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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact

Civil engineering, surveying & building --- Mechanical engineering & materials --- topological constraint theory (TCT) --- topological phases --- fragility index --- modulated-DSC --- molecular dynamics --- Raman scattering --- chalcogenides --- statistical mechanics

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The building industry is influenced by many factors and trends reflecting the current situation and developments in social, economic, technical, and scientific fields. One of the most important trends seeks to minimize the energy demand. This can be achieved by promoting the construction of buildings with better thermal insulating capabilities of their envelopes and better efficiency in heating, ventilation, and air conditioning systems. Any credible assessment of building energy performance includes the identification and simulation of heat and mass transfer phenomena in both the building envelope and the interior of the building. As the interaction between design elements, climate change, user behavior, heating effectiveness, ventilation, air conditioning systems, and lighting is not straightforward, the assessment procedure can present a complex and challenging task. The simulations should then involve all factors affecting the energy performance of the building in questions. However, the appropriate choice of physical model of heat and mass transfer for different building elements is not the only factor affecting the output of building energy simulations. The accuracy of the material parameters applied in the models as input data is another potential source of uncertainty. For instance, neglecting the dependence of hygric and thermal parameters on moisture content may affect the energy assessment in a significant way. Boundary conditions in the form of weather data sets represent yet another crucial factor determining the uncertainty of the outputs. In light of recent trends in climate change, this topic is vitally important. This Special Issue aims at providing recent developments in laboratory analyses, computational modeling, and in situ measurements related to the assessment of building energy performance based on the proper identification of heat and mass transfer processes in building structures.

CFD --- thermal performance --- Metamodeling --- carbon black --- energy balance --- XRD --- air terminal device --- Hygrothermal assessment --- thermal energy storage --- fibrous aerogel --- Probabilistic assessment --- natural ventilation --- thermal properties --- DSC --- advanced personalized ventilation --- temperature --- noise level --- geopolymers --- elevation --- plaster --- relative humidity --- air velocity --- ground-granulated blast-furnace slag --- heat treatment --- turbulence --- phase change temperature --- energy saving --- mechanical properties --- building envelope --- SEM --- Time series modelling --- self-heating --- mass flow rate prediction --- thermal conductivity --- Convolutional neural networks --- single-sided --- correlation function

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The need to reduce the ecological footprint of water/land/air vehicles in this era of climate change requires pushing the limits regarding the development of lightweight structures and materials. This requires a thorough understanding of their thermomechanical behavior at several stages of the production chain. Moreover, during service, the response of lightweight alloys under the simultaneous influence of mechanical loads and temperature can determine the lifetime and performance of a multitude of structural components. The present Special Issue, comprising eight original research articles, is dedicated to disseminating current efforts around the globe aimed at advancing understanding of the thermomechanical behavior of structural lightweight alloys under processing or service conditions.

n/a --- microstructure --- strength --- X-ray diffraction --- 7003 alloy --- in situ synchrotron radiation diffraction --- 3D microstructure --- materials modelling --- zinc addition --- tensile test --- connectivity --- DSC --- in-situ tensile deformation --- wire fabrication --- magnesium alloys --- welding --- alloying --- AlMgSi alloy --- LPSO-phase --- mechanical properties --- Mg-Nd-Zn alloys --- thermomechanical treatment --- Cast Al-Si alloys --- EN AW-6082 --- 3D characterization --- damage --- dislocations --- dynamic recrystallization --- powder metallurgy --- aluminum welding --- recovery --- corrosion resistance --- recrystallisation --- numerical simulation --- second phases --- digital image correlation --- ECAP --- aluminum nanocomposites --- deformation behaviour --- thermo-mechanical analysis --- neodymium --- aluminium alloy --- TIG fillers --- electrical conductivity --- TEM --- synchrotron tomography

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This book focuses on the design of polymeric delivery systems for biomedical and nanomedicine applications as well as on understanding how such biomaterials interact in the physiological environment. The reader will find an encompassing view on the state-of-the-art of polymeric carriers, showing how current research deals with new stimuli-responsive systems for cancer therapies and biomedical challenges, namely overcoming the skin barrier. The published papers cover topics ranging from novel production methods and insights on hybrid polymers to applications as diverse as nanoparticles, hydrogels and microneedles for antifungal skin therapy, peptide and siRNA delivery, enhanced skin absorption of bioactive molecules, and anticancer therapy. The book comprises one review paper and nine research papers.

Technology: general issues --- osteoarthritis --- monosodium iodoacetate --- p47phox --- PLGA nanoparticles --- reactive oxygen species --- full factorial design --- optimization --- metronidazole --- nanocomposites --- sodium alginate --- chitosan --- PLGA --- hybrid polymers --- chitosan-PLGA polymer --- NMR --- DSC --- FT-IR --- covalent drug conjugation --- therapeutic nanodevice --- polymeric nanoparticles --- cancer therapy --- controlled drug delivery --- redox responsive PEG-block-PLA --- nanocarriers --- disulfide bond --- controlled release --- retinol --- nanosponge --- hydrogel --- Box–Behnken design --- pharmacokinetic --- terbinafine hydrogel --- niacinamide --- polyethene glycol (PEG) 400 --- solvent --- dermal delivery --- finite dose --- porcine skin --- dissolving microneedles --- multiple sclerosis --- PLP --- transdermal delivery --- tyrosol --- nanoparticles --- Design of Experiment (DoE) --- β cyclodextrin --- DNA binding --- glyconanoparticles --- immunotherapy --- infectious diseases --- mannose receptors --- nutraceuticals --- n/a --- Box-Behnken design

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The demand for aluminum alloys is increasing because of their lightness, high specific strength and other attractive properties, which can exploited in improved products for a greener environment. This book gives a correlation between the processing, microstructure and properties of several aluminium alloys. Some of them are well established and used in an enormous number of applications, while others are still under development. The processing spans from casting, rapid solidification, additive manufacturing, forming, heat-treatment and welding, which can produce interesting microstructures and a useful combination of properties.

Al alloy --- laser induced arc hybrid welding --- heat treatment --- microstructure --- wrought aluminium alloy --- homogenization annealing --- thermodynamic equilibrium --- intermetallic phases --- differential scanning calorimetry (DSC) --- characterization methods --- scalability --- mechanical properties --- aluminium alloys --- aluminium --- ageing --- quasicrystal --- transmission electron microscopy --- aluminium alloy --- SLM --- auxetic structures --- numerical analysis --- fatigue --- Al alloy 7075-T6 --- ultrasonic fatigue --- artificial pits --- pre-corrosion --- crack initiation --- 7xxx aluminum series --- early precipitation stages --- corrosion --- Al3(Sc,Zr) particles --- annihilation of positrons --- activation energy --- material flow --- asymmetric weld --- tensile strength --- VPPA --- aluminum alloy AA5083 --- rapid solidification --- melt spinning --- high-strength aluminum --- extrusion --- bimodal microstructure --- precipitations