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Micro/nanofluidic chips have found increasing applications in the analysis of chemical and biological samples over the past two decades. Electrokinetics has become the method of choice in these micro/nano-chips for transporting, manipulating and sensing ions, (bio)molecules, fluids and (bio)particles, etc., due to the high maneuverability, scalability, sensitivity, and integrability. The involved phenomena, which cover electroosmosis, electrophoresis, dielectrophoresis, electrohydrodynamics, electrothermal flow, diffusioosmosis, diffusiophoresis, streaming potential, current, etc., arise from either the inherent or the induced surface charge on the solid-liquid interface under DC and/or AC electric fields. To review the state-of-the-art of micro/nanochip electrokinetics, we welcome, in this Special Issue of Micromachines, all original research or review articles on the fundamentals and applications of the variety of electrokinetic phenomena in both microfluidic and nanofluidic devices.
micro/nanofluidics --- streaming potential/current --- electrical sensing --- electrokinetics --- diffusioosmosis --- dielectrophoresis --- electroosmosis --- electrophoresis --- diffusiophoresis --- induced charge electrokinetics
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Micro/nanofluidics-based lab-on-a-chip devices have found extensive applications in the analysis of chemical and biological samples over the past two decades. Electrokinetics is the method of choice in these micro/nano-chips for transporting, manipulating, and sensing various analyte species (e.g., ions, molecules, fluids, and particles). This book aims to highlight the recent developments in the field of micro/nano-chip electrokinetics, ranging from the fundamentals of electrokinetics to the applications of electrokinetics to both chemo- and bio-sample handling.
History of engineering & technology --- electrokinetic micromixer --- induced-charge electroosmosis --- field-induced Debye screening --- AC field-effect flow control --- electrochemical ion relaxation --- Electroosmosis --- Power-law fluid --- Non-Newtonian fluid --- Asymmetric zeta potential --- organ-on-a-chip --- biosensors --- biomedical --- microfluidics --- in vivo models --- applications --- Microfilter --- Dielectrophoresis --- Particle separation, micropillar --- multi-layer structure --- electroosmotic flow (EOF) pump --- parallel fluid channels --- liquid metal electrodes --- microfluidic particle concentrator --- continuous and switchable particle flow-focusing --- composite electrode arrangement --- field-effect flow control --- multifrequency induced-charge electroosmosis --- simultaneous pumping and convective mixing --- dual-Fourier-mode AC forcing --- traveling-wave/standing-wave AC electroosmosis --- bacteriophage --- dielectrophoresis --- electric field --- electrophoresis --- electrokinetics --- virus --- time-periodic electroosmotic flow --- heterogeneous surface charge --- cylindrical microchannel --- stream function --- micro-mixing --- cross-membrane voltage --- ion concentration polarization --- desalination effect --- pump effect --- eddy current --- electroosmotic flow --- viscoelastic fluid --- nanofluidics --- ionic conductance --- electrical double layer --- droplet --- electrohydrodynamics --- phase field method --- non-uniform electric field --- Linear Phan-Thien–Tanner (LPTT) --- pH --- tunable focus --- liquid lens --- charge injection --- characterization --- carbon electrodes --- three-dimensional (3D) --- diagnostics --- Candidiasis --- n/a --- Linear Phan-Thien-Tanner (LPTT)
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Micro/nanofluidics-based lab-on-a-chip devices have found extensive applications in the analysis of chemical and biological samples over the past two decades. Electrokinetics is the method of choice in these micro/nano-chips for transporting, manipulating, and sensing various analyte species (e.g., ions, molecules, fluids, and particles). This book aims to highlight the recent developments in the field of micro/nano-chip electrokinetics, ranging from the fundamentals of electrokinetics to the applications of electrokinetics to both chemo- and bio-sample handling.
