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The application properties and the final coating properties of waterborne polymer dispersions are poor compared to the ones of polymer solutions with organic solvents. This is expressed by a short open time and by inhomogeneities and defects that are visible in the final dry coating.Aim of this work is an investigation and discussion of the different aspects that are responsible for the poor application and coating properties of aqueous latex dispersions by experiments and model calculations.

open time --- polymer dispersions --- film formation --- drying --- Raman spectroscopy

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Sugars --- Fluids --- Dispersions --- Crystallization --- Refrigeration. --- Refrigeration --- ice --- Heat treatment

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Trichoderma --- Fungal spores --- Biological control --- formulations --- Theobroma cacao --- Phytophthora --- Dispersions --- Emulsions. --- Emulsions --- Microbial pesticides

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Soybeans. --- Soybeans --- chemical structure --- Adsorption --- Dispersions --- Phospholipids --- chemical reactions --- water --- HPLC --- Liposomes (organelles) --- Reactiekinetiek --- Soya fosfolipiden --- Micelle

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Amorphous solid dispersion (ASD) is a powerful formulation technology to improve oral absorption of poorly soluble drugs. Despite their being in existence for more than half a century, controlling ASD performance is still regarded as difficult because of ASD’s natural non-equilibrium. However, recent significant advances in ASD knowledge and technology may enable a much broader use of ASD technology. This Special Issue, which includes 3 reviews and 6 original articles, focuses on recent progresses in ASD technology in hopes of helping to accelerate developmental studies in the pharmaceutical industry. In striving for a deep understanding of ASD non-equilibrium behavior, the Special issue also delves into and makes progress in the theory of soft-matter dynamics.

thermodynamic modeling --- molecular dynamics simulation --- poorly soluble drugs --- amorphous solid dispersions --- dissolution enhancement --- crystallization tendency --- continuous processing --- stability --- milling --- granulation --- thermal analysis --- amorphous --- ball milling --- pharmaceutical glass --- dissolution --- rebamipide --- poloxamer --- classification --- polyelectrolytes --- amorphisation --- self-assembly --- dissolution rate --- miscibility --- bioavailability --- solubility --- evaporation --- mesoporous --- polyelectrolyte excipient matrix --- polymer --- bicaludamide --- phase diagram --- Weibull dissolution model --- spectroscopic techniques --- anticancer drugs --- manufacturing methods --- nucleation --- molecular complex --- nanoaggregates --- enrofloxacin --- accelerated stability test --- solubility enhancement --- amorphous solid dispersion --- tadalafil --- process development --- amorphous polymeric salt --- Wood’s apparatus --- hot melt extrusion --- solid dispersions --- intrinsic dissolution rate --- solid dispersion --- interaction --- crystallization --- spray drying --- characterization --- ciprofloxacin