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Les biofilms dentaires sont la cause principale des parimplantites, une maladie inflammatoire autour des implants dentaires. Le biofilm est une organisation spécifique de bactéries qui lui permet d’acquérir une résistance aux agents antimicrobiens et d’être la cause de nombreux échecs thérapeutiques. Par conséquent, les approches classiques semblent dépassées et le développement de nouvelles procédures apparait dès lors nécessaire afin d’améliorer le traitement des maladies parodontales. Objectifs : Déterminer la capacité ou non d’un courant électrique de 5mA à potentialiser l’effet antibactérien d’un antiseptique appliqué ex-vivo à un biofilm dentaire formé in vivo sur des surfaces en titane. Matériels et méthodes : Lors des expériences, des biofilms dentaires ont été formés par quatre volontaires via le port de gouttières garnies de 10 pastilles de titane. Après 24 heures de maturation, les pastilles ont été traitées en deux groupes. Les cinq premières par la chlorhexidine 0,2% seule et les cinq autres par un couplage chlorhexidine 0,2% et courant continu de 5Ma. La diminution des bactéries a ensuite été déterminée pour les temps 0,30 secondes, 1, 2 et 5 minutes. Cette même expérience a été réalisée en utilisant le PBS, nous servant de contrôle. Résultat : il n’y a pas de différences significatives (p>0,05) entre les deux groupes (CHX et CHX +5mA). Néanmoins, les résultats sont non négligeables et l’application d’un courant électrique s’avère prometteur et vaut la peine d’être étudié plus profondément.

Chlorhexidine --- Electric Stimulation Therapy --- Biofilms --- Dental Deposits

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Dental calculus. --- Biomineralization. --- Biological mineralization --- Mineralization, Biological --- Minerals in the body --- Calculus, Dental --- Tartar (Dentistry) --- Dental deposits --- Dental prophylaxis

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Biofilms --- Microbiology --- Microorganisms --- Microbial ecology --- Biofilms. --- Microbiological Phenomena. --- Microbial ecology. --- Microbiology. --- Microorganisms. --- Germs --- Micro-organisms --- Microbes --- Microscopic organisms --- Organisms --- Microbial biology --- Biology --- Environmental microbiology --- Ecology --- Microbial aggregation --- Microbial Concepts --- Microbial Phenomena --- Microbiologic Concepts --- Microbiological Phenomenon --- Microbiological Process --- Phenomena, Microbiologic --- Microbiologic Phenomena --- Microbiological Processes --- Concept, Microbial --- Concept, Microbiologic --- Concepts, Microbial --- Concepts, Microbiologic --- Microbial Concept --- Microbiologic Concept --- Phenomena, Microbial --- Phenomena, Microbiological --- Phenomenon, Microbiological --- Process, Microbiological --- Processes, Microbiological --- Dysbiosis --- Biofilm --- Dental Deposits --- Prosthesis-Related Infections --- Adhesins, Bacterial --- Biofouling --- biofilms --- microbiomes --- viromes --- phageomes --- mycomes --- fungomes --- General microbiology --- General ecology and biosociology

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Human tissues often support large, complex microbial communities growing as biofilms that can cause a variety of infections. As a result of an increased use of implanted medical devices, the incidence of these biofilm-associated diseases is increasing: the non-shedding surfaces of these devices provide ideal substrata for colonisation by biofilm-forming microbes. The consequences of this mode of growth are far-reaching. As microbes in biofilms exhibit increased tolerance towards antimicrobial agents and decreased susceptibility to host defence systems, biofilm-associated diseases are becoming increasingly difficult to treat. Not surprisingly, therefore, interest in biofilms has increased dramatically. The application of microscopic and molecular techniques has revolutionised our understanding of biofilm structure, composition, organisation, and activities, resulting in important advances in the prevention and treatment of biofilm-related diseases. The purpose of this book, which was first published in 2003, is to bring these advances to the attention of clinicians and medical researchers.

Biofilms. --- Food -- Microbiology. --- Food -- Safety measures. --- Food Industry. --- Medical microbiology. --- Biofilms --- Medical microbiology --- Prosthesis-Related Infections --- Infection --- Postoperative Complications --- Microbiological Phenomena --- Pathologic Processes --- Phenomena and Processes --- Bacterial Infections and Mycoses --- Diseases --- Pathological Conditions, Signs and Symptoms --- Microbiology & Immunology --- Biology --- Health & Biological Sciences --- Symptoms and General Pathology --- Pathological Processes --- Processes, Pathologic --- Processes, Pathological --- Microbial Concepts --- Microbial Phenomena --- Microbiologic Concepts --- Microbiological Phenomenon --- Microbiological Process --- Phenomena, Microbiologic --- Microbiologic Phenomena --- Microbiological Processes --- Concept, Microbial --- Concept, Microbiologic --- Concepts, Microbial --- Concepts, Microbiologic --- Microbial Concept --- Microbiologic Concept --- Phenomena, Microbial --- Phenomena, Microbiological --- Phenomenon, Microbiological --- Process, Microbiological --- Processes, Microbiological --- Dysbiosis --- Complication, Postoperative --- Complications, Postoperative --- Postoperative Complication --- Surgical Procedures, Operative --- Infection and Infestation --- Infections and Infestations --- Infestation and Infection --- Infestations and Infections --- Biofilm --- Dental Deposits --- Adhesins, Bacterial --- Biofouling --- Infections, Prosthesis-Related --- Prosthesis Related Infection --- Prosthesis-Related Infection --- Infection, Prosthesis Related --- Prosthesis Related Infections --- Related Infection, Prosthesis --- Related Infections, Prosthesis --- Microbial aggregation --- Microbial ecology