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Book
Neurochemical mechanisms of opiates and endorphins
Authors: ---
ISBN: 0890041660 Year: 1979 Publisher: New York, N.Y. Raven Press


Book
The opiate receptors
Author:
ISBN: 160761992X 9786612971334 1607619938 1282971336 Year: 2010 Publisher: Clifton, N.J. : Humana Press : Springer,

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Abstract

In 1988, Gavril W. Pasternak published the first edition of this seminal text. It was a lucid account of the latest knowledge on opiate receptors and related receptor subtypes, a then controversial field, providing an integrated approach correlating the biochemical, physiological, and pharmacological aspects of opiate reaction. Fully revised and expanded, The Opiate Receptors, 2nd edition presents all the advances made in the field in the past twenty years. It covers a wide variety of topics including, but not limited to, the following: pharmacology of opioid drugs; endogenous opioids; molecular biology of mu receptors; molecular biology of delta receptors; kappa opioid receptor gene and the regulatory mechanisms of its protein expression; opioid receptor signal transduction mechanisms; mu opioid receptor mediated analgesia and reward; kappa opioid receptor function; delta opioid receptor function; genetics of opioid receptor functions in mice; opioid receptor trafficking; opioid receptor dimerization; molecular modulation of in vivo tolerance; and genetics of opioid actions. Written by leading international researchers in the field, this new edition is as groundbreaking and vital as its predecessor.


Book
Opiate receptors and antagonists : from bench to clinic
Authors: --- ---
ISBN: 1588298817 9786612038105 1282038109 1597451975 Year: 2009 Publisher: New York, NY : Humana Press,

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Abstract

The evolution in our understanding of Opioid receptors and their subtypes is intimately linked to the development of new pharmacological treatments for diseases and disorders as diverse as addiction, self-injurious behavior, pain, cancer, inflammation, eating disorders, traumatic injury, pruritis and movement disorders. The contributions contained in Opioid Receptors and Antagonists: From Bench to Clinic represent efforts from leading international scientists and clinicians making use of the latest information emerging from the study of the opioid-receptor system. The authors use a variety of experimental and clinical approaches involving the fields of molecular biology, biochemistry, anatomy, pharmacology, behavioral neuroscience and psychiatry to illustrate rapidly developing experimental and therapeutic areas. Highlights include characterization of opioid receptors, chemistry and pharmacology of opiod antagonists for various receptor subtypes (Mu, Kappa, and Delta), discussion of therapeutic uses of opiod antagonists and exploration of innovative approaches to therapeutic drug delivery. Opioid Receptors and Antagonists: From Bench to Clinic offers a comprehensive view of recent work on opiod antagonist applications and uses in various clinical treatments. Emphasis is placed on disorders of the reward system. This volume serves as reference while also illuminating prospects for future research.

Keywords

Endorphins. --- Endorphins --- Opioids --- Nervous system --- Peptides --- Central Nervous System Agents --- Mental Disorders --- Investigative Techniques --- Chemistry, Pharmaceutical --- Receptors, Neuropeptide --- Neuropeptides --- Therapeutics --- Receptors, G-Protein-Coupled --- Diseases --- Physiological Effects of Drugs --- Sensory System Agents --- Pharmacologic Actions --- Chemistry --- Therapeutic Uses --- Amino Acids, Peptides, and Proteins --- Receptors, Neurotransmitter --- Psychiatry and Psychology --- Receptors, Cell Surface --- Pharmacology --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Receptors, Peptide --- Peripheral Nervous System Agents --- Nerve Tissue Proteins --- Chemicals and Drugs --- Natural Science Disciplines --- Proteins --- Chemical Actions and Uses --- Membrane Proteins --- Biological Science Disciplines --- Disciplines and Occupations --- Narcotic Antagonists --- Receptors, Opioid --- Substance-Related Disorders --- Drug Discovery --- Drug Therapy --- Opioid Peptides --- Drug Delivery Systems --- Health & Biological Sciences --- Human Anatomy & Physiology --- Pharmacy, Therapeutics, & Pharmacology --- Animal Biochemistry --- Receptors --- Antagonists --- Chemotherapy --- Antagonists. --- Receptors. --- Chemotherapy. --- Opioid receptors --- Endorphin receptors --- Morphine receptors --- Narcotic receptors --- Opiate receptors --- Medicine. --- Pharmacology. --- Biomedicine. --- Pharmacology/Toxicology. --- Organs (Anatomy) --- Neurosciences --- Opioid peptides

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