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This book focuses on ion mobility-mass spectrometry (IM-MS) and informatics approaches to improve traditional analysis of molecules by providing fundamentals and protocols for exploiting the potential of state-of-the-art IM-MS technology for the most common analytical applications. The chapters have been organized into four parts, each dealing with a particular set of IM-MS applications: 1) metabolomics and lipidomics; 2) proteomics and glycomics; 3) imaging and ambient ionization IM-MS; and 4) bioinformatic solutions for analyzing IM-MS data and deriving CCS values. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Ion Mobility-Mass Spectrometry: Methods and Protocols serves as an ideal resource for scientists delving into the technique's unprecedented analytical advantages, enabling novel qualitative and quantitative applications for the analysis of complex biological samples.

Espectroscòpia de mobilitat d'ions --- Manuals de laboratori --- Protocols clínics --- Plans d'actuació mèdica --- Protocols en medicina --- Protocols de diagnòstic clínic --- Protocols mèdics --- Protocols terapèutics --- Medicina clínica --- Històries clíniques --- Protocols d'infermeria --- Tècniques de laboratori --- Espectrometria de mobilitat d'ions --- Espectroscòpia --- Biochemistry. --- Mass spectroscopy. --- Mass Spectrometry. --- Mass spectra --- Mass spectrograph --- Mass spectroscopy --- Mass spectrum analysis --- Mass (Physics) --- Nuclear spectroscopy --- Spectrum analysis --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Biology --- Chemistry --- Medical sciences --- Composition --- Ions --- Espectrometria de masses --- Espectrògraf de masses --- Espectroscòpia nuclear --- Desorció-ionització amb làser assistit per matriu --- Espectrometria de masses amb ionització per electroesprai --- Espectrometria de masses de plasma acoblat inductivament --- Espectrometria de masses de temps de vol --- Propietats de la matèria --- Solucions (Química) --- Anions --- Bombardeig iònic --- Cations --- Descàrregues elèctriques a través de gasos --- Emissió termoiònica --- Ions metàl·lics --- Cristalls iònics --- Electròlisi --- Electrons --- Solucions iòniques