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This book aims at providing insights into the collagen superfamily and the remarkable diversity of collagen function within the extracellular matrix. Additionally, the mechanisms underlying collagen-related diseases such as dystrophic epidermolysis bullosa, osteogenesis imperfecta, as well as collagen-related myopathies and neurological disorders are discussed. Collagens are the most abundant extracellular matrix proteins in organisms. Their primary function is to provide structural support and strength to cells and to maintain biomechanical integrity of tissues. However, collagens can no longer be considered just as structural proteins. They can act as extracellular modulators of signaling events and serve critical regulatory roles in various cell functions during embryonic development and adult homeostasis. Furthermore, collagens are associated with a broad spectrum of heritability-related diseases known as “collagenopathies” that affect a multitude of organs and tissues including sensorial organs. The book is a useful introduction to the field for junior scientists, interested in extracellular matrix research. It is also an interesting read for advanced scientists and clinicians working on collagens and collagenopathies, giving them a broader view of the field beyond their area of specialization.

Cell biology. --- Chemistry. --- Human physiology. --- Life sciences. --- Neurosciences. --- Cell Biology. --- Chemistry/Food Science, general. --- Human Physiology. --- Life Sciences, general. --- Neural sciences --- Neurological sciences --- Neuroscience --- Medical sciences --- Nervous system --- Biosciences --- Sciences, Life --- Science --- Human biology --- Physiology --- Human body --- Physical sciences --- Cell biology --- Cellular biology --- Biology --- Cells --- Cytology. --- Col·lagen --- Col·lagenosi --- Citologia

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This book is the second of two volumes that together offer a comprehensive account of cutting-edge advances in the development of biomaterials for use within tissue engineering and regenerative medicine. In this volume, which is devoted to biomimetic biomaterials, the opening section discusses bone regeneration by means of duck’s feet-derived collagen scaffold and the use of decellularized extracellular matrices. The role of various novel biomimetic hydrogels in regenerative medicine is then considered in detail. The third section focuses on the control of stem cell fate by biomimetic biomaterials, covering exosome-integrated biomaterials for bone regeneration, cellular responses to materials for biomedical engineering, and the regulation of stem cell functions by micropatterned structures. Finally, the use of nano-intelligent biocomposites in regenerative medicine is addressed, with discussion of, for example, recent advances in biphasic calcium phosphate bioceramics and blood-contacting polymeric biomaterials. The authors are recognized experts in the interdisciplinary field of regenerative medicine and the book will be of value for all with an interest in regenerative medicine based on biomaterials.

Biomedical materials. --- Tissue engineering. --- Biomimetic materials. --- Materials --- Biomedical engineering --- Regenerative medicine --- Tissue culture --- Biocompatible materials --- Biomaterials --- Medical materials --- Medicine --- Biocompatibility --- Prosthesis --- Biomedical engineering. --- Regenerative medicine. --- Pharmaceutical technology. --- Neurosciences. --- Biochemical engineering. --- Biomedical Engineering/Biotechnology. --- Regenerative Medicine/Tissue Engineering. --- Pharmaceutical Sciences/Technology. --- Biochemical Engineering. --- Bio-process engineering --- Bioprocess engineering --- Biochemistry --- Biotechnology --- Chemical engineering --- Neural sciences --- Neurological sciences --- Neuroscience --- Medical sciences --- Nervous system --- Pharmaceutical laboratory techniques --- Pharmaceutical laboratory technology --- Technology, Pharmaceutical --- Technology --- Regeneration (Biology) --- Clinical engineering --- Medical engineering --- Bioengineering --- Biophysics --- Engineering --- Medicina regenerativa --- Enginyeria biomèdica --- Teixit connectiu --- Teixit conjuntiu --- Aparell locomotor --- Teixits (Histologia) --- Matriu extracel·lular --- Teixit adipós --- Teixit ossi --- Col·lagen --- Lligaments --- Enginyeria clínica --- Enginyeria mèdica --- Bioenginyeria --- Biofísica --- Enginyeria --- Medicina --- Electrònica mèdica --- Enginyeria de teixits --- Materials biomèdics --- Aparells i instruments mèdics --- Regeneració (Biologia)