect of feeding on poultry meat end egg quality; nutrient requirements of poultry; the use of functional feed additives to improve gut health and immune status; microbiota; nutraceuticals; soybean meal replacers as alternative sources of protein for poultry; the effects of feeding poultry on environmental impacts; the use of feed/food by-products in poultry diet; and feed technology.

Research & information: general --- Biology, life sciences --- Technology, engineering, agriculture --- Aflatoxin B1 --- Lactobacillus --- anti-fungal --- Aspergillus flavus --- in vitro --- poultry --- chickens --- ascorbic acid --- curcumin --- boric acid --- necrotic enteritis --- Salmonella Enteritidis --- broiler --- growth --- intestinal villi --- Salmonella --- broilers --- IBDV --- soybean isoflavones --- immune function --- viral protein 5 mRNA expression --- ducks --- zinc oxide --- phytase --- growth performance --- zinc utilization --- residual feed consumption --- quail --- high environmental temperature --- intestinal morphology --- duodenum --- intestinal absorption --- broilers feeding --- propolis --- bee pollen --- DHA --- omega-3 --- fatty acids --- enrichment --- selenium sources-levels --- selenium retention --- antioxidant capacity --- frozen meat --- embryonic development --- heat shock proteins --- immunoglobulin --- intracytoplasmic vacuoles --- L-arginine --- amino acids --- dietary supplementation --- humoral immunity --- Moringa oleifera --- laying performance --- health status --- energy requirement --- meat quality --- slow-growing broilers --- nutrient deposition --- xylanase --- arabinofuranosidases --- nutrient utilization --- immunity --- strain --- in ovo injection --- royal jelly --- chicken --- hatchability --- blood --- chitooligosaccharide --- intestinal integrity --- digestive function --- heat stress --- indigenous yellow-feathered breed --- denatonium benzoate --- genistein --- ggTas2Rs --- bitter taste receptors --- licorice --- Glycyrrhiza glabra --- beneficial effects --- pharmaceutical --- health --- turkey --- footpad dermatitis --- charcoal --- crude protein reduced diet --- compensatory growth --- omega-6 --- fatty acid --- nutrition --- performance --- antioxidant --- egg and meat quality --- fertility --- cholesterol --- CuZn-SOD --- HMG-CoA --- HSP70 --- laying hens --- L-Thr --- vitamin B12 --- pekin ducks --- weight gain --- feed intake --- feed conversion ratio --- hematological indicator --- antibiotic --- hydrolysable polyphenol --- monoglyceride --- pathogen --- poultry feeding --- antioxidant status --- bamboo leaf extract --- cholesterol metabolism --- apoptosis --- autophagy --- heart --- kidney --- Camelina oil --- Camelina cake --- polyunsaturated fatty acids --- broiler chicken --- threonine --- metabolism --- blood parameter --- polyethylene glycol --- red grape pomace waste --- broiler chickens --- alternative energy source --- soybean lecithin --- phospholipids --- vegetable acid oil --- digestibility balance --- free fatty acids --- triacylglycerols --- mannanoligosaccharide --- oxidative status --- Partridge Shank chickens --- nanoparticles --- chromium --- supplementation --- electrophysiology --- Ussing chamber --- antibiotics --- intestinal health --- probiotics --- methionine --- reduced crude protein --- slaughter characteristics --- medicinal mushrooms --- Allium --- feed additive --- organosulfur compounds --- polyphenols --- levels --- sources --- carcass --- betaine --- Evans blue dye --- physiological responses --- feed additives --- prebiotics --- phytogenics --- organic acids --- anticoccidials --- Clostridium perfringens --- production performance --- essential oils --- housing system --- ISA brown --- production --- egg production --- green tea powder --- huainan partridge chicken --- lipoprotein lipase --- plasma lipid --- cadmium --- clay --- blood biochemical parameters --- multienzymes --- administration method --- enzyme dose --- blood constituents --- blood chemistry --- emulsifiers --- TBARs --- nutrient requirements --- growth indices --- modeling --- Chinese yellow-feathered chickens --- probiotic --- phytobiotic --- alternative ingredients --- lipid peroxidation --- biological nano-curcumin --- diet --- pathogens --- phytobiotics --- green tea --- pomegranate --- drinking water --- antiradical activity --- cecal microbiota --- SNP --- IGF1 --- IGFBP2 --- TGFß3 --- Hubbard F15 --- Cobb E --- meat --- bilberry leaves --- walnut leaves --- digestive enzyme activities --- blood haematology --- serum biochemistry