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"An Introduction to Protein Informatics is designed for a professional audience composed of researchers and practitioners within bioinformatics, molecular modeling, algorithm design, optimization, and pattern recognition. This book is also suitable as a graduate-level text for students in computer science, mathematics, and biomedicine."--Jacket.

Protein Conformation. --- Amino Acid Sequence. --- Computational Biology --- Models, Theoretical. --- Sequence Alignment. --- Proteins --- Bioinformatics --- Bio-informatique --- Protéines --- methods. --- Structure --- Mathematical models --- Computer simulation --- Simulation par ordinateur --- Protein Conformation --- Amino Acid Sequence --- Models, Theoretical --- Sequence Alignment --- 57.087 --- 57.087 Methods and techniques for parameter estimation. Recording of biological data --- Methods and techniques for parameter estimation. Recording of biological data --- Determination, Sequence Homology --- Sequence Homology Determination --- Alignment, Sequence --- Alignments, Sequence --- Determinations, Sequence Homology --- Sequence Alignments --- Sequence Homology Determinations --- Molecular Sequence Data --- Sequence Homology, Nucleic Acid --- Experimental Model --- Experimental Models --- Mathematical Model --- Model, Experimental --- Models (Theoretical) --- Models, Experimental --- Models, Theoretic --- Theoretical Study --- Mathematical Models --- Model (Theoretical) --- Model, Mathematical --- Model, Theoretical --- Models, Mathematical --- Studies, Theoretical --- Study, Theoretical --- Theoretical Model --- Theoretical Models --- Theoretical Studies --- Computer Simulation --- Systems Theory --- Amino Acid Sequences --- Sequence, Amino Acid --- Sequences, Amino Acid --- Protein Structure, Primary --- Primary Protein Structure --- Primary Protein Structures --- Protein Structures, Primary --- Structure, Primary Protein --- Structures, Primary Protein --- Peptides --- Conformation, Protein --- Conformations, Protein --- Protein Conformations --- Protein Folding --- Bio-informatics --- Biological informatics --- Biology --- Information science --- Computational biology --- Systems biology --- Structure&delete& --- methods --- Data processing --- Proteids --- Biomolecules --- Polypeptides --- Proteomics

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Comparative Genomics, Volume 1, provides a collection of robust protocols for molecular biologists beginning to use comparative genomic analysis tools in a variety of areas. Volume I contains the first four of seven sections. In the first section, the reader is introduced to genomes via a number of visualization tools that allow one to browse through a particular genome of interest. The second and third sections deal with comparative analysis at the level of individual sequences, and present methods useful in sequence alignment, the discovery of conserved sequence motifs, and the analysis of codon usage. The fourth section deals with the identification and structural characterization of non-coding RNA genes — this class of genes is particularly difficult to predict, and discovery of these elements is almost completely reliant on comparative genomics. Given the tremendous increase in available biosequence data over the past ten years, Comparative Genomics, Volume 1, is timely, comprehensive, and novel. A companion Volume 2 is also available from Humana Press.

