Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

For this Special Issue book, ten papers focusing on novel bioactive molecules from different marine microorganisms, including fungi, cyanobacteria, actinobacteria and diatoms, were selected. The isolated biomolecules represent different structures and showed anticancer, antiviral, antifungal, antibacterial, anti-inflammatory and enzyme-inhibiting activities. One of the papers is a review article on microviridins, a class of bioactive cyanobacterial peptides.

marine-derived fungus --- Aspergillus terreus --- thiodiketopiperazines --- dihydroisocoumarins --- Epicoccum nigrum --- deep-sea-derived fungus --- diketopiperazine enantiomers --- cytotocxic activity --- diatoms --- marine biotechnology --- anti-inflammatory --- drug discovery --- Cylindrotheca closterium --- mangrove Streptomyces --- genetic dereplication --- anti-microbial --- antiproliferative --- endophyte fungus --- Aspergillus versicolor --- diketopiperazines --- ECD calculation --- enantiomers --- bianthraquinones --- meroterpenoids --- anti-inflammatory activity --- Stemphylium sp. --- cyanobacteria --- nostocyclopeptides --- Nostoc --- ncp gene cluster --- nonribosomal peptide synthetase --- aeruginosamides --- Limnoraphis --- cytotoxicity --- oligopeptide --- microviridin --- biotechnology --- ecology --- Penicillium citrinum --- chromone derivatives --- anti-cancer activity

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

The importance of bioactive natural compounds in pharmacology and other biotechnological fields has stimulated the scientific community to explore new environmental contexts and their associated microbial diversity. As the largest frontier in biological discovery, the sea represents a significant source of organisms producing novel secondary metabolites with interesting bioactivities. Of the available biological material, fungi have received increasing consideration, both due to their pervasive occurrence in varying habitats as well as their aptitude to develop symbiotic associations with higher organisms in numerous contexts. In many cases, fungal strains have been reported as the real producers of drugs originally extracted from marine plants and animals. Due to the constantly increasing number of marine-derived fungi yielding valuable bioactive products, it is now appropriate to present these findings to a recipient audience in a more organized form. This Special Issue of Marine Drugs, entitled “Bioactive Compounds from Marine-Derived Aspergillus, Penicillium, Talaromyces, and Trichoderma Species"" is specifically focused on a few genera of ascomycetous fungi which are widespread regarding marine contexts and are particularly inclined to establishing symbiotic relationships. For this project, we welcome submissions of full research papers, short notes, and review articles reporting the discovery and characterization of products showing antibiotic, antitumor, antiviral, insecticidal, antimalarial, antifouling, antioxidant, plant growth-promoting and/or resistance-inducing, as well as other less-exploited activities.

antibacterial activity --- n/a --- Talaromyces purpurogenus --- lapatinib --- antibacterial --- hydroxypyrrolidine --- bis-indolyl benzenoids --- penitrem A --- cytotoxicities --- sesquiterpenoid --- secondary metabolites --- drug discovery --- sponge-associated fungus --- candidusin --- Penicillium sp. TJ403-1 --- coumarin --- gefitinib --- bioactive products --- Aspergillaceae --- indole-diterpenoids --- mangroves --- diterpenoid --- Penicillium raistrickii --- ECD calculations --- Talaromyces --- marine-derived fungi --- BK (Maxi-K) channel --- polyketides --- EGFR --- chromone --- aspetritone --- Aspergillus --- breviane spiroditerpenoid --- endophytic fungi --- cytotoxic --- cytotoxicity --- breast cancer --- mangrove endophytic fungus --- IDH1 inhibitory activity --- NMR data calculations --- antifungal activity --- Aspergillus candidus --- diastereomers --- TNF-? --- sterone --- Aspergillus clavatus --- HER2 --- thermo-change strategy

