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Hypericum extract preparations are used extensively in many countries to treat mildly to moderately depressed patients. While this was based previously on traditional experience, extensive research over the last 10 years has given a broad preclinical and clinical basis to justify the use of Hypericum as an antidepressant. This book reviews the available data related to the biochemical, functional, and behavioural pharmacology of Hypericum and its active constituents. The clinical chapters overview the evidenced basis for its use as an antidepressant, initial data in anxiety and somatoform disorders, and the site effect profile of Hypericum and its possible relevant drug interactions. The known pharmacokinetics of the relevant constituents and the biopharmaceutical quality of commercially available Hypericum preparations are also discussed.
Hypericum perforatum --- Affective disorders --- Therapeutic use. --- Treatment. --- Disorders, Affective --- Mood disorders --- Psychology, Pathological --- Common Saint Johnswort --- Klamath weed --- Perforate Saint Johnswort --- Saint Johns-wort, Common --- Saint Johnswort, Common --- St. Johnswort, Common --- Tipton's weed --- Hypericum --- Toxicology. --- Neurosciences. --- Neurology. --- Psychiatry. --- Psychotherapy. --- Biochemistry. --- Pharmacology/Toxicology. --- Plant Biochemistry. --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Biology --- Chemistry --- Medical sciences --- Psychagogy --- Therapy (Psychotherapy) --- Mental illness --- Clinical sociology --- Mental health counseling --- Medicine and psychology --- Mental health --- Medicine --- Nervous system --- Neuropsychiatry --- Neural sciences --- Neurological sciences --- Neuroscience --- Chemicals --- Pharmacology --- Poisoning --- Poisons --- Composition --- Treatment --- Diseases --- Toxicology --- Pharmacology. --- Neurology . --- Psychotherapy . --- Plant biochemistry. --- Phytochemistry --- Plant biochemistry --- Plant chemistry --- Biochemistry --- Botany --- Phytochemicals --- Plant biochemical genetics --- Drug effects --- Medical pharmacology --- Chemotherapy --- Drugs --- Pharmacy --- Physiological effect
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Depression, Mental --- Hypericum perforatum --- Depressive Disorder --- Xanthenes --- Plant Extracts --- Perylene --- Depression --- Benz(a)Anthracenes --- Mood Disorders --- Behavioral Symptoms --- Plant Preparations --- Pharmaceutical Preparations --- Heterocyclic Compounds, 3-Ring --- Phenalenes --- Polycyclic Hydrocarbons, Aromatic --- Chemicals and Drugs --- Behavior --- Biological Products --- Mental Disorders --- Heterocyclic Compounds --- Psychiatry and Psychology --- Polycyclic Compounds --- Hydrocarbons, Aromatic --- Behavior and Behavior Mechanisms --- Complex Mixtures --- Hydrocarbons, Cyclic --- Hydrocarbons --- Organic Chemicals --- Psychiatric Disorders, Individual --- Psychiatry --- Health & Biological Sciences --- Alternative treatment --- Therapeutic use --- Pharmaceutical Preparations. --- Psychiatry. --- Organic Chemical --- Chemical, Organic --- Chemicals, Organic --- Hydrocarbon --- Saturated Hydrocarbons --- Unsaturated Hydrocarbons --- Hydrocarbons, Saturated --- Hydrocarbons, Unsaturated --- Cyclic Hydrocarbons --- Hydrocarbons, Polycyclic --- Polycyclic Hydrocarbons --- Complex Extracts --- Crude Extracts --- Extracts, Complex --- Extracts, Crude --- Complex Extract --- Complex Mixture --- Crude Extract --- Mixtures, Complex --- Extract, Complex --- Extract, Crude --- Mixture, Complex --- Behavior And Behavior Mechanism --- Aromatic Hydrocarbon --- Aromatic Hydrocarbons --- Hydrocarbon, Aromatic --- Compounds, Polycyclic --- Psychiatrists --- Psychiatrist --- Heterocyclic Compound --- Compound, Heterocyclic --- Compounds, Heterocyclic --- Behavior Disorders --- Diagnosis, Psychiatric --- Mental Disorders, Severe --- Psychiatric Diagnosis --- Mental Illness --- Psychiatric Diseases --- Psychiatric Disorders --- Psychiatric Illness --- Illness, Mental --- Mental Disorder --- Mental Disorder, Severe --- Mental Illnesses --- Psychiatric Disease --- Psychiatric Disorder --- Psychiatric Illnesses --- Severe Mental