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Biocatalysis, that is, the use of biological catalysts (enzymes, cells, etc.) for the preparation of highly valuable compounds is undergoing a great development, being considered an extremely sustainable approach to undertaking environmental demands. In this scenario, this book illustrates the versatility of applied biocatalysis for the preparation of drugs and other bioactive compounds through the presentation of different research articles and reviews, in which several authors describe the most recent developments in this appealing scientific area. By reading the excellent contributions gathered in this book, it is possible to have an updated idea about new advances and possibilities for a new exciting future.

n/a --- biotransformations --- glycosidases --- bacteria --- OcUGT1 --- antioxidant activity --- glycodiverfication --- benzoxathiepins --- coprostanol --- 7-methylguanosine iodide --- sulfuretin --- chondroitin sulfates --- 7-methylguanine arabinoside iodide --- 7-methyl-2?-deoxyguanosine iodide --- microalgae --- chitosan oligosaccharides --- deacetylation degree --- cholesterol --- Tecadenoson --- esterase --- metabolic pathways --- chitinases --- alcohol --- transglycosylation reaction --- MALDI-TOF --- photooxidation --- aqueous solubility --- ?-transaminase --- cascade --- nutraceutical --- antimuscarinic agents --- extraction --- rutin oligomers --- Alcalase® --- HPSEC --- Cladribine --- purine nucleoside phosphorylase --- pleiotropic effects --- biotransamination --- amino acid --- stereoselective --- laccase activity --- biocatalysis --- Ribavirin --- lyases --- chitosanases --- anti-inflammatory --- glycosaminoglycan --- polysaccharides --- amine transaminases --- ester hydrolysis --- Spirulina --- asymmetric synthesis --- reductive amination --- glycosyltransferase --- statins --- stereoselective synthesis --- xanthine oxidase inhibition --- reduction reaction --- pig liver esterase (PLE)

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Carbamates. --- Esterases. --- Organophosphorus Compounds. --- Enzyme inhibitors. --- Organophosphorus compounds. --- Carbamic acid. --- Antienzymes --- Estérases --- Composés organophosphorés --- Carbamique, Acide --- Basic Sciences. Chemistry --- Biochemistry --- Proteins and Enzymes --- Proteins and Enzymes. --- Organopyrophosphorus Compounds --- Compounds, Organophosphorus --- Compounds, Organopyrophosphorus --- Phosphorus --- Phosphorus Compounds --- Aminoformic Acids --- Carbamic Acids --- Acids, Aminoformic --- Acids, Carbamic --- Estérases --- Composés organophosphorés --- Organophosphorus Compound --- Organopyrophosphorus Compound --- Compound, Organophosphorus --- Compound, Organopyrophosphorus --- Esterase --- Carbamate --- Carbamates --- Esterases --- Organophosphorus Compounds

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The recent global events of the SARS-CoV-2 pandemic in 2020 have alerted the world to the urgent need to develop fast, sensitive, simple, and inexpensive analytical tools that are capable of carrying out a large number of quantitative analyses, not only in centralized laboratories and core facilities but also on site and for point-of-care applications. In particular, in the case of immunological tests, the required sensitivity and specificity is often lacking when carrying out large-scale screening using decentralized methods, while a centralized laboratory with qualified personnel is required for providing quantitative and reliable responses. The advantages typical of electrochemical and optical biosensors (low cost and easy transduction) can nowadays be complemented in terms of improved sensitivity by combining electrochemistry (EC) with optical techniques such as electrochemiluminescence (ECL), EC/surface-enhanced Raman spectroscopy (SERS), and EC/surface plasmon resonance (SPR). This Special Issue addresses existing knowledge gaps and aids in exploring new approaches, solutions, and applications for opto-electrochemical biosensors in the quantitative detection of disease markers, such as cancer biomarkers proteins and allergens, and pathogenic agents such as viruses. Included are seven peer-reviewed papers that cover a range of subjects and applications related to the strategies developed for early diagnosis.