Genomics --- Nucleotide sequence --- Methods --- Sequence Analysis --- Genetic Techniques --- Genetics --- Investigative Techniques --- Computational Biology --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Biology --- Biological Science Disciplines --- Natural Science Disciplines --- Disciplines and Occupations --- Health & Biological Sciences --- Methodology --- Natural Sciences --- Physical Sciences --- Discipline, Natural Science --- Disciplines, Natural Science --- Natural Science --- Natural Science Discipline --- Physical Science --- Science, Natural --- Science, Physical --- Sciences, Natural --- Sciences, Physical --- Biologic Sciences --- Biological Science --- Science, Biological --- Sciences, Biological --- Biological Sciences --- Life Sciences --- Biologic Science --- Biological Science Discipline --- Discipline, Biological Science --- Disciplines, Biological Science --- Life Science --- Science Discipline, Biological --- Science Disciplines, Biological --- Science, Biologic --- Science, Life --- Sciences, Biologic --- Sciences, Life --- Bio-Informatics --- Biology, Computational --- Computational Molecular Biology --- Bioinformatics --- Molecular Biology, Computational --- Bio Informatics --- Bio-Informatic --- Bioinformatic --- Biologies, Computational Molecular --- Biology, Computational Molecular --- Computational Molecular Biologies --- Molecular Biologies, Computational --- Investigative Technics --- Investigative Technic --- Investigative Technique --- Technic, Investigative --- Technics, Investigative --- Technique, Investigative --- Techniques, Investigative --- Genetic Technic --- Genetic Technics --- Genetic Technique --- Technic, Genetic --- Technics, Genetic --- Technique, Genetic --- Techniques, Genetic --- Analysis, Sequence --- Determination, Sequence --- Determinations, Sequence --- Sequence Determinations --- Sequence Determination --- Analyses, Sequence --- Sequence Analyses --- Methodological Studies --- Methodological Study --- Procedures --- Studies, Methodological --- Study, Methodological --- Method --- Procedure --- Analysis, Nucleic acid sequence --- Analysis, Nucleotide sequence --- Base sequence (Nucleic acids) --- DNA sequence --- Nucleic acid sequence analysis --- Nucleotide sequence analysis --- RNA sequence --- Sequence, Nucleotide --- Genome research --- Genomes --- methods --- Research --- Life sciences. --- Human genetics. --- Biochemistry. --- Cell biology. --- Life Sciences. --- Biochemistry, general. --- Human Genetics. --- Cell Biology. --- Cell biology --- Cellular biology --- Cells --- Cytologists --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Chemistry --- Medical sciences --- Heredity, Human --- Human biology --- Physical anthropology --- Biosciences --- Science --- Composition --- Cytology. --- Genètica humana --- Antropologia física --- Biologia humana --- Genètica --- Herència humana --- Citogenètica humana --- Cromosomes humans --- Genètica de poblacions humanes --- Genètica mèdica --- Genètica molecular humana --- Psicologia genètica --- Genoma humà

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A DNA barcode in its simplest definition is one or more short gene sequences taken from a standardized portion of the genome that is used to identify species through reference to DNA sequence libraries or databases. In DNA Barcodes: Methods and Protocols expert researchers in the field detail many of the methods which are now commonly used with DNA barcodes. These methods include the latest information on techniques for generating, applying, and analyzing DNA barcodes across the Tree of Life including animals, fungi, protists, algae, and plants. Written in the highly successful  Methods in Molecular Biology™ series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results in the laboratory.   Thorough and intuitive, DNA Barcodes: Methods and Protocols aids scientists in continuing to study methods from wet-lab protocols, statistical, and ecological analyses along with guides to future, large-scale collections campaigns.

