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Aulton's pharmaceutics : the design and manufacture of medicines
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ISBN: 9780443101083 9780443101076 0443101086 0443101078 Year: 2007 Publisher: Edinburgh ; New York : Churchill Livingstone,

The chemistry and biology of antibiotics
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ISBN: 0444415645 0444873805 9780444873804 9780444996787 9780444415646 0444996788 Year: 1983 Publisher: Amsterdam Oxford New York Elsevier Scientific


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New leads and tagets in drug research : proceedings of the Alfred Benson symposium, Copenhagen, September 1-5, 1991
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ISBN: 8716108108 9788716108104 Year: 1992 Volume: vol 33 Publisher: Copenhagen Munksgaard


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Vaccinology : principles and practice
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ISBN: 9781405185745 1405185740 9781118345313 1118345347 1280698179 9786613675132 1118345320 1118345312 1118345339 Year: 2012 Publisher: Chichester, West Sussex : Wiley-Blackwell,

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"This book addresses a profound deficiency in the field of vaccine research and development, namely the lack of a single volume describing the design and construction of vaccine strategies from first principles to implementation. This is an authoritative textbook that details a comprehensive and systematic approach to the science of vaccinology focusing on not only basic science, but the many stages required to commercialize and navigate the regulatory requirements for human application both in the United States and Europe. The book has broad appeal to clinicians, scientific and medical researchers alike, and graduate students"--Provided by publisher.


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Pharmaceutical quality by design : principles and applications
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ISBN: 0128163720 0128157992 9780128163726 9780128157992 Year: 2019 Publisher: Waltham, MA : Elsevier,

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Pharmaceutical Quality by Design: Principles and Applications discusses the Quality by Design (QbD) concept implemented by regulatory agencies to ensure the development of a consistent and high-quality pharmaceutical product that safely provides the maximum therapeutic benefit to patients. The book walks readers through the QbD framework by covering the fundamental principles of QbD, the current regulatory requirements, and the applications of QbD at various stages of pharmaceutical product development, including drug substance and excipient development, analytical development, formulation development, dissolution testing, manufacturing, stability studies, bioequivalence testing, risk and assessment, and clinical trials. Contributions from global leaders in QbD provide specific insight in its application in a diversity of pharmaceutical products, including nanopharmaceuticals, biopharmaceuticals, and vaccines. The inclusion of illustrations, practical examples, and case studies makes this book a useful reference guide to pharmaceutical scientists and researchers who are engaged in the formulation of various delivery systems and the analysis of pharmaceutical product development and drug manufacturing process.

Chemoinformatics : Concepts, Methods, and Tools for Drug Discovery
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ISBN: 128036002X 9786610360024 1592598021 1588292614 9781588292612 Year: 2004 Publisher: Totowa, NJ : Humana Press : Imprint: Humana,

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In the post-genomic era, the role informatics technologies plays in chemical and pharmaceutical research has become increasingly important in data management and lead-compound identification. In Chemoinformatics: Concepts, Methods, and Tools for Drug Discovery, well-recognized pioneers and investigators from diverse professional environments survey the key concepts in the field, describe cutting-edge methods, and provide exemplary pharmaceutical applications. The authors explain the theory behind the crucial concepts of molecular similarity and diversity, describe the challenging efforts to use chemoinformatics approaches to virtual and high-throughput screening, and illuminate the latest developments in multidimensional QSAR analysis. Other topics of interest include the use of partitioning algorithms and classification methods for analyzing large compound databases, screening sets, and virtual screening for active molecules; different approaches to target class-specific library design; the generation of novel classes of molecular descriptors; and Web-based tools for chemical database access and management. Also presented are different methods for describing molecular chirality and conformational parameters and for predicting the drug-like character and basic ADME properties of compounds based on modeling their putative interactions with cytochrome P450 isoforms. State-of-the-art and user-friendly, Chemoinformatics: Concepts, Methods, and Tools for Drug Discovery illuminates the conceptual and methodological diversity of this rapidly evolving field and offers instructive examples of cutting-edge applications in the drug discovery process.

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