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Instability of flows and their transition to turbulence are widespread phenomena in engineering and the natural environment, and are important in applied mathematics, astrophysics, biology, geophysics, meteorology, oceanography and physics as well as engineering. This is a textbook to introduce these phenomena at a level suitable for a graduate course, by modelling them mathematically, and describing numerical simulations and laboratory experiments. The visualization of instabilities is emphasized, with many figures, and in references to more still and moving pictures. The relation of chaos to transition is discussed at length. Many worked examples and exercises for students illustrate the ideas of the text. Readers are assumed to be fluent in linear algebra, advanced calculus, elementary theory of ordinary differential equations, complex variables and the elements of fluid mechanics. The book is aimed at graduate students but will also be very useful for specialists in other fields.
Hydrodynamics. --- Stability. --- Hidrodinàmica --- Estabilitat
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Universities and colleges --- Administration. --- Professors universitaris --- Estabilitat laboral --- Administració universitària --- Gran Bretanya
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The course keeping and manoeuvring requirements for a ship are governed by international maritime law. In assessing and predicting the course keeping and manoeuvring capabilities of the ship, knowledge is required of the rudder forces necessary to keep a course or facilitate a manoeuvre. The second edition of Marine Rudders, Hydrofoils and Control Surfaces includes up-to-date data and rudder design techniques that enable the rudder forces to be estimated, together with any interactions due to the hull and propeller. The new edition describes the design and application of hydrofoils including shape adaptive design, and their applications including hydrofoil craft, yachts, and kite surfing hydrofoils. The professional will also face the need to design control surfaces for motion control, such as roll and pitch, for surface vessels and submersibles, and the book contains the necessary techniques and data to carry out these tasks.
Steering-gear. --- Ships --- Hydrodynamics. --- Hydrodynamics --- Naval architecture --- Stability of ships --- Rudder --- Marine engineering --- Dynamics --- Vaixells --- Servomotor del timó --- Hidrodinàmica. --- Arquitectura naval --- Hidrodinàmica --- Dinàmica --- Estabilitat --- Enginyeria naval
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Estabilitat --- Equacions diferencials --- Càlcul --- Funcions de Bessel --- Àlgebra diferencial --- Càlcul integral --- Càlcul operacional --- Equacions d'evolució --- Equacions de camp d'Einstein --- Equacions de Lagrange --- Equacions de Pfaff --- Equacions diferencials algebraiques --- Equacions diferencials ordinàries --- Equacions en derivades parcials --- Funcions de Green --- Funcions de Lyapunov --- Problemes de contorn --- Problemes inversos (Equacions diferencials) --- Teoria d'estabilitat (Matemàtica) --- Transformació de Laplace --- Dinàmica --- Equilibri --- Mecànica --- Lyapunov stability. --- Differential equations. --- 517.91 Differential equations --- Differential equations --- Liapunov stability --- Ljapunov stability --- Control theory --- Stability
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Dinàmica --- Sistemes borrosos --- Optimització matemàtica --- Mètodes de simulació --- Jocs d'estratègia (Matemàtica) --- Optimització combinatòria --- Programació dinàmica --- Programació (Matemàtica) --- Anàlisi de sistemes --- Lògica borrosa --- Cinètica --- Matemàtica --- Mecànica analítica --- Aerodinàmica --- Cinemàtica --- Caos (Teoria de sistemes) --- Dinàmica molecular --- Electrodinàmica --- Estabilitat --- Matèria --- Moviment --- Moviment rotatori --- Pertorbació (Matemàtica) --- Teoria quàntica --- Termodinàmica --- Estàtica --- Física --- Energia --- Mecànica --- Dynamics. --- Lògica difusa
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Equacions diferencials --- Càlcul --- Funcions de Bessel --- Àlgebra diferencial --- Càlcul integral --- Càlcul operacional --- Equacions d'evolució --- Equacions de camp d'Einstein --- Equacions de Lagrange --- Equacions de Pfaff --- Equacions diferencials algebraiques --- Equacions diferencials ordinàries --- Equacions en derivades parcials --- Funcions de Green --- Funcions de Lyapunov --- Problemes de contorn --- Problemes inversos (Equacions diferencials) --- Teoria d'estabilitat (Matemàtica) --- Transformació de Laplace --- Differential equations. --- 517.91 Differential equations --- Differential equations