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

With the development of analytical instruments, the academic system has become more complicated, producing new journals one after another. Therefore, it became much important to clarify what is original of “Medicines”. As the name Medicines indicates, it includes science and practice of caring for a patient and managing the diagnosis, prognosis, prevention, treatment or palliation of their injury or disease. Therefore, Medicines differs from other journals with similar title in that it covers a wide range of fields, from traditional medicine to rapidly developing molecular-targeted drugs, focusing on their pharmacological effects, structure–activity relationships, metabolic pathways, gene expression, using cultured cells, animals, and clinical trials. Most parts of this Special Issue were written by our editorial board members, who described the research topics and how they are engaged in their field of research. All of these articles are their life-long story. We collected a total number of 22 original works by basic researchers and clinical doctors. We hope that readers can get a chance to know the current status of diverse fields of medicines, and what your most important research themes are after reading these articles.

Medicine --- Hedychium --- traditional medicine --- coronarin D --- villosin --- anti-acetylcholinesterase --- antidiabetic --- anti-inflammatory --- antimicrobial --- antioxidant --- antitumor --- Genista tridentata --- Pterospartum tridentatum --- isoflavones --- flavonols --- genistein --- biochanin A --- rutin --- daidzein --- inflammatory bowel disease --- Crohn’s disease --- ulcerative colitis --- extra-intestinal manifestations --- orofacial granulomatosis --- tag-like lesions --- cobblestoning --- mucogingivitis --- lip swelling --- aphthous stomatitis --- Angelicae Sinensis Radix --- Danggui --- granules --- herb --- multivariate analysis --- ultra-performance liquid chromatography --- Tai Chi --- qigong --- immune system --- immunity --- inflammation --- telemedicine --- remote monitoring --- GER-e-TEC --- elderly patient --- artificial intelligence --- geriatric syndromes --- detection of the precursory signs of decompensation of geriatric syndromes --- renal cell cancer --- genomic landscape --- targeted therapy --- tumor evolution --- tumor heterogeneity --- allergic rhinitis --- quercetin --- human CD4+ T cells --- Th1/Th2 cytokine balance --- modulation --- in vitro --- intravascular catheter --- CRBSI --- biofilm --- CVC --- antifouling --- chromone --- tumor specificity --- QSAR analysis --- apoptosis --- cell cycle analysis --- contrast-enhanced ultrasound --- hepatocellular carcinoma --- LI-RADS --- chronic liver disease --- granuloma annulare --- granulomatous disorders of the skin --- inflammatory skin conditions --- medical dermatology --- biliary tract cancer --- cholangiocarcinoma --- PARP --- BRCA --- olaparib --- rucaparib --- liver cancer --- pancreatic adenocarcinoma --- pancreatic cancer --- sarcoidosis --- superior vena cava syndrome --- venous thrombosis --- RUCAM --- Roussel Uclaf Causality Assessment Method --- diagnostic algorithm --- iDILI --- iDrug induced liver injury --- DILI --- HILI --- herb induced liver injury --- Stachys L. --- traditional uses --- pharmacological activities --- phytochemicals --- bioactive compounds --- Kampo formulae --- alkaline extract of Sasa sp. --- pine cone extract --- povidone-iodine --- HSV --- HIV --- loss of infectivity --- solubilization method --- diaphragmatic breathing --- abdominal breathing --- breathing exercise --- systematic review --- randomized controlled trial --- respiratory function --- auricular acupuncture --- preoperative anxiety --- protocol --- randomized controlled trials --- meta-analysis --- boiogito --- knee osteoarthritis --- rat --- Yokukansan --- fentanyl --- transient receptor potential ankyrin 1 (TRPA1) channel --- phosphorylated extracellular signal-regulated kinase (pERK) --- whole-cell patch-clamp recording --- herbal medicine --- calcium metabolism --- bone metabolism --- protease --- osteoclast --- macrophage --- RANKL --- LPS --- TLR4 --- TREM2

