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Drug carriers (Pharmacy) --- Biomedical materials. --- Drug Carriers --- Drug Carrier --- Drug Delivery Systems --- Biocompatible materials --- Biomaterials --- Medical materials --- Medicine --- Biomedical engineering --- Materials --- Biocompatibility --- Prosthesis --- Carriers, Drug (Pharmacy) --- Drug carrier systems (Pharmacy) --- Drug vehicles (Pharmacy) --- Drugs --- Vehicles, Drug (Pharmacy) --- Drug delivery systems --- Carriers --- Vehicles --- Magnetic Iron Oxide Nanoparticles --- Bioartificial materials --- Hemocompatible materials --- Biomaterials (Biomedical materials)
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Drug carriers (Pharmacy) --- Peptides --- Drug Carriers --- Peptide --- Polypeptide --- Polypeptides --- Drug Carrier --- Magnetic Iron Oxide Nanoparticles --- Drug Delivery Systems --- Organic compounds --- Amino acids --- Carriers, Drug (Pharmacy) --- Drug carrier systems (Pharmacy) --- Drug vehicles (Pharmacy) --- Drugs --- Vehicles, Drug (Pharmacy) --- Drug delivery systems --- Physiological transport --- Carriers --- Vehicles
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Drug carriers (Pharmacy) --- Nanoparticles. --- Nano-particles --- NPs (Nanoparticles) --- Nanoscale particles --- Nanostructured materials --- Particles --- Carriers, Drug (Pharmacy) --- Drug carrier systems (Pharmacy) --- Drug vehicles (Pharmacy) --- Drugs --- Vehicles, Drug (Pharmacy) --- Drug delivery systems --- Carriers --- Vehicles
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Various pharmaceutical nanocarriers, such as nanospheres, nanocapsules, liposomes, micelles, cell ghosts, lipoproteins and some others are widely used for experimental (and already clinical) delivery of therapeutic and diagnostic agents. The use of nanoparticulate pharmaceutical carriers to enhance the in vivo efficiency of many drugs well established itself over the past decade both in pharmaceutical research and clinical setting. Looking into the future of the field of drug delivery, we have to think about the development of the next generation of pharmaceutical nanocarriers combining the whole variety of properties and allowing for the simultaneous performance of multiple functions. Surface modification of pharmaceutical carriers is often used to control their properties in a desirable fashion and make them to simultaneously perform several different functions. This book is all about these "futuristic" multifunctional medicines. Key features: -all chapters written by international leaders in the field -offers the most recent innovations and discoveries related to nanopharmaceuticals -detailed illustrations -latest volume in the Fundamental Biomedical Technologies series About the Editor: Vladimir P. Torchilin, Ph.D., D.Sc. is a Distinguished Professor and Chair of the Department of Pharmaceutical Sciences and Director, Center for Pharmaceutical Biotechnology and Nanomedicine, Northeastern University, Boston, Mass.
Nanoparticles. --- Drug carriers (Pharmacy) --- Nanomedicine. --- Medicine --- Nanotechnology --- Carriers, Drug (Pharmacy) --- Drug carrier systems (Pharmacy) --- Drug vehicles (Pharmacy) --- Drugs --- Vehicles, Drug (Pharmacy) --- Drug delivery systems --- Nanostructured materials --- Particles --- Carriers --- Vehicles --- Nanotechnology. --- Microbiology. --- Pharmacy. --- Medical Microbiology. --- Chemistry --- Materia medica --- Pharmacology --- Microbial biology --- Biology --- Microorganisms --- Molecular technology --- Nanoscale technology --- High technology --- Medical microbiology.
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Biotransformation --- Prodrugs --- Drug Carriers --- Pharmaceutical Preparations --- Drug carriers (Pharmacy) --- metabolism --- Biopharmaceutics. --- #Lilly --- Drugs --- Antibody-directed enzyme prodrug therapy --- Carriers, Drug (Pharmacy) --- Drug carrier systems (Pharmacy) --- Drug vehicles (Pharmacy) --- Vehicles, Drug (Pharmacy) --- Drug delivery systems --- Chemistry, Pharmaceutical --- Carriers --- Vehicles --- Prodrugs. --- Drug carriers (Pharmacy). --- Biopharmaceutics --- Pharmaceutics --- Pharmaceutic
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Nonsteroidal anti-inflammatory agents. --- Drug carriers (Pharmacy) --- Non-steroid anti-inflammatory agents --- Non-steroidal anti-inflammatory agents --- NSAIDs (Pharmacology) --- Anti-inflammatory agents --- Carriers, Drug (Pharmacy) --- Drug carrier systems (Pharmacy) --- Drug vehicles (Pharmacy) --- Drugs --- Vehicles, Drug (Pharmacy) --- Drug delivery systems --- Carriers --- Vehicles
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This book provides with a comprehensive overview of the role of drug transporters in drug disposition and efficacy/toxicity, as well as drug-drug interactions and recent advances in the field. Transporters are known determinants of drug disposition and efficacy/toxicity. In general, they are divided into solute carrier (SLC) and ATP binding cassette (ABC) families, and are located along cell membranes, where they mediate drug uptake into cells and export out of cells. Drug transporters are essential in maintaining cell homeostasis, and their gene mutations may cause or contribute to severe human genetic disorders, such as cystic fibrosis, neurological disease, retinal degeneration, anemia, and cholesterol and bile transport defects. Conversely, some diseases may also alter transporter functions and expressions, in turn aggravating disease process. Further, since over-expression of some ABC transporters is a potential contributor to multidrug-resistance (MDR), the book presents a number of strategies to overcome MDR, including ABC transporter inhibitors and applying epigenetic methods to modulate transporter expressions and functions. This book is useful for graduate students and professionals who are looking to refresh or expand their knowledge of this exciting field.
