Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Activity. --- Arousal theory. --- Disinhibition. --- Displacement behaviour.

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Under the name of Frontotemporal Dementias (FTD) numerous hereditary and sporadic disorders are listed. FTD may take away speech and language, social skills and ethical judgement, wishes and will, empathy and emotions; it may also impair motor functions. FTD may affect men and women in midlife or during old age leading to the demolition of the uniqueness of the human mind. In the last decade of the 20th century and in the first two decades of the 21st century, progress in the understanding of clinical, neuropathological, biochemical, and genetic aspects of FTD has accelerated. The novel awareness about FTD has directed young generations of researchers toward the study of this complex group of disorders. This Volume has been formulated with the participation of some of the leading scientists who have contributed to the development of knowledge in the clinical and basic science arenas. It captures the current central elements that are relevant to an up-to-date understanding of causes and pathogenesis of multiple forms of FTD. The volume is an opus that represents a distillation of the work of many scientists and addresses the current directions in the study of one of the most complex groups of diseases. In view of its structure, the book could also be used as a textbook, that offers both a broad and deep analysis of major areas in FTD. This book, planned by the International Society for Frontotemporal Dementias, is distinctive as it opens a window to a wide landscape about the biology of FTD. Thus, the book represents a moment of reflection on the present state of our knowledge of FTD and a collective vision toward scientific progress. The authors of each chapter share their knowledge and vision aimed at reducing the suffering which is caused by FTD.

Neurosciences. --- Neurology . --- Human genetics. --- Neurology. --- Human Genetics. --- Genetics --- Heredity, Human --- Human biology --- Physical anthropology --- Medicine --- Nervous system --- Neuropsychiatry --- Neural sciences --- Neurological sciences --- Neuroscience --- Medical sciences --- Diseases --- Frontotemporal dementia. --- Dementia, Frontotemporal --- Disinhibition-Dementia-Parkinsonism-Amyotrophy complex --- FLDEM (Frontotemporal lobe dementia) --- Frontotemporal lobe dementia --- FTD (Frontotemporal dementia) --- Hereditary dysphasic disinhibition dementia --- Wilhelmsen-Lynch disease --- Presenile dementia --- Medical genetics. --- Neuroscience. --- Medical Genetics. --- Clinical genetics --- Heredity of disease --- Human genetics --- Pathology --- Genetic disorders --- Genetic aspects

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Cage stereotypies--abnormal, repetitive, unvarying and apparently functionless behaviours--are common in many captive animals, sometimes resulting in self-injury or decreased reproductive success. However, a general mechanistic or neurophysiological understanding of cage stereotypies has proved elusive. In contrast, stereotypies in human mental disorder, or those induced by drugs or brain lesions, are well understood, and are thought to result from the disinhibition of behavioural selection by the basal ganglia. In this study, we found that the cage stereotypies of captive bank voles also correlate with signs of altered response selection by the basal ganglia. Stereotypic bar-mouthing in the caged voles correlated with inappropriate responding in extinction learning, impairments of response timing, evidence of a knowledge-action dissociation, increased rates of behavioural activation, and hyperactivity. Furthermore, all these signs intercorrelated, implicating a single underlying deficit consistent with striatal disinhibition of response selection. Bar-mouthing thus appears fundamentally similar to the stereotypies of autists, schizophrenics, and subjects treated with amphetamine or basal ganglial lesions. These results represent the first evidence for a neural substrate of cage stereotypy. They also suggest that stereotypic animals may experience novel forms of psychological distress, and that stereotypy might well represent a potential confound in many behavioural experiments.

Abnormal behaviour. --- Activation. --- Amphetamine. --- Animal welfare. --- Animal. --- Animals. --- Autism. --- Bank vole. --- Bank voles. --- Bar mouthing. --- Basal ganglia. --- Brain. --- Cage. --- Disinhibition. --- Disorder. --- Distress. --- Drug. --- Drugs. --- Executive functioning. --- Experience. --- Experiment. --- Experiments. --- Extinction. --- Human. --- Hyperactivity. --- Impairments. --- Laboratory. --- Learning. --- Lesion. --- Lesions. --- Reproductive success. --- Response. --- Rodent. --- Rodents. --- Schizophrenia. --- Selection. --- Self-injury. --- Sign. --- Stereotypic. --- Stereotypies. --- Stereotypy. --- Striatal dysfunction. --- Success. --- Vole. --- Voles.