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

With the development of analytical instruments, the academic system has become more complicated, producing new journals one after another. Therefore, it became much important to clarify what is original of “Medicines”. As the name Medicines indicates, it includes science and practice of caring for a patient and managing the diagnosis, prognosis, prevention, treatment or palliation of their injury or disease. Therefore, Medicines differs from other journals with similar title in that it covers a wide range of fields, from traditional medicine to rapidly developing molecular-targeted drugs, focusing on their pharmacological effects, structure–activity relationships, metabolic pathways, gene expression, using cultured cells, animals, and clinical trials. Most parts of this Special Issue were written by our editorial board members, who described the research topics and how they are engaged in their field of research. All of these articles are their life-long story. We collected a total number of 22 original works by basic researchers and clinical doctors. We hope that readers can get a chance to know the current status of diverse fields of medicines, and what your most important research themes are after reading these articles.

Medicine --- Hedychium --- traditional medicine --- coronarin D --- villosin --- anti-acetylcholinesterase --- antidiabetic --- anti-inflammatory --- antimicrobial --- antioxidant --- antitumor --- Genista tridentata --- Pterospartum tridentatum --- isoflavones --- flavonols --- genistein --- biochanin A --- rutin --- daidzein --- inflammatory bowel disease --- Crohn’s disease --- ulcerative colitis --- extra-intestinal manifestations --- orofacial granulomatosis --- tag-like lesions --- cobblestoning --- mucogingivitis --- lip swelling --- aphthous stomatitis --- Angelicae Sinensis Radix --- Danggui --- granules --- herb --- multivariate analysis --- ultra-performance liquid chromatography --- Tai Chi --- qigong --- immune system --- immunity --- inflammation --- telemedicine --- remote monitoring --- GER-e-TEC --- elderly patient --- artificial intelligence --- geriatric syndromes --- detection of the precursory signs of decompensation of geriatric syndromes --- renal cell cancer --- genomic landscape --- targeted therapy --- tumor evolution --- tumor heterogeneity --- allergic rhinitis --- quercetin --- human CD4+ T cells --- Th1/Th2 cytokine balance --- modulation --- in vitro --- intravascular catheter --- CRBSI --- biofilm --- CVC --- antifouling --- chromone --- tumor specificity --- QSAR analysis --- apoptosis --- cell cycle analysis --- contrast-enhanced ultrasound --- hepatocellular carcinoma --- LI-RADS --- chronic liver disease --- granuloma annulare --- granulomatous disorders of the skin --- inflammatory skin conditions --- medical dermatology --- biliary tract cancer --- cholangiocarcinoma --- PARP --- BRCA --- olaparib --- rucaparib --- liver cancer --- pancreatic adenocarcinoma --- pancreatic cancer --- sarcoidosis --- superior vena cava syndrome --- venous thrombosis --- RUCAM --- Roussel Uclaf Causality Assessment Method --- diagnostic algorithm --- iDILI --- iDrug induced liver injury --- DILI --- HILI --- herb induced liver injury --- Stachys L. --- traditional uses --- pharmacological activities --- phytochemicals --- bioactive compounds --- Kampo formulae --- alkaline extract of Sasa sp. --- pine cone extract --- povidone-iodine --- HSV --- HIV --- loss of infectivity --- solubilization method --- diaphragmatic breathing --- abdominal breathing --- breathing exercise --- systematic review --- randomized controlled trial --- respiratory function --- auricular acupuncture --- preoperative anxiety --- protocol --- randomized controlled trials --- meta-analysis --- boiogito --- knee osteoarthritis --- rat --- Yokukansan --- fentanyl --- transient receptor potential ankyrin 1 (TRPA1) channel --- phosphorylated extracellular signal-regulated kinase (pERK) --- whole-cell patch-clamp recording --- herbal medicine --- calcium metabolism --- bone metabolism --- protease --- osteoclast --- macrophage --- RANKL --- LPS --- TLR4 --- TREM2