electrokinetic micromixer --- induced-charge electroosmosis --- field-induced Debye screening --- AC field-effect flow control --- electrochemical ion relaxation --- Electroosmosis --- Power-law fluid --- Non-Newtonian fluid --- Asymmetric zeta potential --- organ-on-a-chip --- biosensors --- biomedical --- microfluidics --- in vivo models --- applications --- Microfilter --- Dielectrophoresis --- Particle separation, micropillar --- multi-layer structure --- electroosmotic flow (EOF) pump --- parallel fluid channels --- liquid metal electrodes --- microfluidic particle concentrator --- continuous and switchable particle flow-focusing --- composite electrode arrangement --- field-effect flow control --- multifrequency induced-charge electroosmosis --- simultaneous pumping and convective mixing --- dual-Fourier-mode AC forcing --- traveling-wave/standing-wave AC electroosmosis --- bacteriophage --- dielectrophoresis --- electric field --- electrophoresis --- electrokinetics --- virus --- time-periodic electroosmotic flow --- heterogeneous surface charge --- cylindrical microchannel --- stream function --- micro-mixing --- cross-membrane voltage --- ion concentration polarization --- desalination effect --- pump effect --- eddy current --- electroosmotic flow --- viscoelastic fluid --- nanofluidics --- ionic conductance --- electrical double layer --- droplet --- electrohydrodynamics --- phase field method --- non-uniform electric field --- Linear Phan-Thien–Tanner (LPTT) --- pH --- tunable focus --- liquid lens --- charge injection --- characterization --- carbon electrodes --- three-dimensional (3D) --- diagnostics --- Candidiasis --- n/a --- Linear Phan-Thien-Tanner (LPTT)
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Micro/nanofluidics-based lab-on-a-chip devices have found extensive applications in the analysis of chemical and biological samples over the past two decades. Electrokinetics is the method of choice in these micro/nano-chips for transporting, manipulating, and sensing various analyte species (e.g., ions, molecules, fluids, and particles). This book aims to highlight the recent developments in the field of micro/nano-chip electrokinetics, ranging from the fundamentals of electrokinetics to the applications of electrokinetics to both chemo- and bio-sample handling.
History of engineering & technology --- electrokinetic micromixer --- induced-charge electroosmosis --- field-induced Debye screening --- AC field-effect flow control --- electrochemical ion relaxation --- Electroosmosis --- Power-law fluid --- Non-Newtonian fluid --- Asymmetric zeta potential --- organ-on-a-chip --- biosensors --- biomedical --- microfluidics --- in vivo models --- applications --- Microfilter --- Dielectrophoresis --- Particle separation, micropillar --- multi-layer structure --- electroosmotic flow (EOF) pump --- parallel fluid channels --- liquid metal electrodes --- microfluidic particle concentrator --- continuous and switchable particle flow-focusing --- composite electrode arrangement --- field-effect flow control --- multifrequency induced-charge electroosmosis --- simultaneous pumping and convective mixing --- dual-Fourier-mode AC forcing --- traveling-wave/standing-wave AC electroosmosis --- bacteriophage --- dielectrophoresis --- electric field --- electrophoresis --- electrokinetics --- virus --- time-periodic electroosmotic flow --- heterogeneous surface charge --- cylindrical microchannel --- stream function --- micro-mixing --- cross-membrane voltage --- ion concentration polarization --- desalination effect --- pump effect --- eddy current --- electroosmotic flow --- viscoelastic fluid --- nanofluidics --- ionic conductance --- electrical double layer --- droplet --- electrohydrodynamics --- phase field method --- non-uniform electric field --- Linear Phan-Thien-Tanner (LPTT) --- pH --- tunable focus --- liquid lens --- charge injection --- characterization --- carbon electrodes --- three-dimensional (3D) --- diagnostics --- Candidiasis
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Micromixers are an important component in micrototal analysis systems and lab-on-a-chip platforms which are widely used for sample preparation and analysis, drug delivery, and biological and chemical synthesis. The Special Issue "Analysis, Design and Fabrication of Micromixers II" published in Micromachines covers new mechanisms, numerical and/or experimental mixing analysis, design, and fabrication of various micromixers. This reprint includes an editorial, two review papers, and eleven research papers reporting on five active and six passive micromixers. Three of the active micromixers have electrokinetic driving force, but the other two are activated by mechanical mechanism and acoustic streaming. Three studies employs non-Newtonian working fluids, one of which deals with nano-non-Newtonian fluids. Most of the cases investigated micromixer design.
