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Quatrième de couverture : "La médecine factuelle (evidence-based medicine) entend concilier les exigences d’une pratique à la fois scientifique et ancrée dans l’expérience clinique. Elle s’appuie sur la recherche clinique, qui analyse rigoureusement les observations réalisées chez des malades en conditions contrôlées. La médecine factuelle est encore trop souvent présentée et discutée en référence à la formulation initiale des années 1990-1995. L’ouvrage analyse les problèmes épistémologiques et pratiques de cette première formulation, la façon dont la médecine factuelle a évolué pour y répondre et son résultat dans cette démarche. La médecine factuelle reconnaît désormais la valeur possible d’études méthodologiquement imparfaites. Elle réhabilite aussi le jugement clinique pour décider au cas par cas d’appliquer les résultats de la recherche, selon le contexte de soins et le point de vue du patient."

Clinical Trials as Topic --- Clinical Decision-Making --- ethics --- Evidence-based medicine. --- Clinical medicine. --- Clinical Medicine. --- Evidence-Based Medicine. --- Clinical Trials as Topic - ethics

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When is clinical research in developing countries exploitation? Exploitation is a concept in ordinary moral thought that has not often been analyzed outside the Marxist tradition. Yet it is commonly used to describe interactions that seem morally suspect in some way. A case in point is clinical research sponsored by developed countries and carried out in developing countries, with participants who are poor and sick, and lack education. Such individuals seem vulnerable to abuse. But does this, by itself, make such research exploitative? Exploitation and Developing Countries is an attempt by philosophers and bioethicists to reflect on the meaning of exploitation, to ask whether and when clinical research in developing countries counts as exploitative, and to consider what can be done to minimize the possibility of exploitation in such circumstances. These reflections should interest clinical researchers, since locating the line between appropriate and inappropriate use of subjects--the line between exploitation and fair use--is the central question at the heart of research ethics. Reflection on this rich and important moral concept should also interest normative moral philosophers of a non-Marxist bent. In addition to the editors, the contributors are Richard J. Arneson, Alisa L. Carse, Margaret Olivia Little, Thomas Pogge, Andrew W. Siegel, and Alan Wertheimer.

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