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Datenqualität in der medizinischen Forschung.
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ISBN: 3954663740 3954661217 Year: 2014 Publisher: Berlin MWV Medizinisch Wissenschaftliche Verlagsgeschellschaft

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The benefit of cohort studies and registers in patient-oriented collaborative research depends largely on the quality of the data recorded there. Supply and quality research depend on scientifically proven methods and procedures to ensure high data quality. This guideline contains corresponding recommendations for the management of data quality in registers, cohort studies and data repositories. In the second edition, a significantly expanded set of indicators is provided and the use of the indicators is described as an example for different types of empirical research projects. The guideline is rounded off by a current literature review and analysis. It is therefore an important part of the range of measures to improve and ensure data quality in medical research.

Life-style and mortality : a large-scale census-based cohort study in Japan
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ISBN: 3805552017 9783805552011 Year: 1990 Volume: 6 Publisher: Basel Karger

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Keywords

Health status indicators --- Lifestyles --- Mortality --- Health surveys --- Health Surveys --- Health aspects --- Mortality. --- Cohort Studies. --- Life Style. --- Health Surveys. --- -Health surveys --- -Japanese --- -Lifestyles --- -Life style --- Life styles --- Styles, Life --- Human behavior --- Manners and customs --- Ethnology --- Public health surveys --- Surveys --- Health indicators --- Health status indexes --- Indexes, Health status --- Indicators, Health status --- Health --- Medical statistics --- Public health --- Quality of life --- Social indicators --- Abortion Surveys --- Abortion Survey --- Health Survey --- Survey, Abortion --- Survey, Health --- Surveys, Abortion --- Surveys, Health --- Life Style Induced Illness --- Lifestyle --- Life Styles --- Quality of Life --- Social Environment --- Analysis, Cohort --- Cohort Studies, Closed --- Cohort Studies, Historical --- Studies, Closed Cohort --- Studies, Concurrent --- Studies, Historical Cohort --- Closed Cohort Studies --- Cohort Analysis --- Concurrent Studies --- Historical Cohort Studies --- Incidence Studies --- Analyses, Cohort --- Closed Cohort Study --- Cohort Analyses --- Cohort Study --- Cohort Study, Closed --- Cohort Study, Historical --- Concurrent Study --- Historical Cohort Study --- Incidence Study --- Studies, Cohort --- Studies, Incidence --- Study, Closed Cohort --- Study, Cohort --- Study, Concurrent --- Study, Historical Cohort --- Study, Incidence --- Age Specific Death Rate --- Age-Specific Death Rate --- Case Fatality Rate --- Decline, Mortality --- Determinants, Mortality --- Differential Mortality --- Excess Mortality --- Mortality Decline --- Mortality Determinants --- Mortality Rate --- Mortality, Differential --- Mortality, Excess --- Death Rate --- Age-Specific Death Rates --- Case Fatality Rates --- Death Rate, Age-Specific --- Death Rates --- Death Rates, Age-Specific --- Declines, Mortality --- Determinant, Mortality --- Differential Mortalities --- Excess Mortalities --- Mortalities --- Mortalities, Differential --- Mortalities, Excess --- Mortality Declines --- Mortality Determinant --- Mortality Rates --- Rate, Age-Specific Death --- Rate, Case Fatality --- Rate, Death --- Rate, Mortality --- Rates, Age-Specific Death --- Rates, Case Fatality --- Rates, Death --- Rates, Mortality --- Disease --- -Methodology --- mortality --- Japan. --- -Mortality --- -Japan. --- Cohort Studies --- Life Style --- Mortality, Law of --- Death --- Demography --- Death (Biology) --- Life style --- Methodology --- Bonin Islands --- CFR Case Fatality Rate --- Crude Death Rate --- Crude Mortality Rate --- Crude Death Rates --- Crude Mortality Rates --- Death Rate, Crude --- Mortality Rate, Crude --- Rate, Crude Death --- Rate, Crude Mortality --- Lifestyle Factors --- Factor, Lifestyle --- Lifestyle Factor --- Sanitary Surveys, Water Supply --- Health status indicators - Japan --- Lifestyles - Health aspects - Japan --- Mortality - Japan --- Health surveys - Japan --- Health Surveys - Japan


Book
Fatty Acids and Cardiometabolic Health
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ISBN: 3038978914 3038978906 Year: 2019 Publisher: MDPI - Multidisciplinary Digital Publishing Institute