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

In an important new contribution to the literature of chaos, two distinguished researchers in the field of physiology probe central theoretical questions about physiological rhythms. Topics discussed include: How are rhythms generated? How do they start and stop? What are the effects of perturbation of the rhythms? How are oscillations organized in space? Leon Glass and Michael Mackey address an audience of biological scientists, physicians, physical scientists, and mathematicians, but the work assumes no knowledge of advanced mathematics. Variation of rhythms outside normal limits, or appearance of new rhythms where none existed previously, are associated with disease. One of the most interesting features of the book is that it makes a start at explaining "dynamical diseases" that are not the result of infection by pathogens but that stem from abnormalities in the timing of essential functions. From Clocks to Chaos provides a firm foundation for understanding dynamic processes in physiology.

Biological rhythms --- Biological rhythms. --- Mathematics. --- AV block. --- Cantor function. --- GABA receptors. --- Hodgkin-Huxley equations. --- Liapunov number. --- Parkinsonian tremor. --- accessory pathways. --- alternans. --- bistability. --- blood vessel rhythms. --- cardiac rhythm. --- circle map. --- depolarization. --- differential equations. --- dynamical diseases. --- electrocardiogram. --- equilibrium points. --- fibrillation. --- fictive locomotion. --- graphical iteration. --- hyperventilation. --- insulin administration. --- lamprey locomotion. --- mechanical ventilation. --- mutual inhibition. --- neuromuscular junction. --- organizing centers. --- quadratic map. --- refractory period. --- sequential disinhibition. --- tachycardia. --- vagus nerve.

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Next year (2018), we will be celebrating the 15th anniversary of the International Journal of Environmental Research and Public Health—IJERPH (ISSN 1660-4601). Hence, we are currently organizing a Special Issue to commemorate this important milestone. Founded in 2004, IJERPH has experienced a tremendous growth in terms of the number and quality of scientific publications. With a 2016 impact factor of 2.101, IJERPH now ranks among the top international journals in the emerging field of environmental research and public health. As described on our website (https://www.mdpi.com/journal/ijerph), IJERPH is a peer-reviewed journal that focuses on the publication of scientific and technical information on the impacts of natural phenomena and anthropogenic factors on the quality of our environment, the interrelationships between environmental health and the quality of life, as well as the socio-cultural, political, economic, and legal considerations related to environmental stewardship and public health. Its primary areas of research interests include: Gene-environment interactions Environmental genomics and proteomics Environmental toxicology, mutagenesis and carcinogenesis Environmental epidemiology and disease control Health risk assessment and management Ecotoxicology, and ecological risk assessment and management Natural resources damage assessment Environmental chemistry and computational modeling Environmental policy and management Environmental engineering and biotechnology Emerging issues in environmental health and diseases Environmental education and public health To help celebrate the 15th anniversary, you are kindly invited to submit original articles, critical reviews, research notes, and short communications on any of the above-listed topics. Please also encourage any of our colleagues who may be interested to submit manuscripts. We expect that this issue will attract considerable attention, as we prepare to celebrate the excellent scientific contributions and socio-economic impacts of IJERPH over the past 15 years.

