Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact

early life stress --- Major depression (MDD) --- emotion --- monoamine --- HPA

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

The early postnatal period is a crucial stage for hippocampal development. During this critical period, the neonatal hippocampus is highly sensitive to the detrimental consequences of adverse environmental factors. Extensive clinical and preclinical evidence has shown that traumatic events early in life have profound and persistent effects on hippocampal function and behavior. This research topic focuses on the acute and lasting effects of early-life stress on various developmental processes in the hippocampus, and aims to uncover the molecules that are responsible for early-life stress-programmed effects and underlie resilience or vulnerability to stress-related neuropsychiatric disorders later in life. We hope the articles in this research topic will provide novel insights and stimulate future studies on the mechanisms of early-life stress and brain development.

development --- molecular mechanism --- early-life stress --- plasticity --- Hippocampus --- psychiatric disorders

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Experiences during early life program the central nervous- and endocrine-systems with consequences for susceptibility to physical and mental disorders. These programming effects depend on genetic and epigenetic factors, and their outcome leads to an adaptive or maladaptive phenotype to a given later environmental context. This Research Topic focused on the hypothalamus-pituitary-adrenal (HPA)-axis and stress-related phenotypes, and on how HPA-axis programming by the environment precisely occurs. We included original research, mini-review and review papers on a broad range of topics related to HPA-axis programming.

Hypothalamic-pituitary-adrenal axis. --- HPA axis --- Vulnerability --- resilience --- early life stress --- materna

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact

Medicine --- Psychiatry --- early life stress --- Major depression (MDD) --- emotion --- monoamine --- HPA

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Adverse Childhood Experiences: Using Evidence to Advance Research, Practice, Policy, and Prevention defines ACEs, provides a summary of the past 20 years of ACEs research, as well as provides guidance for the future directions for the field. It includes a review of the original ACEs Study, definitions of ACEs, and how ACEs are typically assessed. Other content includes a review of how ACEs are related to mental and physical health outcome, the neurodevelopmental mechanisms linking ACEs to psychopathology, sexual violence and sexual health outcomes, and violence across the lifespan. Important and contemporary issues in the field, like reconsidering how ACEs should be defined and assessed, the appropriateness of routine ACEs screening, thinking about ACEs from a public health and global perspective, strategies for preventing ACEs, understanding ACEs and trauma-informed care and resilience, and the importance of safe stable and nurturing environments for children are discussed. Adverse Childhood Experiences is a useful evidence-based resource for professionals working with children and families, including physicians, nurses, social workers, psychologists, lawyers, judges, as well as public health leaders, policy makers, and government delegates. Reviews the past 20 years of ACEs research Examines ACEs and mental and physical health Discusses the neurodevelopment mechanisms of ACEs and psychopathology Examines ACEs and violence across the lifespan Reconsiders the definition and assessment of ACEs Examines the issue of routine ACEs screening Discusses ACEs from a public health and global perspective Summarizes effective ACEs prevention, trauma-informed care, and resilience Provides recommendations for the future directions of the ACEs field

Psychic trauma in children. --- Child psychology. --- Psychology, Child --- Child --- Infant --- Stress Disorders, Traumatic --- Adaptation, Psychological --- therapy --- Adaptation, Psychologic --- Coping Skills --- Psychological Adaptation --- Behavior, Adaptive --- Coping Behavior --- Adaptive Behavior --- Adaptive Behaviors --- Behavior, Coping --- Behaviors, Adaptive --- Behaviors, Coping --- Coping Behaviors --- Coping Skill --- Psychologic Adaptation --- Skill, Coping --- Skills, Coping --- Allostasis --- Resilience, Psychological --- Infants --- Children --- Minors --- Psychology, Infant --- Psychology, Pediatric --- Child Psychology --- Infant Psychology --- Pediatric Psychology --- Psychology, Developmental --- Behavior, Child --- Child behavior --- Child study --- Pediatric psychology --- Child development --- Developmental psychology --- Child psychopathology --- psychology --- Psychology --- Adjustment --- Trauma and Stressor Related Disorders --- Adverse Childhood Experiences. --- Early Life Stress --- Early-Life Stress --- Adverse Childhood Experience --- Childhood Experience, Adverse --- Childhood Experiences, Adverse --- Early Life Stresses --- Early-Life Stresses --- Life Stress, Early --- Life Stresses, Early --- Stress, Early Life --- Stress, Early-Life --- Stresses, Early Life --- Stresses, Early-Life --- Psychology, Child. --- Child. --- Infant. --- Adaptation, Psychological. --- therapy.