Research & information: general --- Biology, life sciences --- microfluidics --- micro-mixer --- micro-jet --- XFEL --- molecular imaging --- sample delivery --- steric effect --- power-law fluids --- boundary slip --- oscillatory electroosmotic flow --- mass transport rate --- passive mixing --- curved mixing structure --- confocal microscopy --- mixing efficiency --- light-actuated AC electroosmosis (LACE) --- microfluidic mixer --- optical virtual electrode --- electrokinetics --- computational fluid dynamics (CFD) --- 3D printing --- spiral micromixers --- dean flow --- trapezoidal cross-section --- mixing index --- convection and diffusion --- Kenics micromixer --- numerical simulation --- non-Newtonian fluids --- CMC solutions --- low Reynolds number --- passive micro-mixer --- mixing unit --- cross flow direction --- baffle impingement --- swirl motion --- mixing performance --- mixing --- micromixer --- density control --- lab on a chip --- pneumatically driven --- acoustic streaming --- acoustofluidics --- computational fluid dynamics --- artificial cilia --- flow manipulation --- biological/medical applications --- chaotic micromixer --- Nano-Non-Newtonian fluid --- mass mixing index --- thermal mixing index --- low generalized Reynolds number --- minimal mixing energy cost --- degree of mixing (DOM) --- modified Tesla micromixer --- tip clearance --- symmetric counter-rotating vortices --- drag and connection of interface --- n/a
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Microfluidics has seen a remarkable growth over recent decades, with its extensive applications in engineering, medicine, biology, chemistry, etc. Many of these real applications of microfluidics involve the handling of complex fluids, such as whole blood, protein solutions, and polymeric solutions, which exhibit non-Newtonian characteristics—specifically viscoelasticity. The elasticity of the non-Newtonian fluids induces intriguing phenomena, such as elastic instability and turbulence, even at extremely low Reynolds numbers. This is the consequence of the nonlinear nature of the rheological constitutive equations. The nonlinear characteristic of non-Newtonian fluids can dramatically change the flow dynamics, and is useful to enhance mixing at the microscale. Electrokinetics in the context of non-Newtonian fluids are also of significant importance, with their potential applications in micromixing enhancement and bio-particles manipulation and separation. In this Special Issue, we welcomed research papers, and review articles related to the applications, fundamentals, design, and the underlying mechanisms of non-Newtonian microfluidics, including discussions, analytical papers, and numerical and/or experimental analyses.
Technology: general issues --- History of engineering & technology --- microfluidics --- Janus droplet --- OpenFOAM --- volume of fluid method --- adaptive dynamic mesh refinement --- shear-thinning fluid --- electroosmosis --- elastic instability --- non-Newtonian fluid --- Oldroyd-B model --- electroosmotic flow --- micromixing performance --- heterogeneous surface potential --- wall obstacle --- power-law fluid --- bvp4c --- RK4 technique --- brownian motion --- porous rotating disk --- maxwell nanofluid --- thermally radiative fluid --- von karman transformation --- hybrid nanofluid --- entropy generation --- induced magnetic field --- convective boundary conditions --- thermal radiations --- stretching disk --- viscoelastic material --- group similarity analysis --- thermal relaxation time --- parametric investigation --- variable magnetic field --- error analysis --- viscoelastic fluid --- microfluid --- direction-dependent --- viscous dissipation --- chemical reaction --- finite element procedure --- hybrid nanoparticles --- heat and mass transfer rates --- joule heating --- tri-hybrid nanoparticles --- Soret and Dufour effect --- boundary layer analysis --- finite element scheme --- heat generation --- constructive and destructive chemical reaction --- particle separation --- viscoelastic flow --- inertial focusing --- spiral channel --- transient two-layer flow --- power-law nanofluid --- heat transfer --- Laplace transform --- nanoparticle volume fraction --- effective thermal conductivity --- fractal scaling --- Monte Carlo --- porous media --- power-law model --- bioheat equation --- human body --- droplet deformation --- viscoelasticity --- wettable surface --- dielectric field --- droplet migration --- wettability gradient --- n/a
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Microfluidics has seen a remarkable growth over recent decades, with its extensive applications in engineering, medicine, biology, chemistry, etc. Many of these real applications of microfluidics involve the handling of complex fluids, such as whole blood, protein solutions, and polymeric solutions, which exhibit non-Newtonian characteristics—specifically viscoelasticity. The elasticity of the non-Newtonian fluids induces intriguing phenomena, such as elastic instability and turbulence, even at extremely low Reynolds numbers. This is the consequence of the nonlinear nature of the rheological constitutive equations. The nonlinear characteristic of non-Newtonian fluids can dramatically change the flow dynamics, and is useful to enhance mixing at the microscale. Electrokinetics in the context of non-Newtonian fluids are also of significant importance, with their potential applications in micromixing enhancement and bio-particles manipulation and separation. In this Special Issue, we welcomed research papers, and review articles related to the applications, fundamentals, design, and the underlying mechanisms of non-Newtonian microfluidics, including discussions, analytical papers, and numerical and/or experimental analyses.