Research & information: general --- transportation noise --- MTNR1B gene --- rs10830963 --- diabetes --- glycosylated hemoglobin --- circadian sleep-wake cycle --- gene-environment interactions --- adults --- cohort study --- metal mobility --- soil flushing --- soil reclamation --- agricultural soil --- EDDS deficiency --- child sexual abuse --- adolescents --- girls --- boys --- gender differences --- legal proceedings --- child-friendly justice --- prevention --- cervical Arabin pessary --- cerclage --- second trimester of pregnancy --- sepiolite --- adsorption --- potentially toxic elements --- modification --- regeneration --- Xiangjiang River --- air pollution --- neighborhood deprivation index --- preterm birth --- spatial approach --- participatory research --- second hand smoking --- communication media --- vulnerable populations --- migrants --- health care research --- quality assurance --- hospital management --- health inequities --- environmental vulnerability --- multi-criteria spatial analysis --- risk management tool --- hazardous substance --- road accidents --- online hate --- hate speech --- bystander --- perpetrator --- online disinhibition --- online discrimination --- cyber aggression --- Bothrops lanceolatus --- envenomation --- snakebite --- bacteria --- infection --- antibiotic susceptibility --- ADL --- disability --- health --- home --- usability --- parenting desire --- lesbian --- gay --- minority stress --- mediation --- demographic factor --- EQ-5D --- health-related quality of life --- depression --- family planning --- Bayesian --- spatial --- RDHS --- Rwanda --- suicide --- premature mortality --- young men --- Greenland --- Denmark --- head injury --- incidence --- national health insurance --- population-based study --- mortality --- traumatic brain injury --- polycystic ovary syndrome --- self-efficacy --- optimism --- acceptance of illness --- September 11 terrorist attacks --- pilot aircraft-assisted suicide --- copycat effect --- obesity --- endoscopy --- Helicobacter pylori --- BMI --- Saudi patients --- urban lake --- comprehensive nutrition status Index --- heavy metals --- health risk --- fuzzy comprehensive method --- physical fitness --- Mediterranean diet --- body composition --- dementia --- health services --- resource utilization --- dementia care --- informal care --- formal care --- cognitive disorder --- physical activity in pregnancy --- PPAQ --- quality of life --- WHOQoL-Bref --- pregnant women --- food availability --- eating away from home --- household food spending --- trace elements --- concentration --- microwave digester --- Wuhan --- soil contamination --- ecological risk --- tuberculosis --- screening for tuberculosis --- public health --- immigrants --- health impact assessments --- premature death --- equity impact --- health impact --- reduction of air pollution --- environmental inequalities --- spatial analysis --- small area --- AirQ --- traffic congestion --- activity-travel patterns --- real-time traffic data --- the uncertain geographic context problem (UGCoP) --- the neighborhood effect averaging problem (NEAP) --- evaluation --- method --- policy --- strategy --- social --- trend --- winter tourism --- climate change --- snow abundance index --- meteorological suitability index --- copula function --- spatial suitability assessment --- oral surgery --- oral medicine --- leucoplakia --- hyperkeratosis --- laser --- electronic waste --- informal recycling --- PBDEs --- soil --- dust --- Nigeria --- aerobic capacity --- attrition --- change-of-direction speed --- deputy sheriff --- graduation --- high-intensity running --- police --- strength endurance --- tactical --- roadside exposure --- inflammation biomarker --- Nepal --- PM2.5 --- oily sludge --- incineration --- kinetic --- modeling --- differential/integral method --- engineering --- curriculum proposals --- arbuscular mycorrhizal fungi --- global change --- grassland ecosystem --- stoichiometry --- phosphorus limitation --- unsafe behavior --- targeted intervention --- coal miners --- safety management --- bioaerosols --- influenza virus --- ferret animal model --- aerosol chamber --- dengue fever --- Aedes albopictus --- living environment --- logistic regression analysis --- China --- human capital --- multilevel linear regression --- self-rated mental health --- social capital --- groundwater --- iron and manganese removal --- biofilter --- food contamination --- gastrointestinal diseases --- morbidity --- deep neural networks --- evolutionary learning --- health literacy --- adolescent health --- Mexico --- health disparities --- motivation --- videogaming --- psychopathology --- adverse childhood experiences (ACEs) --- Hungarian representative adult sample --- opinion poll --- ACE Score Calculator --- influenza vaccination --- pneumonia --- population-based case-control study --- adolescent --- risk factors --- psychosocial --- socio-environmental --- behavior --- United States --- Latinos --- physical education --- social and emotional learning --- sport education model --- subjective well-being --- trait emotional intelligence --- social anxiety --- transportation noise --- MTNR1B gene --- rs10830963 --- diabetes --- glycosylated hemoglobin --- circadian sleep-wake cycle --- gene-environment interactions --- adults --- cohort study --- metal mobility --- soil flushing --- soil reclamation --- agricultural soil --- EDDS deficiency --- child sexual abuse --- adolescents --- girls --- boys --- gender differences --- legal proceedings --- child-friendly justice --- prevention --- cervical Arabin pessary --- cerclage --- second trimester of pregnancy --- sepiolite --- adsorption --- potentially toxic elements --- modification --- regeneration --- Xiangjiang River --- air pollution --- neighborhood deprivation index --- preterm birth --- spatial approach --- participatory research --- second hand smoking --- communication media --- vulnerable populations --- migrants --- health care research --- quality assurance --- hospital management --- health inequities --- environmental vulnerability --- multi-criteria spatial analysis --- risk management tool --- hazardous substance --- road accidents --- online hate --- hate speech --- bystander --- perpetrator --- online disinhibition --- online discrimination --- cyber aggression --- Bothrops lanceolatus --- envenomation --- snakebite --- bacteria --- infection --- antibiotic susceptibility --- ADL --- disability --- health --- home --- usability --- parenting desire --- lesbian --- gay --- minority stress --- mediation --- demographic factor --- EQ-5D --- health-related quality of life --- depression --- family planning --- Bayesian --- spatial --- RDHS --- Rwanda --- suicide --- premature mortality --- young men --- Greenland --- Denmark --- head injury --- incidence --- national health insurance --- population-based study --- mortality --- traumatic brain injury --- polycystic ovary syndrome --- self-efficacy --- optimism --- acceptance of illness --- September 11 terrorist attacks --- pilot aircraft-assisted suicide --- copycat effect --- obesity --- endoscopy --- Helicobacter pylori --- BMI --- Saudi patients --- urban lake --- comprehensive nutrition status Index --- heavy metals --- health risk --- fuzzy comprehensive method --- physical fitness --- Mediterranean diet --- body composition --- dementia --- health services --- resource utilization --- dementia care --- informal care --- formal care --- cognitive disorder --- physical activity in pregnancy --- PPAQ --- quality of life --- WHOQoL-Bref --- pregnant women --- food availability --- eating away from home --- household food spending --- trace elements --- concentration --- microwave digester --- Wuhan --- soil contamination --- ecological risk --- tuberculosis --- screening for tuberculosis --- public health --- immigrants --- health impact assessments --- premature death --- equity impact --- health impact --- reduction of air pollution --- environmental inequalities --- spatial analysis --- small area --- AirQ --- traffic congestion --- activity-travel patterns --- real-time traffic data --- the uncertain geographic context problem (UGCoP) --- the neighborhood effect averaging problem (NEAP) --- evaluation --- method --- policy --- strategy --- social --- trend --- winter tourism --- climate change --- snow abundance index --- meteorological suitability index --- copula function --- spatial suitability assessment --- oral surgery --- oral medicine --- leucoplakia --- hyperkeratosis --- laser --- electronic waste --- informal recycling --- PBDEs --- soil --- dust --- Nigeria --- aerobic capacity --- attrition --- change-of-direction speed --- deputy sheriff --- graduation --- high-intensity running --- police --- strength endurance --- tactical --- roadside exposure --- inflammation biomarker --- Nepal --- PM2.5 --- oily sludge --- incineration --- kinetic --- modeling --- differential/integral method --- engineering --- curriculum proposals --- arbuscular mycorrhizal fungi --- global change --- grassland ecosystem --- stoichiometry --- phosphorus limitation --- unsafe behavior --- targeted intervention --- coal miners --- safety management --- bioaerosols --- influenza virus --- ferret animal model --- aerosol chamber --- dengue fever --- Aedes albopictus --- living environment --- logistic regression analysis --- China --- human capital --- multilevel linear regression --- self-rated mental health --- social capital --- groundwater --- iron and manganese removal --- biofilter --- food contamination --- gastrointestinal diseases --- morbidity --- deep neural networks --- evolutionary learning --- health literacy --- adolescent health --- Mexico --- health disparities --- motivation --- videogaming --- psychopathology --- adverse childhood experiences (ACEs) --- Hungarian representative adult sample --- opinion poll --- ACE Score Calculator --- influenza vaccination --- pneumonia --- population-based case-control study --- adolescent --- risk factors --- psychosocial --- socio-environmental --- behavior --- United States --- Latinos --- physical education --- social and emotional learning --- sport education model --- subjective well-being --- trait emotional intelligence --- social anxiety