DNA Barcoding, Taxonomic --- Data Mining --- Genetic markers. --- DNA data banks. --- Marqueurs génétiques --- Banques de données génétiques (Génétique légale) --- methods --- Genetic markers --- DNA data banks --- Information Storage and Retrieval --- Publication Formats --- Sequence Analysis, DNA --- Molecular Typing --- Investigative Techniques --- Medical Informatics Applications --- Information Science --- Sequence Analysis --- Genetic Techniques --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Publication Characteristics --- Medical Informatics --- Laboratory Manuals --- Methods --- Biology --- Health & Biological Sciences --- Genetics --- Marqueurs génétiques --- Banques de données génétiques (Génétique légale) --- Methodological Studies --- Methodological Study --- Procedures --- Studies, Methodological --- Study, Methodological --- Method --- Procedure --- Text Mining --- Mining, Data --- Mining, Text --- DNA Barcode, Taxonomic --- Phylogenetic DNA Barcode --- Phylogenetic DNA Barcoding --- Taxonomic DNA Barcode --- Taxonomic DNA Barcodes --- Taxonomic DNA Barcoding --- Barcode, Phylogenetic DNA --- Barcode, Taxonomic DNA --- Barcodes, Phylogenetic DNA --- Barcodes, Taxonomic DNA --- Barcoding, Phylogenetic DNA --- Barcoding, Taxonomic DNA --- Barcodings, Phylogenetic DNA --- Barcodings, Taxonomic DNA --- DNA Barcode, Phylogenetic --- DNA Barcodes, Phylogenetic --- DNA Barcodes, Taxonomic --- DNA Barcoding, Phylogenetic --- DNA Barcodings, Phylogenetic --- DNA Barcodings, Taxonomic --- Phylogenetic DNA Barcodes --- Phylogenetic DNA Barcodings --- Taxonomic DNA Barcodings --- Computer Science, Medical --- Health Information Technology --- Informatics, Clinical --- Informatics, Medical --- Information Science, Medical --- Clinical Informatics --- Medical Computer Science --- Medical Information Science --- Health Information Technologies --- Information Technologies, Health --- Information Technology, Health --- Medical Computer Sciences --- Medical Information Sciences --- Science, Medical Computer --- Technologies, Health Information --- Technology, Health Information --- Genetic Technic --- Genetic Technics --- Genetic Technique --- Technic, Genetic --- Technics, Genetic --- Technique, Genetic --- Techniques, Genetic --- Analysis, Sequence --- Determination, Sequence --- Determinations, Sequence --- Sequence Determinations --- Sequence Determination --- Analyses, Sequence --- Sequence Analyses --- Information Sciences --- Science, Information --- Sciences, Information --- Application, Medical Informatics --- Applications, Medical Informatics --- Informatics Applications, Medical --- Informatics Application, Medical --- Medical Informatics Application --- Investigative Technics --- Investigative Technic --- Investigative Technique --- Technic, Investigative --- Technics, Investigative --- Technique, Investigative --- Techniques, Investigative --- Typing, Molecular --- Analysis, DNA Sequence --- DNA Sequence Determination --- DNA Sequence Determinations --- DNA Sequencing --- Determination, DNA Sequence --- Determinations, DNA Sequence --- Sequence Determinations, DNA --- DNA Sequence Analysis --- Sequence Determination, DNA --- Analyses, DNA Sequence --- DNA Sequence Analyses --- Sequence Analyses, DNA --- Sequencing, DNA --- Data Files --- Data Linkage --- Data Retrieval --- Data Sources --- Data Storage --- Data Storage and Retrieval --- Information Extraction --- Information Storage --- Machine-Readable Data Files --- Information Retrieval --- Data File --- Data File, Machine-Readable --- Data Files, Machine-Readable --- Data Source --- Extraction, Information --- Files, Machine-Readable Data --- Information Extractions --- Machine Readable Data Files --- Machine-Readable Data File --- Retrieval, Data --- Storage, Data --- DNA bank databases --- DNA banking databases --- DNA databanks --- DNA databases --- Chromosome markers --- DNA markers --- Medicine. --- Human genetics. --- Plant genetics. --- Animal genetics. --- Biomedicine. --- Human Genetics. --- Animal Genetics and Genomics. --- Plant Genetics & Genomics. --- Plants --- Heredity, Human --- Human biology --- Physical anthropology --- Clinical sciences --- Medical profession --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Plant Genetics and Genomics.

