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This book provides a systematic and updated scientific perspective on the physiology of circadian rhythms, the molecular mechanisms of circadian entrainment, the pharmacological features derived from these signaling pathways, and their clinical outcomes. It offers a comprehensive perspective on the chronobiological impact on normal developmental processes, disruptive events that modulate the occurrence of diverse imbalances that sometimes imply disease, and the increasing importance of circadian rhythms in drug delivery.
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This book provides a systematic and updated scientific perspective on the physiology of circadian rhythms, the molecular mechanisms of circadian entrainment, the pharmacological features derived from these signaling pathways, and their clinical outcomes. It offers a comprehensive perspective on the chronobiological impact on normal developmental processes, disruptive events that modulate the occurrence of diverse imbalances that sometimes imply disease, and the increasing importance of circadian rhythms in drug delivery.
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Popular science at its most exciting: the breaking new world of chronobiology - understanding the rhythm of life in humans and all plants and animals. The entire natural world is full of rhythms. The early bird catches the worm -and migrates to an internal calendar. Dormice hibernate away the winter. Plants open and close their flowers at the same hour each day. Bees search out nectar-rich flowers day after day. There are cicadas that can breed for only two weeks every 17 years. And in humans: why are people who work anti-social shifts more illness prone and die younger? What is jet-lag and c
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This book provides a systematic and updated scientific perspective on the physiology of circadian rhythms, the molecular mechanisms of circadian entrainment, the pharmacological features derived from these signaling pathways, and their clinical outcomes. It offers a comprehensive perspective on the chronobiological impact on normal developmental processes, disruptive events that modulate the occurrence of diverse imbalances that sometimes imply disease, and the increasing importance of circadian rhythms in drug delivery.
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Circadian rhythms. --- Biological rhythms. --- Circadian rhythms
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Life on earth has evolved under a consistent cycle of light and darkness caused by the earth's rotation around its axis. This has led to a 24-hour circadian system in most organisms, ranging all the way from fungi to humans. With the advent of electric light in the 19th century, cycles of light and darkness have drastically changed. Shift workers and others exposed to high levels of light at night are at increased risk of health problems, including metabolic syndrome, depression, sleep disorders, dementia, heart disease, and cancer. This book will describe how the circadian system regulates physiology and behavior and consider the important health repercussions of chronic disruption of the circadian system in our increasingly lit world. The research summarized here will interest students in psychology, biology, neuroscience, immunology, medicine, and ecology.
Circadian rhythms. --- Circadian rhythms --- Health aspects.
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While the first edition of the critically acclaimed and highly popular Circadian Physiologyoffered a concise but rigorous review of basic and applied research on circadian rhythms, this newest edition provides educators with the primary textbook they need to support a course on this cutting-edge topic. Maintaining the same accessible multidisciplinary approach of the original, this volume provides a thorough grounding in a broad range of topics, while offering instructors many unique advantages. This impressive handbook provides the foundation, along with the supplementary material, and all the implementation details necessary to run a cutting-edge class on an exceptionally timely and intriguing topic. This edition of Circadian Physiologynot only updates the material covered in the original, but it also expands its length and scope, presenting many new findings, such as the discovery of new retinal photoreceptors, the identification of several non-hypothalamic circadian pacemakers, and the elucidation of genomic and proteomic mechanisms of biological timing. Three times the length of the original, this volume includes approximately 730 figures and 5,000 bibliographic references, making it a true handbook of circadian physiology.
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