Drug carriers (Pharmacy) --- Carriers, Drug (Pharmacy) --- Drug carrier systems (Pharmacy) --- Drug vehicles (Pharmacy) --- Drugs --- Vehicles, Drug (Pharmacy) --- Drug delivery systems --- Carriers --- Vehicles --- Pharmacology. --- Pharmacy. --- Medicinal chemistry. --- Pharmacology/Toxicology. --- Drug Safety and Pharmacovigilance. --- Medicinal Chemistry. --- Chemistry, Medical and pharmaceutical --- Chemistry, Pharmaceutical --- Drug chemistry --- Medical chemistry --- Medicinal chemistry --- Pharmacochemistry --- Chemistry --- Medicine --- Materia medica --- Pharmacology --- Drug effects --- Medical pharmacology --- Medical sciences --- Chemicals --- Chemotherapy --- Pharmacy --- Physiological effect
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"Polymeric Nanoparticles as Promising Tool for Anti-cancer Therapeutics provides an understanding of polymeric compounds and their use in cancer therapies. The book begins by giving an overview of the current status, future challenges and potential utilization of polymeric nanoparticles. It then covers specific polymeric nanoparticles through contributions from world-renowned experts and researchers. Chapters examine specific polymeric nanoparticles, their development as potential targeted delivery systems, and cancer characteristics that can be targeted for therapy development. The book synthesizes current research trends in the field, thus enhancing existing knowledge of nanomedicine, drug delivery and therapeutic intervention strategies in human cancers"--
Antineoplastic agents. --- Drug targeting. --- Cancer. --- Polymers --- Neoplasms --- Nanoparticles --- Drug Carriers. --- therapeutic use. --- drug therapy. --- Anticancer agents --- Antineoplastic drugs --- Antineoplastics --- Antitumor agents --- Antitumor drugs --- Cytotoxic drugs --- Inhibitors, Neoplasm --- Neoplasm inhibitors --- Drugs --- Cancer --- Chemotherapy --- Drug Carrier --- Magnetic Iron Oxide Nanoparticles --- Drug Delivery Systems --- Cancers --- Carcinoma --- Malignancy (Cancer) --- Malignant tumors --- Tumors --- Site-specific drug delivery --- Targeting of drugs --- Target organs (Anatomy) --- Targeting --- Dosage forms
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The development of liposomes as a drug delivery system has fluctuated since its introduction in the late 1960's by A.D. Bangham. While academic research of liposomes as a model membrane system has always flourished, as the exponential growth of papers can testify, the application of these findings to medically useful products has gone through several crises. Following the original optimism in the 70's and early 80's, a period of severe skepticism ensued at the end of the 80's and beginning of the 90's, culminating in a moderate but real optimism in the mid 90's, as a result of a successful lau
Liposomes --- Drug carriers (Pharmacy) --- Drug targeting. --- Drugs --- Site-specific drug delivery --- Targeting of drugs --- Target organs (Anatomy) --- Carriers, Drug (Pharmacy) --- Drug carrier systems (Pharmacy) --- Drug vehicles (Pharmacy) --- Vehicles, Drug (Pharmacy) --- Drug delivery systems --- Phospholipid vesicles --- Bilayer lipid membranes --- Cytoplasm --- Phospholipids --- Therapeutic use. --- Targeting --- Dosage forms --- Carriers --- Vehicles --- Drug carriers --- Drug targeting --- Therapeutic use
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Drug carriers (Pharmacy) --- Nanostructured materials --- Analysis. --- Nanomaterials --- Nanometer materials --- Nanophase materials --- Nanostructure controlled materials --- Nanostructure materials --- Ultra-fine microstructure materials --- Microstructure --- Nanotechnology --- Carriers, Drug (Pharmacy) --- Drug carrier systems (Pharmacy) --- Drug vehicles (Pharmacy) --- Drugs --- Vehicles, Drug (Pharmacy) --- Drug delivery systems --- Carriers --- Vehicles
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