Research & information: general --- Biology, life sciences --- Biochemistry --- gold nanoparticles --- doxycycline --- tetracycline --- SPR biosensor --- signal amplification --- clinical diagnosis --- microRNA --- electrochemical biosensor --- catalysts --- RedOx indicator --- cancer biomarker --- electrochemical immune platform --- human ST2 --- plasma --- pancreatic cancer --- collagen type I --- 4,4'-thiobisbenzenethiol --- nanogold --- electrochemical impedance spectroscopy --- surface plasmon resonance --- half antibody --- medical diagnostic devices --- peptide --- antifouling --- protease --- biomarker --- bioreceptor --- SARS-CoV-2 detection --- nasopharyngeal swab --- saliva --- serum --- droplets --- amperometric biosensor --- neural esterase --- acetylcholinesterase --- inhibition --- organophosphate --- design --- optimization --- mathematical model --- flux control --- dimensionless --- gold nanoparticles --- doxycycline --- tetracycline --- SPR biosensor --- signal amplification --- clinical diagnosis --- microRNA --- electrochemical biosensor --- catalysts --- RedOx indicator --- cancer biomarker --- electrochemical immune platform --- human ST2 --- plasma --- pancreatic cancer --- collagen type I --- 4,4'-thiobisbenzenethiol --- nanogold --- electrochemical impedance spectroscopy --- surface plasmon resonance --- half antibody --- medical diagnostic devices --- peptide --- antifouling --- protease --- biomarker --- bioreceptor --- SARS-CoV-2 detection --- nasopharyngeal swab --- saliva --- serum --- droplets --- amperometric biosensor --- neural esterase --- acetylcholinesterase --- inhibition --- organophosphate --- design --- optimization --- mathematical model --- flux control --- dimensionless

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Molecular biology --- Biologie moléculaire --- Laboratoire --- laboratories --- Enzymes --- Bacteria --- Bacteriophages --- Plasmide --- plasmids --- Clonage --- cloning --- genomes --- genes --- Électrophorèse --- Electrophoresis --- Hybridation --- Hybridization --- Centrifugation --- Centrifuging --- Sécurité --- safety --- Méthylation --- Methylation --- ADN --- DNA --- Nucléase --- Nucleases --- Estérase --- Esterases --- GENETIC TECHNIQUES --- MICROBIOLOGICAL TECHNIQUES --- tables --- outlines --- tables. --- outlines. --- Genetic techniques --- Microbiological techniques --- Tables. --- Outlines. --- Biologie moléculaire --- Centrifuging. --- Methylation. --- DNA. --- Restriction --- Arn polymerase --- Topoisomerase --- BACTERIA --- VIRUS, BACTERIAL --- RADIOELEMENTS --- MOLECULAR CLONING --- GENES --- ENZYMES --- ELECTROPHORESIS --- CENTRIFUGATION --- SAFETY --- BIOLOGICAL STUDIES

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The recent global events of the SARS-CoV-2 pandemic in 2020 have alerted the world to the urgent need to develop fast, sensitive, simple, and inexpensive analytical tools that are capable of carrying out a large number of quantitative analyses, not only in centralized laboratories and core facilities but also on site and for point-of-care applications. In particular, in the case of immunological tests, the required sensitivity and specificity is often lacking when carrying out large-scale screening using decentralized methods, while a centralized laboratory with qualified personnel is required for providing quantitative and reliable responses. The advantages typical of electrochemical and optical biosensors (low cost and easy transduction) can nowadays be complemented in terms of improved sensitivity by combining electrochemistry (EC) with optical techniques such as electrochemiluminescence (ECL), EC/surface-enhanced Raman spectroscopy (SERS), and EC/surface plasmon resonance (SPR). This Special Issue addresses existing knowledge gaps and aids in exploring new approaches, solutions, and applications for opto-electrochemical biosensors in the quantitative detection of disease markers, such as cancer biomarkers proteins and allergens, and pathogenic agents such as viruses. Included are seven peer-reviewed papers that cover a range of subjects and applications related to the strategies developed for early diagnosis.

Research & information: general --- Biology, life sciences --- Biochemistry --- gold nanoparticles --- doxycycline --- tetracycline --- SPR biosensor --- signal amplification --- clinical diagnosis --- microRNA --- electrochemical biosensor --- catalysts --- RedOx indicator --- cancer biomarker --- electrochemical immune platform --- human ST2 --- plasma --- pancreatic cancer --- collagen type I --- 4,4′-thiobisbenzenethiol --- nanogold --- electrochemical impedance spectroscopy --- surface plasmon resonance --- half antibody --- medical diagnostic devices --- peptide --- antifouling --- protease --- biomarker --- bioreceptor --- SARS-CoV-2 detection --- nasopharyngeal swab --- saliva --- serum --- droplets --- amperometric biosensor --- neural esterase --- acetylcholinesterase --- inhibition --- organophosphate --- design --- optimization --- mathematical model --- flux control --- dimensionless --- n/a --- 4,4'-thiobisbenzenethiol