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Internationally renowned experts have provided data on their own studies, and discuss the relative usefulness of their work in relation to diabetic nephropathy. The first section describes the novel role of intrarenal renin-angiotensin-aldosterone system (RAAS) and oxidative stress in the development of diabetic nephropathy and discusses the current and novel pharmacological interventions in the treatment of diabetic nephropathy. The second section discusses other important contributors outside of the RAAS in the pathogenesis of diabetic nephropathy including AGE/RAGE, epithelial-mesenchymal-transition (EMT) and immune cytokines. Features: Provides novel information on various pathophysiological determinants in the development of diabetic nephropathy Provides novel information on various pharmacological interventions of diabetic nephropathy

Diabetic nephropathies. --- Diabetic kidney disease --- Diabetic kidney failure --- Diabetic nephropathy --- Diabetic renal failure --- Diabetes --- Kidneys --- Complications --- Diseases --- Renal medicine & nephrology

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Dieses Buch zeigt alle Auswirkungen der Volkskrankheit Diabetes Mellitus auf den Urogenitaltrakt bei Mann und Frau auf, deutlich über die diabetische Nephropathie und die diabetogenen Sexualfunktionsstörungen des Mannes hinausgehend. Gerade mitigierte neurogene Blasenfunktionsstörungen können zu einem Problem werden und Ursache für rezidivierende Harnwegsinfektionen sein. Ein praxisorientierter Begleiter für alle Ärzte, die sich täglich mit dieser Erkrankung in ihrem ärztlichen Alltag auseinandersetzen. This book examines the full scope of the secondary effects of diabetes mellitus on the male and female urogenital tract, going well beyond diabetic nephropathy and diabetogenic male sexual dysfunction. It is a practical companion for all physicians who deal with diabetes mellitus in their daily practice.

Diabetic nephropathies. --- Diabetes --- Diabetic kidney disease --- Diabetic kidney failure --- Diabetic nephropathy --- Diabetic renal failure --- Kidneys --- Complications. --- Complications and sequelae --- Complications --- Diseases

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Diabetes and Kidney Disease reviews the most up-to-date research on diabetic nephropathy, the current understanding of its pathophysiology, renal structural alterations and clinical features, and summarizes recent evidence-based clinical treatment modalities for the prevention and management of diabetic kidney disease.  General clinical aspects are covered, as well as an overview to the novel approaches being designed by leading researchers in the field. A convenient compendium for physicians involved in the care of diabetic patients with varying degrees of kidney involvement, Diabetes and Kidney Disease is also a handy resource for medical residents and students interested in the current status and future approaches to reducing the burden of diabetes and diabetic kidney disease.

Diabetic nephropathies --- Diabetic neuropathies --- Treatment. --- Diagnosis. --- Diabetic neuropathy --- Diabetes --- Nerves, Peripheral --- Diabetic kidney disease --- Diabetic kidney failure --- Diabetic nephropathy --- Diabetic renal failure --- Kidneys --- Complications --- Diseases --- Nephrology. --- Diabetes. --- Internal medicine. --- Internal Medicine. --- Medicine, Internal --- Medicine --- Brittle diabetes --- Diabetes mellitus --- IDDM (Disease) --- Insulin-dependent diabetes --- Ketosis prone diabetes --- Type 1 diabetes --- Carbohydrate intolerance --- Endocrine glands --- Diabetic acidosis --- Glycosylated hemoglobin --- Internal medicine

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This book presents the latest information on the clinical-pathological features of diabetic kidney disease. The data included is based on a cohort study of biopsy-proven diabetic nephropathy patients and nephrosclerosis patients, who were observed over a long term, and on the long-term registry for diabetic nephropathy (diabetic kidney disease) in Japan. It provides a clinical-pathological axis in clinical settings, including differential pathological/clinical diagnoses of CKD in diabetic patients (e.g. the presence of “classic” diabetic nephropathy and/or nephrosclerosis and/or other primary kidney diseases). The abundant biopsy specimens with long-term medical records provide a detailed pathological and clinical description. The book also includes urine-sample data for developing and validating possible candidates for novel biomarkers for diabetic kidney disease. Many countries, including Japan, have ageing populations, in which nephrosclerosis contributes to the progression of kidney lesions in patients with diabetic kidney disease. As such, a comparison of a diabetic nephropathy cohort with nephrosclerosis is indispensable to offer better treatments. This comprehensive and informative book is an indispensible reference resource for all physicians and researchers in the field of nephrology and diabetes. .

Nephrology. --- Diabetes. --- Brittle diabetes --- Diabetes mellitus --- IDDM (Disease) --- Insulin-dependent diabetes --- Ketosis prone diabetes --- Type 1 diabetes --- Carbohydrate intolerance --- Endocrine glands --- Diabetic acidosis --- Glycosylated hemoglobin --- Internal medicine --- Kidneys --- Diseases --- Diabetic nephropathies. --- Diabetic kidney disease --- Diabetic kidney failure --- Diabetic nephropathy --- Diabetic renal failure --- Diabetes --- Complications

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As Editor-in-Chief of the journal Diabetology, I am pleased to announce the Special Issue “Diabetology: Feature Papers 2021” is now published in book format. Diabetology (ISSN 2673-4540) is an international, peer-reviewed scientific open access journal that provides an advanced forum for studies related to epidemiology, etiology, pathophysiology, pathogenesis, management, complications, and prevention of diabetes, including the molecular, biochemical, and physiological aspects of diabetes. In this Special Issue, “Feature Papers”, we aim to publish outstanding contributions in the main fields covered by the journal, which will make a great contribution to the community. This book covers the whole spectrum of diabetology from risk screening, risk markers, pathways of disease in type 1 diabetes and insulin treatment, and management of the disease and comorbidities.

carpal tunnel syndrome --- ultrasound --- power doppler signal --- diabetes --- FINDRISC --- prediabetes --- metabolic syndrome --- young-adults --- N-acetyl-β-d-glucosaminidase (NAG) --- diabetic nephropathy --- chronic kidney disease (CKD) --- meta-analysis --- systematic review --- focus groups --- self-management of type 2 diabetes --- patients’ experiences --- healthcare professionals --- middle-aged population --- type 1 diabetes --- autoimmune diseases --- pancreatic β-cells --- tolerance --- regulatory T cells --- immunotherapy --- insulin --- banting --- best --- MacLeod --- collip --- limited-resource countries (LRC) --- insulin pumps --- blood glucose monitoring --- continuous blood glucose sensors --- COVID-19 --- SARS-CoV-2 --- ACE2 --- TMPRSS2 --- mucormycosis --- COVID-associated mucormycosis (CAM) --- mucins --- Diabetic Keto Acidosis (DKA) --- Metabolic-Stress-Associated Interactome (MSAI) --- olfactory neurovascular niche --- serine proteases --- ferroptosis --- redox-iron stress --- n/a --- patients' experiences