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This detailed book collects methods based on the evolution of the chromosome conformation capture (3C) technique and other complementary approaches to dissect chromatin conformation with an emphasis on dissection of nuclear compartmentalization and visualization in imaging. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Capturing Chromosome Conformation: Methods and Protocols serves as an ideal guide for researchers working to further understand 3D genome organization.

Biologia computacional --- Cromosomes humans --- Cromosomes --- Genètica humana --- Genoma humà --- Cromosoma 15 humà --- Biologia --- Biologia de sistemes --- Neurociència computacional --- Bioinformàtica --- Biology—Technique. --- Cytology. --- Genetics. --- Biological Techniques. --- Cell Biology. --- Genetics and Genomics. --- Cell biology --- Cellular biology --- Biology --- Cells --- Embryology --- Mendel's law --- Adaptation (Biology) --- Breeding --- Chromosomes --- Heredity --- Mutation (Biology) --- Variation (Biology)

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Plant genetics. --- Functional genomics. --- RNA. --- Ribonucleic acid --- Ribose nucleic acid --- Nucleic acids --- Ribose --- Physiological genomics --- Genomics --- Physiology --- Plants --- Genetics --- Genètica vegetal --- Fitogenètica --- Genètica de les plantes --- Genètica --- Genètica molecular vegetal --- Nombre de cromosomes de les plantes --- Millorament selectiu de plantes

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Sesame. --- Beniseed --- Orientale sesame --- Sesamum indicum --- Sesamum orientale --- Oilseed plants --- Sesamum --- Genètica vegetal --- Fitogenètica --- Genètica de les plantes --- Genètica --- Genètica molecular vegetal --- Nombre de cromosomes de les plantes --- Millorament selectiu de plantes

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"Encompasses all aspects of chromosome biology and the application of molecular cytogenetic techniques in all areas of biomedicine."

Cytogenetics --- Chromosomes --- Molecular Biology --- Molecular genetics --- Cytogénétique --- Génétique moléculaire --- Periodicals. --- Périodiques --- Cytogenetics. --- Chromosomes. --- Biochemical Phenomena. --- Molecular genetics. --- Chromosome theory --- Biochemical Concepts --- Biochemical Phenomenon --- Biochemical Process --- Phenomena, Biochemical --- Biochemical Processes --- Biochemical Concept --- Concept, Biochemical --- Concepts, Biochemical --- Phenomenon, Biochemical --- Process, Biochemical --- Processes, Biochemical --- Chromosome --- Cytogenetic --- chromosome biology --- medical genetics --- Genetics --- Molecular biology --- Cytology --- Cell nuclei --- Crossing over (Genetics) --- Cytotaxonomy --- Karyokinesis --- Linkage (Genetics) --- Cytogenetic Analysis --- Chromosome Disorders --- Sex Chromosome Disorders --- moleculaire biologie --- Citogenètica. --- Cromosomes. --- Genètica molecular. --- Biologia molecular. --- Biofísica molecular --- Bioquímica molecular --- Biofísica --- Bioquímica --- Histoquímica --- Biologia molecular vegetal --- Codi genètic --- Diagnòstic molecular --- Endocrinologia molecular --- Evolució molecular --- Farmacologia molecular --- Genètica molecular --- Glicòmica --- Metabolòmica --- Microbiologia molecular --- Neurobiologia molecular --- Patologia molecular --- Proteòmica --- Reconeixement molecular --- Biomolècules --- Biologia molecular --- Genètica --- Clonatge molecular --- Elements genètics mòbils --- Genètica bioquímica --- Genètica molecular humana --- Genètica molecular vegetal --- Genòmica --- Gens --- Regulació genètica --- Variació en el nombre de còpies --- Herència (Biologia) --- Nuclis cel·lulars --- Anomalies cromosòmiques --- Al·lelomorfisme --- Cariotips --- Cromatina --- Cromosomes humans --- Cromosomes sexuals --- Recombinació genètica --- Telòmer --- Translocació (Genètica) --- Genètica cel·lular --- Citologia --- Citogenètica humana --- Mapatge cromosòmic --- Citogenètica --- Cromosomes

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This book describes the current state of international grape genomics, with a focus on the latest findings, tools and strategies employed in genome sequencing and analysis, and genetic mapping of important agronomic traits. It also discusses how these are having a direct impact on outcomes for grape breeders and the international grape research community. While V. vinifera is a model species, it is not always appreciated that its cultivation usually requires the use of other Vitis species as rootstocks. The book discusses genetic diversity within the Vitis genus, the available genetic resources for breeding, and the available genomic resources for other Vitis species. Grapes (Vitis vinifera spp. vinifera) have been a source of food and wine since their domestication from their wild progenitor (Vitis vinifera ssp. sylvestris) around 8,000 years ago, and they are now the world’s most valuable horticultural crop. In addition to being economically important, V. vinifera is also a model organism for the study of perennial fruit crops for two reasons: Firstly, its ability to be transformed and micropropagated via somatic embryogenesis, and secondly its relatively small genome size of 500 Mb. The economic importance of grapes made V. vinifera an obvious early candidate for genomic sequencing, and accordingly, two draft genomes were reported in 2007. Remarkably, these were the first genomes of any fruiting crop to be sequenced and only the fourth for flowering plants. Although riddled with gaps and potentially omitting large regions of repetitive sequences, the two genomes have provided valuable insights into grape genomes. Cited in over 2,000 articles, the genome has served as a reference in more than 3,000 genome-wide transcriptional analyses. Further, recent advances in DNA sequencing and bioinformatics are enabling the assembly of reference-grade genome references for more grape genotypes revealing the exceptional extent of structural variation in the species.

Plant genetics. --- Plant breeding. --- Agriculture. --- Plant Genetics and Genomics. --- Plant Breeding/Biotechnology. --- Farming --- Husbandry --- Industrial arts --- Life sciences --- Food supply --- Land use, Rural --- Crops --- Agriculture --- Breeding --- Plants --- Genetics --- Grapes --- Genetics. --- Grape --- Grape vines --- Grapevines --- Vitis --- Wine grapes --- Vitaceae --- Enocyanin --- Viticulture --- Genètica vegetal --- Fitogenètica --- Genètica de les plantes --- Genètica --- Genètica molecular vegetal --- Nombre de cromosomes de les plantes --- Millorament selectiu de plantes