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Equacions diferencials --- Solucions numèriques --- Anàlisi numèrica --- Càlcul --- Funcions de Bessel --- Àlgebra diferencial --- Càlcul integral --- Càlcul operacional --- Equacions d'evolució --- Equacions de camp d'Einstein --- Equacions de Lagrange --- Equacions de Pfaff --- Equacions diferencials algebraiques --- Equacions diferencials ordinàries --- Equacions en derivades parcials --- Funcions de Green --- Funcions de Lyapunov --- Problemes de contorn --- Problemes inversos (Equacions diferencials) --- Teoria d'estabilitat (Matemàtica) --- Transformació de Laplace
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Differential equations --- Equacions diferencials --- Càlcul --- Funcions de Bessel --- Àlgebra diferencial --- Càlcul integral --- Càlcul operacional --- Equacions d'evolució --- Equacions de camp d'Einstein --- Equacions de Lagrange --- Equacions de Pfaff --- Equacions diferencials algebraiques --- Equacions diferencials ordinàries --- Equacions en derivades parcials --- Funcions de Green --- Funcions de Lyapunov --- Problemes de contorn --- Problemes inversos (Equacions diferencials) --- Teoria d'estabilitat (Matemàtica) --- Transformació de Laplace --- 517.91 Differential equations
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Celebrating 100 years of HEP, this volume will discuss key pharmacological discoveries and concepts of the past 100 years. These discoveries have dramatically changed the medical treatment paradigms of many diseases and these concepts have and will continue to shape discovery of new medicinies. Newly evolving technologies will similarly be discussed as they will shape the future of the pharmacology and, accordingly, medical therapy.
Pharmacology, Experimental. --- Experimental pharmacology --- Therapeutics, Experimental --- Pharmacology. --- Pharmacology/Toxicology. --- Drug effects --- Medical pharmacology --- Medical sciences --- Chemicals --- Chemotherapy --- Drugs --- Pharmacy --- Physiological effect --- Pharmacology --- Farmacologia --- Medicina --- Biofarmàcia --- Biotransformació (Metabolisme) --- Dermofarmacologia --- Desenvolupament de medicaments --- Estabilitat dels medicaments --- Farmacocinètica --- Farmacogenètica --- Farmacologia cardiovascular --- Farmacologia clínica --- Farmacologia dental --- Farmacologia geriàtrica --- Farmacologia molecular --- Farmacologia obstètrica --- Farmacologia ocular --- Farmacologia pediàtrica --- Farmacologia respiratòria --- Farmacologia renal --- Farmacologia veterinària --- Immunofarmacologia --- Isòtops radioactius en farmacologia --- Neurofarmacologia --- Psicofarmacologia --- Química farmacèutica --- Radiofàrmacs --- Resistència als medicaments --- Toxicologia --- Medicaments --- Quimioteràpia --- Fotofarmacologia --- Farmacologia.
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This volume covers several aspects of rational drug design, such as synthesis of novel bioactive drugs; development and application of new methodologies; computational methods valuable for the establishment of new approaches in drug discovery; and the effects of physical-chemical and ADMET properties of the designed potential drugs. Chapters guide readers through amyloid deposits, Saturation Transfer Difference (STD) NMR, methods on bioguided design, the importance of lipophilicity in drug design, ADMET, FRET, structural biology, and homology modeling. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Rational Drug Design: Methods and Protocols aims to ensure successful results in the further study of this vital field.
Toxicology. --- Pharmacology/Toxicology. --- Chemicals --- Medicine --- Pharmacology --- Poisoning --- Poisons --- Toxicology --- Disseny de medicaments --- Farmacologia --- Manuals de laboratori --- Tècniques de laboratori --- Medicina --- Biofarmàcia --- Biotransformació (Metabolisme) --- Dermofarmacologia --- Desenvolupament de medicaments --- Estabilitat dels medicaments --- Farmacocinètica --- Farmacogenètica --- Farmacologia cardiovascular --- Farmacologia clínica --- Farmacologia dental --- Farmacologia geriàtrica --- Farmacologia molecular --- Farmacologia obstètrica --- Farmacologia ocular --- Farmacologia pediàtrica --- Farmacologia respiratòria --- Farmacologia renal --- Farmacologia veterinària --- Immunofarmacologia --- Isòtops radioactius en farmacologia --- Neurofarmacologia --- Psicofarmacologia --- Química farmacèutica --- Radiofàrmacs --- Resistència als medicaments --- Toxicologia --- Medicaments --- Quimioteràpia --- Disseny de fàrmacs --- Disseny farmacèutic --- Fotofarmacologia
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