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The impact of fat intake on hypercholesterolemia and related atherosclerotic cardiovascular diseases has been studied for decades. However, the current evidence base suggests that fatty acids also influences cardiometabolic diseases through other mechanisms including effects on glucose metabolism, body fat distribution, blood pressure, inflammation, and heart rate. Furthermore, studies evaluating single fatty acids have challenged the simplistic view of shared health effects within fatty acid groups categorized by degree of saturation. In addition, investigations of endogenous fatty acid metabolism, including genetic studies of fatty acid metabolizing enzymes, and the identification of novel metabolically derived fatty acids have further increased the complexity of fatty acids’ health impacts. This Special Issue aims to include original research and up-to-date reviews on genetic and dietary modulation of fatty acids, and the role and function of dietary and metabolically derived fatty acids in cardiometabolic health.


Book
Nutrition, Diet Quality, Aging and Frailty
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ISBN: 3036560661 3036560653 Year: 2022 Publisher: Basel MDPI - Multidisciplinary Digital Publishing Institute

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In the last century, the average life expectancy at birth increased from roughly 45 years in the early 1900s to more than 80 years of age at present. However, living longer is often related to different levels of frailty. There is no curative treatment for frailty—the interventions that have been described as effective to slow or delay the onset of frailty are physical activity and nutritional interventions. Maintaining adequate nutrition status is important to reduce the risk of chronic diseases, many of which are age-related. On the other hand, frailty itself may have a negative effect on eating and, thus, on the nutritional status. This Special Issue, "Nutrition, Diet Quality, Aging and Frailty", addresses the existing knowledge on nutrition regarding the causative factors of frailty and disease due to aging, i.e., strategies for delaying the pathological effects of aging. It consists of twelve peer-reviewed papers covering original research, protocol development, methodological studies, narrative or systematic reviews, and meta-analyses, to better understand these complex relationships.


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Nutrition for Gestational Diabetes
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Year: 2020 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

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Gestational diabetes mellitus (GDM) is one of the most common adverse medical conditions that occurs during pregnancy, and its prevalence is rising as part of a diabetes pandemic. Nutrition plays a key role in GDM, whether (1) as part of an ‘unhealthy’ diet, which contributes to its cause, or (2) as part of changes in dietary intake, which act as the frontline treatment for GDM (sometimes supplemented with exercise and pharmacological intervention). Dietary changes, therefore, can alter the risk of developing GDM in the first place, and once GDM has emerged during pregnancy, dietary changes can mitigate the risk of developing GDM-related complications, such as macrosomia, respiratory distress, hypoglycemia and jaundice in the neonate, pre eclampsia, increased need for caesarean section and placental abruption in the mother. In this Special Issue, we aim to highlight the role of nutrition in the aetiology of GDM, whether directly or indirectly through weight gain and obesity, and in its role as a GDM treatment to lower hyperglycemia and the risk of the aforementioned complications.


Book
Neurogenic Bowel Dysfunction
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Year: 2022 Publisher: Basel MDPI - Multidisciplinary Digital Publishing Institute

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Disorders of the central and peripheral nerve systems have severe effects on gut function. Hence, people who have sustained spinal cord injury and multiple sclerosis, Parkinson’s disease, or spina bifida patients may suffer from severe bowel symptoms, including constipation, incontinence to stools, difficult bowel evacuation, or pain. For the present book, a number of international experts have described how disorders of the nerve system affect bowel function, how to assess and treat bowel symptoms, and how the bacterial composition of the bowel may be affected.


Book
Nutrition for Gestational Diabetes
Author:
Year: 2020 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

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Abstract

Gestational diabetes mellitus (GDM) is one of the most common adverse medical conditions that occurs during pregnancy, and its prevalence is rising as part of a diabetes pandemic. Nutrition plays a key role in GDM, whether (1) as part of an ‘unhealthy’ diet, which contributes to its cause, or (2) as part of changes in dietary intake, which act as the frontline treatment for GDM (sometimes supplemented with exercise and pharmacological intervention). Dietary changes, therefore, can alter the risk of developing GDM in the first place, and once GDM has emerged during pregnancy, dietary changes can mitigate the risk of developing GDM-related complications, such as macrosomia, respiratory distress, hypoglycemia and jaundice in the neonate, pre eclampsia, increased need for caesarean section and placental abruption in the mother. In this Special Issue, we aim to highlight the role of nutrition in the aetiology of GDM, whether directly or indirectly through weight gain and obesity, and in its role as a GDM treatment to lower hyperglycemia and the risk of the aforementioned complications.