microfluidics --- Janus droplet --- OpenFOAM --- volume of fluid method --- adaptive dynamic mesh refinement --- shear-thinning fluid --- electroosmosis --- elastic instability --- non-Newtonian fluid --- Oldroyd-B model --- electroosmotic flow --- micromixing performance --- heterogeneous surface potential --- wall obstacle --- power-law fluid --- bvp4c --- RK4 technique --- brownian motion --- porous rotating disk --- maxwell nanofluid --- thermally radiative fluid --- von karman transformation --- hybrid nanofluid --- entropy generation --- induced magnetic field --- convective boundary conditions --- thermal radiations --- stretching disk --- viscoelastic material --- group similarity analysis --- thermal relaxation time --- parametric investigation --- variable magnetic field --- error analysis --- viscoelastic fluid --- microfluid --- direction-dependent --- viscous dissipation --- chemical reaction --- finite element procedure --- hybrid nanoparticles --- heat and mass transfer rates --- joule heating --- tri-hybrid nanoparticles --- Soret and Dufour effect --- boundary layer analysis --- finite element scheme --- heat generation --- constructive and destructive chemical reaction --- particle separation --- viscoelastic flow --- inertial focusing --- spiral channel --- transient two-layer flow --- power-law nanofluid --- heat transfer --- Laplace transform --- nanoparticle volume fraction --- effective thermal conductivity --- fractal scaling --- Monte Carlo --- porous media --- power-law model --- bioheat equation --- human body --- droplet deformation --- viscoelasticity --- wettable surface --- dielectric field --- droplet migration --- wettability gradient --- n/a
Choose an application
Microfluidics has seen a remarkable growth over recent decades, with its extensive applications in engineering, medicine, biology, chemistry, etc. Many of these real applications of microfluidics involve the handling of complex fluids, such as whole blood, protein solutions, and polymeric solutions, which exhibit non-Newtonian characteristics—specifically viscoelasticity. The elasticity of the non-Newtonian fluids induces intriguing phenomena, such as elastic instability and turbulence, even at extremely low Reynolds numbers. This is the consequence of the nonlinear nature of the rheological constitutive equations. The nonlinear characteristic of non-Newtonian fluids can dramatically change the flow dynamics, and is useful to enhance mixing at the microscale. Electrokinetics in the context of non-Newtonian fluids are also of significant importance, with their potential applications in micromixing enhancement and bio-particles manipulation and separation. In this Special Issue, we welcomed research papers, and review articles related to the applications, fundamentals, design, and the underlying mechanisms of non-Newtonian microfluidics, including discussions, analytical papers, and numerical and/or experimental analyses.
Technology: general issues --- History of engineering & technology --- microfluidics --- Janus droplet --- OpenFOAM --- volume of fluid method --- adaptive dynamic mesh refinement --- shear-thinning fluid --- electroosmosis --- elastic instability --- non-Newtonian fluid --- Oldroyd-B model --- electroosmotic flow --- micromixing performance --- heterogeneous surface potential --- wall obstacle --- power-law fluid --- bvp4c --- RK4 technique --- brownian motion --- porous rotating disk --- maxwell nanofluid --- thermally radiative fluid --- von karman transformation --- hybrid nanofluid --- entropy generation --- induced magnetic field --- convective boundary conditions --- thermal radiations --- stretching disk --- viscoelastic material --- group similarity analysis --- thermal relaxation time --- parametric investigation --- variable magnetic field --- error analysis --- viscoelastic fluid --- microfluid --- direction-dependent --- viscous dissipation --- chemical reaction --- finite element procedure --- hybrid nanoparticles --- heat and mass transfer rates --- joule heating --- tri-hybrid nanoparticles --- Soret and Dufour effect --- boundary layer analysis --- finite element scheme --- heat generation --- constructive and destructive chemical reaction --- particle separation --- viscoelastic flow --- inertial focusing --- spiral channel --- transient two-layer flow --- power-law nanofluid --- heat transfer --- Laplace transform --- nanoparticle volume fraction --- effective thermal conductivity --- fractal scaling --- Monte Carlo --- porous media --- power-law model --- bioheat equation --- human body --- droplet deformation --- viscoelasticity --- wettable surface --- dielectric field --- droplet migration --- wettability gradient
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