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Medical genetics --- Genetics, Medical. --- Medical genetics. --- Human Genetics --- Medical Genetics --- Genetics, Human --- Clinical genetics --- Diseases --- Heredity of disease --- Genetic aspects --- Genetics, Medical --- Human genetics --- Medical sciences --- Pathology --- Genetic disorders --- Anthropology, Physical --- Chromosome Disorders --- Sex Chromosome Disorders --- Genetic Diseases, Inborn --- Molecular Medicine --- Genètica mèdica. --- Genètica humana --- Patologia --- Farmacogenètica --- Genètica veterinària --- Toxicologia genètica --- Consell genètic --- Cribratge genètic --- Malalties hereditàries --- Genetics

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This volume provides clear and direct protocols to implement automated Design-Build-Test-Learn (DBTL) into synthetic biology research. Chapters detail techniques to model and simulate biological systems, redesign biological systems, setting up of an automated biolaboratory, step-by-step guide on how to perform computer aided design, RNA sequencing, microfluidics -using bacterial cell free extracts, live mammalian cells, computational and experimental procedures, metabolic burden, computational techniques to predict such burden from models, and how DNA parts can be engineered in mammalian cells to sense, and respond to, and intracellular signals in general. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Synthetic Gene Circuits: Methods and Protocols aims to ensure successful results in the further study of this vital field.

Bioenginyeria --- Biologia computacional --- Biologia --- Biologia de sistemes --- Neurociència computacional --- Bioinformàtica --- Enginyeria biològica --- Enginyeria --- Enginyeria biomèdica --- Biònica --- Biotelemetria --- Enginyeria agronòmica --- Guerra biològica --- Medical genetics. --- Biotechnology. --- Biology—Technique. --- Medical Genetics. --- Biological Techniques. --- Chemical engineering --- Genetic engineering --- Clinical genetics --- Diseases --- Heredity of disease --- Human genetics --- Medical sciences --- Pathology --- Genetic disorders --- Genetic aspects --- Genètica mèdica --- Genètica humana --- Patologia --- Farmacogenètica --- Genètica veterinària --- Toxicologia genètica --- Consell genètic --- Cribratge genètic --- Malalties hereditàries