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EPIDEMIOLOGY, MOLECULAR --- SEQUENCE ANALYSIS, DNA --- DNA FINGER PRINTING --- DNA PROBES --- DNA PROBES, HLA --- ELECTROPHORESIS, POLYACRYLAMIDE GEL --- DIAGNOSTIC USE --- METHODS --- EPIDEMIOLOGY, MOLECULAR --- SEQUENCE ANALYSIS, DNA --- DNA FINGER PRINTING --- DNA PROBES --- DNA PROBES, HLA --- ELECTROPHORESIS, POLYACRYLAMIDE GEL --- DIAGNOSTIC USE --- METHODS
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Cancer --- Cancer --- Cancer --- Epidemiology, Molecular --- Genetic Counseling --- Genetic Screening --- Molecular epidemiology --- Neoplasms --- Neoplasms --- Epidemiology --- Genetic aspects --- Prevention --- genetics --- prevention & control
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Epidemiologie [Moleculaire ] --- Epidemiology--Molecular aspects --- Epidémiologie moléculaire --- Moleculaire epidemiologie --- Molecular epidemiology --- Kanker --- Cancer --- Carcinogenicity --- Carcinogenesis --- Epidemiology --- Oncogenesis --- Pathogenesis of cancer --- Tumorigenesis --- Molecular aspects --- Pathogenesis --- Pathology --- Genetic toxicology
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Molecular epidemiology --- Biometry --- Epidemiology, Molecular --- methods --- Epidemiology --- Biological statistics --- Biology --- Biometrics (Biology) --- Biostatistics --- Biomathematics --- Statistics --- Molecular aspects --- Statistical methods --- Biometry - methods
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Quatrième de collection : "Le premier cas de SIDA a été observé aux USA en 1981 et le virus VIH-1 isolé à l’Institut Pasteur de Paris en 1983. Il est rapidement apparu que le VIH-1 était pandémique et que l’épicentre était situé en Afrique centrale ; le passage d’un virus du chimpanzé à l’Homme au début du XXe siècle a constitué l’événement princeps de cette pandémie. Le VIH-1 présente une grande variabilité génomique et il a effectué une formidable diversification après son passage chez l’Homme, aboutissant ainsi à la définition de groupes, de sous-types et de formes recombinantes circulantes (CRFs pour « circulating recombinant forms »). La répartition de ces virus est différente d’un continent à l’autre. Pour résumer la situation, on peut dire qu’il existe plus de 50 VIH-1 différents et que ceci explique les très grandes difficultés de mise au point d’un vaccin. L’auteur de ce livre, François-Charles Javaugue, a eu le mérite, le courage et la ténacité de réaliser une cartographie mondiale des différents VIH-1 en retraçant l’histoire de leur mise en évidence, le tout à partir de plusieurs milliers de références bibliographiques issues de revues scientifiques spécialisées. Il s’agit d’un travail unique en langue Française qui, à un moment donné, c’est-à-dire fin 2010 début 2011 et début 2012, présente l’ensemble des données publiées et est une référence, sinon la référence, dans le domaine. Dans cet ouvrage très bien rédigé, le lecteur pénètrera dans le monde complexe mais passionnant d’une pandémie virale et de ses mécanismes."
HIV --- Acquired Immunodeficiency Syndrome --- Anti-HIV Agents --- Epidemiology, Molecular --- HIV (Viruses) --- AIDS (Disease) --- Molecular epidemiology --- Recombinant viruses --- Virus de l'immunodéficience humaine --- Sida --- Médicaments contre le sida --- Epidémiologie moléculaire --- Virus recombinants --- epidemiology --- Epidemiology --- Chemotherapy --- Epidémiologie --- Reassortant Viruses --- Molecular Epidemiology --- Molecular Epidemiology. --- Virus de l'immunodéficience humaine --- Médicaments contre le sida --- Epidémiologie moléculaire --- Epidémiologie --- HIV. --- Anti-HIV Agents. --- epidemiology. --- HIV - epidemiology --- Acquired Immunodeficiency Syndrome - epidemiology
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It provides a comprehensive review of public health genetics, including chapters on important general issues such as newborn and other genetic screening, the delivery of genetic services, and the ethical, legal and social implications of the use of genetics within public health. It also reviews relevant clinical topics, the historical background, cross-cultural aspects, and communication issues. Contributors come from a wide range of fields including epidemiology, biostatistics, health policy and management, health services research, behavioral and social sciences, ethics, law, health economics, and laboratory sciences. The first broad survey of the role of genetics in public health, with emphasis on the new molecular genetics. With the accelerating discovery of human genes, public health professionals are increasingly confronted with a large body of scientific information that will guide public health action. Because the broad mission of public health is to fulfill society's interest in assuring conditions in which people can be healthy, the integration of new genetic information in public health research, policy and program development is unavoidable. Public health leadership is urgently needed to use genetic information to improve health and prevent disease, and to address ethical, legal and social issues resulting from inappropriate use of such information. In the not too-distant future, disease prevention and health promotion programs will routinely consider whether or not to use genetic information to help target behavioral, medical or environmental intervention activities in order to maximize benefit and minimize costs and harm to individuals. In anticipation of the expected growth at the interface of genetics and public health, this book delineates a framework for the integration of advances in human genetics into public health practice.
Genetic screening --- Medical genetics --- Public health --- #GBIB:CBMER --- moleculaire genetica --- volksgezondheid --- menselijk genoom --- genetische counseling --- Community health --- Health services --- Hygiene, Public --- Hygiene, Social --- Public health services --- Public hygiene --- Sanitary affairs --- Social hygiene --- Health --- Human services --- Biosecurity --- Health literacy --- Medicine, Preventive --- National health services --- Sanitation --- Clinical genetics --- Diseases --- Heredity of disease --- Human genetics --- Medical sciences --- Pathology --- Genetic disorders --- Human chromosome abnormalities --- Medical screening --- génétique moléculaire --- santé publique --- génome humain --- conseil génétique --- Genetic aspects --- Diagnosis --- Genetic screening. --- Medical genetics. --- Public health. --- Public Health. --- Epidemiology, Molecular. --- Genetic Engineering. --- Genetic Predisposition to Disease --- Genetic Screening. --- Genetics, Biochemical. --- Health Planning. --- Preventive Medicine. --- prevention & control.
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The integration of molecular techniques into epidemiologic studies poses new challenges in design, conduct, and analysis. Ethical concerns that arise in molecular epidemiologic studies are considered also.
Communicable diseases --- Molecular epidemiology. --- Communicable Diseases --- Molecular Epidemiology. --- Molecular epidemiology --- Molecular Biology --- Epidemiologic Methods --- Genetic Techniques --- Public Health --- Infection --- Biology --- Investigative Techniques --- Biological Science Disciplines --- Medicine --- Bacterial Infections and Mycoses --- Biochemistry --- Environment and Public Health --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Diseases --- Natural Science Disciplines --- Health Occupations --- Chemistry --- Disciplines and Occupations --- Health Care --- Molecular Epidemiology --- Genetics --- Epidemiology --- Health & Biological Sciences --- Epidemiology. --- epidemiology. --- genetics. --- Genetic Epidemiology --- Epidemiology, Molecular --- Epidemiologies, Genetic --- Epidemiologies, Molecular --- Epidemiology, Genetic --- Genetic Epidemiologies --- Molecular Epidemiologies --- Molecular Typing --- Molecular aspects --- epidemiology --- genetics
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