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This is an account of the race to find the complete genetic code which defines every human and determines the way we're put together. The book demonstrates how this task has occupied researchers, from Mendel in the 19th century, through to Watson and Crick's discovery of DNA and after. It also takes a careful look at the ethical quandaries that mankind will be faced with once the research is complete.
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Chromosome Mapping --- methods --- Gene mapping. --- methods.
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Crystallins --- Chromosome Mapping --- Genes --- Polymorphism, Genetic --- genetics
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Chromosome Mapping --- Rats --- Genetic Markers --- Mice --- genetics
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Aneuploidy --- Chromosome mapping --- Down syndrome --- Phenotype
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Methodologies used to analyse the genomes of prokaryotes and eukaryotes are advancing very rapidly as it has been realized that there is a resolution gap between what can be viewed under the microscope and what molecular techniques can resolve. This book presents current, successful strategies for construction of physical maps to identify and analyse the arrangement and function of genes. These techniques, which are applicable to a range of organisms, are being used to move from linked markers to candidate genes in several human monogenic disorders. They are presented in a way that should enable any research or diagnostic laboratory to apply them to their particular systems. Also included are descriptions of new probes and approaches for the localization of human disorders whose analysis has so far eluded the molecular geneticist.
Chromosome mapping --- Chromosome Mapping --- Chromosomes --- Technique --- cartes --- Gene mapping --- -Chromosome mapping --- Genetic mapping --- Genome mapping --- Linkage mapping (Genetics) --- Mapping, Gene --- Genetics --- Chromosome Mapping. --- Basic Sciences. Bioinformatics --- Technique. --- Genome informatics --- -Technique --- Genome informatics.
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