Book
Neurogenic Bowel Dysfunction
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Year: 2022 Publisher: Basel MDPI - Multidisciplinary Digital Publishing Institute

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Abstract

Disorders of the central and peripheral nerve systems have severe effects on gut function. Hence, people who have sustained spinal cord injury and multiple sclerosis, Parkinson’s disease, or spina bifida patients may suffer from severe bowel symptoms, including constipation, incontinence to stools, difficult bowel evacuation, or pain. For the present book, a number of international experts have described how disorders of the nerve system affect bowel function, how to assess and treat bowel symptoms, and how the bacterial composition of the bowel may be affected.


Book
Tea in Health and Disease
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ISBN: 3038979872 3038979864 Year: 2019 Publisher: MDPI - Multidisciplinary Digital Publishing Institute

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Tea, made from the leaves of the Camellia senenisis plant, is the second most consumed beverage worldwide after water. Accumulating evidence from cellular, animal, epidemiological and clinical studies have linked tea consumption to various health benefits, such as chemoprevention of cancers, chronic inflammation, heart and liver diseases, diabetes, neurodegenerative diseases, etc. Although such health benefits have not been consistently observed in some intervention trials, positive results from clinical trials have provided direct evidence supporting the cancer-protective effect of green tea. In addition, numerous mechanisms of action have been suggested to contribute to tea’s disease-preventive effects. Furthermore, effects of the processing and storage of tea, as well as additives on tea’s properties have been investigated.


Book
The Impact of Caffeine and Coffee on Human Health
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ISBN: 3039218352 3039218344 Year: 2019 Publisher: MDPI - Multidisciplinary Digital Publishing Institute

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The purpose of this Special Issue is to provide a thorough and up-to-date presentation of research investigating the impact of coffee and/or caffeine intake on various health outcomes. Areas of interest include, but are not limited to, the following topics: Human clinical trials of coffee or caffeine use in relation to disease or intermediate phenotypes. Epidemiological studies of habitual coffee or caffeine intake in relation to human health, among the general public, as well as, among special populations (i.e., children, pregnant women, diabetics, cancer patients, hypertensives, etc.). Mechanisms of action of nutrients and other bioactive components of coffee/caffeine. Studies integrating genetic or physiological markers of coffee/caffeine intake to investigations of coffee and health.

Keywords

coronary artery disease --- n/a --- lipids --- NADH dehydrogenase --- tea --- tinnitus --- safety --- transcriptomics --- ergogenic --- guidelines --- myocardial perfusion --- placebo --- Caffeine --- risk factors --- lysophosphatidylcholine --- pregnancy --- assisted reproduction techniques --- population --- adenosine --- liver fibrosis --- coffee consumption --- cognitive --- causation --- supplement --- mate --- adult --- gene expression --- wine --- lipidomics --- chocolate --- exercise --- protection --- Suicide --- dipyridamole --- regadenoson --- live birth --- hearing --- pharmacological ergogenic aid --- behavior --- cardiovascular disease --- gene-diet interaction --- whole-blood --- sex --- health --- systematic review --- causality --- genetic epidemiology --- implantation --- pharmacogenomics --- cognitions --- ergogenic aid --- time trial performance --- CYP1A2 --- aging --- phenolic --- country --- caffeine intake --- serum chloride levels --- polymorphism --- responders --- intoxication --- trial --- epidemiological methods --- bias --- adenosine receptor --- longevity --- did not respond --- energy drinks --- biomarkers --- individual responses --- Mendelian Randomization --- public policy --- anxiety --- the Norwegian Women and Cancer Cohort (NOWAC) --- ADORA2A --- clinical pregnancy --- caffeine metabolism --- caffeine intoxication --- cohort study --- mood --- mRNA --- alcohol consumption --- epidemiology --- caffeine --- expectancy --- accidental death --- European Prospective Investigation into Cancer and Nutrition --- cognition --- consumption --- HIV-HCV co-infection --- cytochrome P450 --- chlorogenic acids --- soda --- 24-h dietary recall --- coffee --- depression --- sport --- age

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