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This book constitutes the refereed proceedings of the Fourth International Symposium on Bioinformatics Research and Applications, ISBRA 2008, held in Atlanta, GA, USA in May 2008. The 35 revised full papers presented together with 6 workshop papers and 6 invited papers were carefully reviewed and selected from a total of 94 submissions. The papers cover a wide range of topics, including clustering and classification, gene expression analysis, gene networks, genome analysis, motif finding, pathways, protein structure prediction, protein domain interactions, phylogenetics, and software tools.

Bioinformatics --- Computational biology --- Bio-informatique --- Congresses. --- Congrès --- Congresses --- Methods --- Microarray Analysis --- Gene Expression --- Computational Biology --- Sequence Analysis --- Genetic Techniques --- Investigative Techniques --- Biology --- Publication Formats --- Microchip Analytical Procedures --- Genetic Processes --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Chemistry Techniques, Analytical --- Genetic Phenomena --- Biological Science Disciplines --- Publication Characteristics --- Natural Science Disciplines --- Phenomena and Processes --- Disciplines and Occupations --- Biology - General --- Health & Biological Sciences --- Bio-Informatics --- Biology, Computational --- Computational Molecular Biology --- Molecular Biology, Computational --- Bio Informatics --- Bio-Informatic --- Bioinformatic --- Biologies, Computational Molecular --- Biology, Computational Molecular --- Computational Molecular Biologies --- Molecular Biologies, Computational --- Expression, Gene --- Expressions, Gene --- Gene Expressions --- Microarray Analytical Devices --- Microarray Microchips --- Nanoarray Analytical Devices --- Analysis, Microarray --- Analytical Device, Microarray --- Analytical Device, Nanoarray --- Analytical Devices, Microarray --- Analytical Devices, Nanoarray --- Device, Microarray Analytical --- Device, Nanoarray Analytical --- Devices, Microarray Analytical --- Devices, Nanoarray Analytical --- Microarray Analytical Device --- Microarray Microchip --- Microchip, Microarray --- Microchips, Microarray --- Nanoarray Analytical Device --- Methodological Studies --- Methodological Study --- Procedures --- Studies, Methodological --- Study, Methodological --- Method --- Procedure --- Genetic Concepts --- Genetic Phenomenon --- Genetic Process --- Concept, Genetic --- Concepts, Genetic --- Genetic Concept --- Phenomena, Genetic --- Phenomenon, Genetic --- Process, Genetic --- Processes, Genetic --- Microchip Analysis --- Analyses, Microchip --- Analysis, Microchip --- Analytical Procedure, Microchip --- Analytical Procedures, Microchip --- Microchip Analytical Procedure --- Procedure, Microchip Analytical --- Procedures, Microchip Analytical --- Natural Sciences --- Physical Sciences --- Discipline, Natural Science --- Disciplines, Natural Science --- Natural Science --- Natural Science Discipline --- Physical Science --- Science, Natural --- Science, Physical --- Sciences, Natural --- Sciences, Physical --- Investigative Technics --- Investigative Technic --- Investigative Technique --- Technic, Investigative --- Technics, Investigative --- Technique, Investigative --- Techniques, Investigative --- Biologic Sciences --- Biological Science --- Science, Biological --- Sciences, Biological --- Biological Sciences --- Life Sciences --- Biologic Science --- Biological Science Discipline --- Discipline, Biological Science --- Disciplines, Biological Science --- Life Science --- Science Discipline, Biological --- Science Disciplines, Biological --- Science, Biologic --- Science, Life --- Sciences, Biologic --- Sciences, Life --- Analytical Chemistry Methods --- Analytical Chemistry Techniques --- Analytical Chemistry Method --- Analytical Chemistry Technique --- Chemistry Method, Analytical --- Chemistry Methods, Analytical --- Chemistry Technique, Analytical --- Method, Analytical Chemistry --- Methods, Analytical Chemistry --- Technique, Analytical Chemistry --- Techniques, Analytical Chemistry --- Genetic Technic --- Genetic Technics --- Genetic Technique --- Technic, Genetic --- Technics, Genetic --- Technique, Genetic --- Techniques, Genetic --- Genetics --- Analysis, Sequence --- Determination, Sequence --- Determinations, Sequence --- Sequence Determinations --- Sequence Determination --- Analyses, Sequence --- Sequence Analyses --- methods --- Life sciences. --- Computers. --- Data mining. --- Pattern recognition. --- Bioinformatics. --- Life Sciences. --- Life Sciences, general. --- Theory of Computation. --- Computational Biology/Bioinformatics. --- Computation by Abstract Devices. --- Pattern Recognition. --- Data Mining and Knowledge Discovery. --- Bio-informatics --- Biological informatics --- Information science --- Systems biology --- Design perception --- Pattern recognition --- Form perception --- Perception --- Figure-ground perception --- Algorithmic knowledge discovery --- Factual data analysis --- KDD (Information retrieval) --- Knowledge discovery in data --- Knowledge discovery in databases --- Mining, Data --- Database searching --- Automatic computers --- Automatic data processors --- Computer hardware --- Computing machines (Computers) --- Electronic brains --- Electronic calculating-machines --- Electronic computers --- Hardware, Computer --- Computer systems --- Cybernetics --- Machine theory --- Calculators --- Cyberspace --- Biosciences --- Science --- Data processing --- Information theory. --- Computer science. --- Optical pattern recognition. --- Optical data processing --- Pattern perception --- Perceptrons --- Visual discrimination --- Informatics --- Communication theory --- Communication --- Pattern perception.

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In the past several years, DNA microarray technology has attracted tremendous interest in both the scientific community and in industry. With its ability to simultaneously measure the activity and interactions of thousands of genes, this modern technology promises unprecedented new insights into mechanisms of living systems. Currently, the primary applications of microarrays include gene discovery, disease diagnosis and prognosis, drug discovery (pharmacogenomics), and toxicological research (toxicogenomics). Typical scientific tasks addressed by microarray experiments include the identification of coexpressed genes, discovery of sample or gene groups with similar expression patterns, identification of genes whose expression patterns are highly differentiating with respect to a set of discerned biological entities (e.g., tumor types), and the study of gene activity patterns under various stress conditions (e.g., chemical treatment). More recently, the discovery, modeling, and simulation of regulatory gene networks, and the mapping of expression data to metabolic pathways and chromosome locations have been added to the list of scientific tasks that are being tackled by microarray technology. Each scientific task corresponds to one or more so-called data analysis tasks. Different types of scientific questions require different sets of data analytical techniques. Broadly speaking, there are two classes of elementary data analysis tasks, predictive modeling and pattern-detection. Predictive modeling tasks are concerned with learning a classification or estimation function, whereas pattern-detection methods screen the available data for interesting, previously unknown regularities or relationships.

