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Anatomy, Comparative --- Clitoris --- Cloaca (Zoology) --- Generative organs, Female --- Clitoris --- Cloaca --- Sex

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From the Foreword "The experienced surgeon will appreciate this book by recognizing the details and exquisitely rendered images that call to mind similar cases encountered. For the surgeon or trainee relatively new to the practice of colorectal surgery, the graphic presentation of the surgical pathology, with the accompanying succinct and informative text, will make the acquisition of this book a worthwhile one." Victor Fazio, M.D. and Stanley Goldberg, M.D. As Lord Moynihan frequently mentioned in his legendary lectures, surgeons have the unique opportunity to study pathology in vivo, or in a living state. The pathology is seen in relation to normal anatomy, leading to important surgical judgments that ensure only diseased tissue will be removed, and with minimal damage or sacrifice to normal structures. In addition to influencing surgical design making, observation of living pathology offers a glimpse into the disease process and provides a valuable assessment of the morphological features of the specimen before it is preserved with formalin. Colorectal Surgery: Living Pathology in the Operating Room is a unique collection of beautifully illustrated cases focusing on the pathology as much as the operative technique used to remove the diseased tissue. One hundred case reports describe unusual findings, or unusual manifestations of more common conditions, encountered by the author during his 40-plus years in practice as a colorectal surgeon. All of the drawings in the book were sketched immediately after the procedures in order to capture the details and significance of the specimen. As finished drawings, Dr. Killingback’s beautiful images increase the reader’s conceptual knowledge of surgical pathology and how it presents. Accompanying text, photos, and diagnostic studies provide the details of patient management and shed further light on the intrinsic art and science of interpreting living pathology, making this a must-have resource for colorectal surgeons and residents as well as general surgeons and surgical pathologists.

Colon (Anatomy) --- Rectum --- Surgery --- Colorectum --- Cloaca (Zoology) --- Intestine, Large --- Surgery. --- Pathology. --- Colorectal Surgery. --- General Surgery. --- Surgery, Primitive --- Medicine --- Disease (Pathology) --- Medical sciences --- Diseases --- Medicine, Preventive --- Rectum—Surgery .

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Colon (Anatomy) --- Rectum --- Surgery --- Colorectum --- Surgery. --- Colon --- surgery --- Rectums --- Omental Appendices --- Omental Appendix --- Appendix Epiploica --- Taenia Coli --- Appendices, Omental --- Appendix, Omental --- Cloaca (Zoology) --- Intestine, Large --- surgery.

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This book reviews the potential of next-generation sequencing (NGS) in research on and management of colorectal cancer (CRC), a leading cause of death worldwide and one of the most biologically and clinically heterogeneous cancers. It critically discusses findings from recent large-scale studies, clinical trials and meta-analyses and offers an introduction to the management of CRC in the era of precision medicine. In CRC, dozens of driver and passenger mutations are associated with the malignant transformation of epithelial cells. Consequently, the book discusses recent advances in our understanding of the genetics of CRC as a biomarker, the advent of NGS technologies in modern genomics, and the impact of NGS technology on the management of CRC. Furthermore, it highlights the potential of NGS in the context of liquid biopsy and single-cell sequencing in CRC, as well as its role in shedding light on the link between gut microbiota, immune-checkpoint blockade and CRC. The book concludes with a chapter on the limitations and cost-effectiveness of NGS in CRC. Given its scope, the book will appeal to all those interested in learning about the potential of NGS in advancing CRC research and patient care. .

Cancer research. --- Genetics. --- Cancer Research. --- Genetics and Genomics. --- Biology --- Embryology --- Mendel's law --- Adaptation (Biology) --- Breeding --- Chromosomes --- Heredity --- Mutation (Biology) --- Variation (Biology) --- Cancer research --- Rectum --- Colorectal Neoplasms --- Colon (Anatomy) --- Cancer --- Colorectum --- Intestine, Large --- Cloaca (Zoology)

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Laparoscopic Colorectal Surgery, Second Edition is fully revised and updated and reflects an authoritative, team-oriented approach to the latest state-of-the-art laparoscopic colorectal procedures and surgical techniques. Written by pioneers in the field, this text will supply surgeons with all the information necessary to accomplish advanced laparoscopic procedures. Comprehensive discussions of positioning, instrumentation, cannulas, surgical techniques, special considerations, and considerations in cancer surgery are featured for a wide variety of major operative procedures. This new Second Edition includes updated information on laparoscopic colorectal procedures, including hand-assisted laparoscopic procedures and new chapters on the physiology of pneumoperitoneum, laparoscopic anatomy of the colon and rectum, and evidence-based discussion of outcomes. The text is complemented by over 200 line drawings created exclusively for the textbook.

Colon (Anatomy) --- Rectum --- Laparoscopic surgery. --- Endoscopic surgery. --- Minimally invasive surgery --- MIS (Minimally invasive surgery) --- Operative laparoscopy --- Operative peritoneoscopy --- Surgical laparoscopy --- Endoscopic surgery --- Laparoscopy --- Colorectum --- Cloaca (Zoology) --- Intestine, Large --- Surgery. --- Abdomen --- General Surgery. --- Abdominal Surgery. --- Colorectal Surgery. --- Abdominal surgery --- Laparotomy --- Surgery, Primitive --- Medicine --- Abdominal surgery. --- Rectum—Surgery .