Disorder --- Severe Mental Disorders --- Mentally Ill Persons --- Biologic Drugs --- Biologic Medicines --- Biologic Pharmaceuticals --- Biologic Products --- Biological Drugs --- Biological Medicines --- Biologicals --- Biopharmaceuticals --- Products, Biological --- Biologic --- Biologic Drug --- Biologic Product --- Biological --- Biological Drug --- Biological Medicine --- Biological Product --- Biologics --- Biopharmaceutical --- Natural Product --- Natural Products --- Drug, Biologic --- Drug, Biological --- Drugs, Biologic --- Drugs, Biological --- Medicine, Biological --- Medicines, Biologic --- Medicines, Biological --- Pharmaceuticals, Biologic --- Product, Biologic --- Product, Biological --- Product, Natural --- Biological Factors --- Acceptance Process --- Acceptance Processes --- Behaviors --- Process, Acceptance --- Processes, Acceptance --- Pharmaceutic Preparations --- Pharmaceutical Products --- Pharmaceuticals --- Preparations, Pharmaceutical --- Drug --- Drugs --- Pharmaceutical --- Pharmaceutical Preparation --- Pharmaceutical Product --- Preparation, Pharmaceutical --- Preparations, Pharmaceutic --- Product, Pharmaceutical --- Products, Pharmaceutical --- Pharmacology --- Drug Dosage Calculations --- Polycyclic Aromatic Hydrocarbon --- Polynuclear Aromatic Hydrocarbon --- Polynuclear Aromatic Hydrocarbons --- Aromatic Hydrocarbon, Polycyclic --- Aromatic Hydrocarbon, Polynuclear --- Aromatic Hydrocarbons, Polycyclic --- Aromatic Hydrocarbons, Polynuclear --- Aromatic Polycyclic Hydrocarbons --- Hydrocarbon, Polycyclic Aromatic --- Hydrocarbon, Polynuclear Aromatic --- Hydrocarbons, Aromatic Polycyclic --- Hydrocarbons, Polycyclic Aromatic --- Hydrocarbons, Polynuclear Aromatic --- Fused-Ring Compounds --- Bridged-Ring Compounds --- Oxabenzochrysenones --- Phenylphenalenones --- Fused Heterocyclic Compounds, Three-Ring --- Heterocyclic Cpds, 3 Ring --- Three Ring Heterocyclic Compounds --- 3-Ring Heterocyclic Compounds --- Fused Heterocyclic Compounds, Three Ring --- Heterocyclic Compounds, 3 Ring --- Herbal Preparation --- Plant Preparation --- Herbal Preparations --- Preparation, Plant --- Behavioral Symptom --- Symptom, Behavioral --- Symptoms, Behavioral --- Affective Disorders --- Affective Disorder --- Disorder, Affective --- Disorder, Mood --- Disorders, Affective --- Disorders, Mood --- Mood Disorder --- Benz(b)Phenanthrenes --- Naphthanthracenes --- Emotional Depression --- Depressive Symptoms --- Depression, Emotional --- Depressive Symptom --- Symptom, Depressive --- Peri-Dinaphthalene --- Perilene --- Peri Dinaphthalene --- Herbal Medicines --- Plant Extract --- Extract, Plant --- Extracts, Plant --- Medicines, Herbal --- Materia Medica --- Phytotherapy --- Plants, Medicinal --- Herbal Medicine --- Xanthene --- Depression, Endogenous --- Depression, Neurotic --- Depression, Unipolar --- Depressive Syndrome --- Melancholia --- Neurosis, Depressive --- Unipolar Depression --- Depressions, Endogenous --- Depressions, Neurotic --- Depressions, Unipolar --- Depressive Disorders --- Depressive Neuroses --- Depressive Neurosis --- Depressive Syndromes --- Disorder, Depressive --- Disorders, Depressive --- Endogenous Depression --- Endogenous Depressions --- Melancholias --- Neuroses, Depressive --- Neurotic Depression --- Neurotic Depressions --- Syndrome, Depressive --- Syndromes, Depressive --- Unipolar Depressions --- Common Saint Johnswort --- Klamath weed --- Perforate Saint Johnswort --- Saint Johns-wort, Common --- Saint Johnswort, Common --- St. Johnswort, Common --- Tipton's weed --- Hypericum --- Depressive Disorder. --- Xanthenes. --- Plant Extracts. --- Perylene. --- Depression. --- Benz(a)Anthracenes. --- Mood Disorders. --- Behavioral Symptoms. --- Plant Preparations. --- Heterocyclic Compounds, 3-Ring. --- Phenalenes. --- Polycyclic Aromatic Hydrocarbons. --- Behavior. --- Biological Products. --- Mental Disorders. --- Heterocyclic Compounds. --- Polycyclic Compounds. --- Hydrocarbons, Aromatic. --- Behavior and Behavior Mechanisms. --- Complex Mixtures. --- Hydrocarbons, Cyclic. --- Hydrocarbons. --- Organic Chemicals. --- Alternative treatment. --- Therapeutic use.
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