DNA microarrays. --- DNA microarrays --- Puces à ADN --- EPUB-LIV-FT SPRINGER-B --- Oligonucleotide Array Sequence Analysis --- Molecular Probe Techniques --- Sequence Analysis --- Nucleic Acid Hybridization --- Microarray Analysis --- Investigative Techniques --- Genetic Techniques --- Microchip Analytical Procedures --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Chemistry Techniques, Analytical --- Animal Biochemistry --- Human Anatomy & Physiology --- Health & Biological Sciences --- Analytical Chemistry Methods --- Analytical Chemistry Techniques --- Analytical Chemistry Method --- Analytical Chemistry Technique --- Chemistry Method, Analytical --- Chemistry Methods, Analytical --- Chemistry Technique, Analytical --- Method, Analytical Chemistry --- Methods, Analytical Chemistry --- Technique, Analytical Chemistry --- Techniques, Analytical Chemistry --- Microchip Analysis --- Analyses, Microchip --- Analysis, Microchip --- Analytical Procedure, Microchip --- Analytical Procedures, Microchip --- Microchip Analytical Procedure --- Procedure, Microchip Analytical --- Procedures, Microchip Analytical --- Micromanipulation --- Nanotechnology --- Lab-On-A-Chip Devices --- Genetic Technic --- Genetic Technics --- Genetic Technique --- Technic, Genetic --- Technics, Genetic --- Technique, Genetic --- Techniques, Genetic --- Genetics --- Genetic Counseling --- Genetic Phenomena --- Investigative Technics --- Investigative Technic --- Investigative Technique --- Technic, Investigative --- Technics, Investigative --- Technique, Investigative --- Techniques, Investigative --- Microarray Analytical Devices --- Microarray Microchips --- Nanoarray Analytical Devices --- Analysis, Microarray --- Analytical Device, Microarray --- Analytical Device, Nanoarray --- Analytical Devices, Microarray --- Analytical Devices, Nanoarray --- Device, Microarray Analytical --- Device, Nanoarray Analytical --- Devices, Microarray Analytical --- Devices, Nanoarray Analytical --- Microarray Analytical Device --- Microarray Microchip --- Microchip, Microarray --- Microchips, Microarray --- Nanoarray Analytical Device --- Genomic Hybridization --- Acid Hybridization, Nucleic --- Acid Hybridizations, Nucleic --- Genomic Hybridizations --- Hybridization, Genomic --- Hybridization, Nucleic Acid --- Hybridizations, Genomic --- Hybridizations, Nucleic Acid --- Nucleic Acid Hybridizations --- DNA --- Nucleic Acid Probes --- Oligonucleotide Probes --- Analysis, Sequence --- Determination, Sequence --- Determinations, Sequence --- Sequence Determinations --- Sequence Determination --- Analyses, Sequence --- Sequence Analyses --- Molecular Probe Technic --- Molecular Probe Technics --- Molecular Probe Technique --- Technic, Molecular Probe --- Technics, Molecular Probe --- Technique, Molecular Probe --- Techniques, Molecular Probe --- Probe Technic, Molecular --- Probe Technics, Molecular --- Probe Technique, Molecular --- Probe Techniques, Molecular --- DNA Arrays --- DNA Chips --- DNA Microchips --- Gene Chips --- Oligodeoxyribonucleotide Array Sequence Analysis --- Oligonucleotide Microarrays --- Sequence Analysis, Oligonucleotide Array --- cDNA Arrays --- DNA Microarrays --- Oligonucleotide Arrays --- cDNA Microarrays --- Array, DNA --- Array, Oligonucleotide --- Array, cDNA --- Arrays, DNA --- Arrays, Oligonucleotide --- Arrays, cDNA --- Chip, DNA --- Chip, Gene --- Chips, DNA --- Chips, Gene --- DNA Array --- DNA Chip --- DNA Microarray --- DNA Microchip --- Gene Chip --- Microarray, DNA --- Microarray, Oligonucleotide --- Microarray, cDNA --- Microarrays, DNA --- Microarrays, Oligonucleotide --- Microarrays, cDNA --- Microchip, DNA --- Microchips, DNA --- Oligonucleotide Array --- Oligonucleotide Microarray --- cDNA Array --- cDNA Microarray --- Combinatorial Chemistry Techniques --- Gene Expression Profiling --- DNA biochips --- Biochips --- Immobilized nucleic acids --- methods