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Since its discovery 50 years ago, brain dopamine has been implicated in the control of movement and cognition, and is concerned with diverse brain diseases such as Parkinson's disease, schizophrenia and drug addiction. This book is an illustrated biography of the dopamine molecule, from its synthesis in the brain to its signalling mechanisms and ultimately to its metabolic breakdown. Using colour illustrations of positron emission tomography (PET) scans, each chapter presents a specific stage in the biochemical pathway for dopamine. Writing for researchers and graduate students, Paul Cumming presents a compilation of all that has been learned about dopamine through molecular imaging, a technology which allows the measurement of formerly invisible processes in the living brain. He reviews current technical controversies in the interpretation of dopamine imaging, and presents key results illuminating brain dopamine in illness and health.

Dopamine. --- Molecular radiobiology. --- Single-photon emission computed tomography. --- Tomography, Emission-Computed. --- Tomography, Emission. --- Molecular radiation biology --- Molecular biology --- Radiobiology --- SPECT (Tomography) --- Tomography, Emission --- Computerized emission tomography --- Emission tomography --- PET (Tomography) --- PET-CT (Tomography) --- Positron emission tomography --- Positron emission transaxial tomography --- Radionuclide tomography --- Scintigraphy, Tomographic --- Tomography, Radionuclide --- Diagnosis --- Diagnostic imaging --- Positrons --- Radioisotope scanning --- Biogenic amines --- Bromocriptine --- Catecholamines --- Neurotransmitters --- Data processing --- Emission --- Dopamine --- Single-photon emission computed tomography --- Molecular radiobiology --- Tomography, Emission-Computed --- Computed Tomographic Scintigraphy --- Emission-Computed Tomography --- Radionuclide Computer-Assisted Tomography --- Radionuclide Computerized Tomography --- Radionuclide-Computed Tomography --- Radionuclide-Emission Computed Tomography --- Tomography, Computerized Emission --- CAT Scan, Radionuclide --- CT Scan, Radionuclide --- Computerized Emission Tomography --- Radionuclide Tomography, Computed --- Scintigraphy, Computed Tomographic --- Tomography, Radionuclide-Computed --- CAT Scans, Radionuclide --- CT Scans, Radionuclide --- Computed Radionuclide Tomography --- Computed Tomography, Radionuclide-Emission --- Computer-Assisted Tomographies, Radionuclide --- Computer-Assisted Tomography, Radionuclide --- Computerized Tomography, Radionuclide --- Emission Computed Tomography --- Emission Tomography, Computerized --- Radionuclide CAT Scan --- Radionuclide CAT Scans --- Radionuclide CT Scan --- Radionuclide CT Scans --- Radionuclide Computed Tomography --- Radionuclide Computer Assisted Tomography --- Radionuclide Computer-Assisted Tomographies --- Radionuclide Emission Computed Tomography --- Scan, Radionuclide CAT --- Scan, Radionuclide CT --- Scans, Radionuclide CAT --- Scans, Radionuclide CT --- Tomographic Scintigraphy, Computed --- Tomographies, Radionuclide Computer-Assisted --- Tomography, Computed Radionuclide --- Tomography, Emission Computed --- Tomography, Radionuclide Computed --- Tomography, Radionuclide Computer-Assisted --- Tomography, Radionuclide Computerized --- Tomography, Radionuclide-Emission Computed --- 3,4-Dihydroxyphenethylamine --- 4-(2-Aminoethyl)-1,2-benzenediol --- Dopamine Hydrochloride --- Intropin --- Hydroxytyramine --- 3,4 Dihydroxyphenethylamine --- Hydrochloride, Dopamine --- Dihydroxyphenylalanine --- Levodopa

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This book focuses on fundamental and applied research on polymer processing and its effect on the final surface as the optimization of polymer surface properties results in the unique applicability of these over other materials. The development and testing of the next generation of polymeric and composite materials is of particular interest. Special attention is given to polymer surface modification, external stimuli-responsive surfaces, coatings, adhesion, polymer and composites fatigue analysis, evaluation of the surface quality and microhardness, processing parameter optimization, characterization techniques, among others.

Research & information: general --- Biology, life sciences --- thermoplastic polyurethanes blends --- pressure sensitive adhesives --- viscoelastic properties --- adhesion properties --- tack --- creep --- cohesion properties --- nano-structure functional film --- magnetron sputtering --- cellulose insulation polymer --- space charge --- hydrophobicity --- zinc oxide --- polytetrafluoroethylene --- bromoisobutyryl esterification --- cornstarch --- synthesis process --- past stability --- adhesion --- film properties --- mullite --- whiskers --- nonaqueous precipitation method --- aluminum fluoride --- polar transformation --- screw --- aspect ratio --- carbon nanotube --- dispersion --- masterbatch --- nanocomposite --- polyamide --- polyamide 6 --- halloysite nanotube --- functionalizing agent --- in situ polymerization --- melt blending --- polymorphism --- hydrothermal ageing --- polymers --- octaglycidyl-POSS --- DGEBA --- dicyandiamide --- accelerators --- corrosion --- protective coatings --- infrared spectroscopy --- rheology --- poplar wood --- waterborne UV lacquer product --- wood modification --- contact angle --- spectroscopy --- super-hydrophobic coating --- elastic sensor --- carbon nanotubes --- wearable electronics --- monitoring of breathing --- strain sensor --- polymer composite --- CNTs --- construction composite --- friction resistance --- surface state --- low dielectric constant --- PI --- irradiation --- dielectric loss --- tin compounds --- valsartan --- poly(vinyl chloride) --- additives --- average molecular weight --- weight loss --- functional group index --- PET --- polymer --- plasma jet --- tilted application --- ROS distribution --- UV --- VUV --- epoxy --- Joule heating --- fast curing --- accelerated forming --- shape memory --- Acrylonitrile Butadiene Styrene --- sound absorption --- 3D printing technology --- frequency --- thickness --- air gap --- polyvinyl alcohol --- cationic polyacrylamide --- polyvinyl chloride --- azodicarbonamide --- micro-structure --- diffusion plate --- micro injection molding --- grinding --- ethylene-octene-copolymer --- carbon fibers --- polyaniline --- polypyrrole --- thermoelectric composites --- surface coating --- dopamine hydrochloride --- graphene oxide --- surgical suture --- friction --- Poly(vinylidene chloride-co-acrylonitrile) (P(VDC-co-AN )) --- thermo-dynamic surface characterization --- surface free energy --- inverse gas chromatography --- visual traits --- computer vision and image processing --- basalt fiber --- epoxy composite --- glass transition temperature --- DMA --- TMA --- creep recovery --- stress-relaxation --- heterogeneous nucleation --- cell morphology --- injection molding foaming --- composite materials --- visualization --- gloss transition defect --- surface defect --- surface gloss --- shrinkage --- mold surface replication --- surface analysis --- injection molding --- polymer surface modification --- hydrophobic properties --- optimization --- mathematical modeling --- poly(ethylene glycol) (PEG) --- conjugation --- N,N′-disuccinimidyl carbonate (DSC) --- immobilization --- surface modification --- ultra-high molecular weight polyethylene --- cellulose nanofiber --- bionanocomposite --- melt-blending --- ethanol mixing