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Combinatorial Chemistry encompasses both the design of compounds for specific pharmacological use and the screening of molecules in high throughput automated tests to find active agents with specific functions.*Analytical techniques*Direct sorting split and pool combinatorial synthesis*Linkers and their applications*Microwave assisted synthesis*Oligosaccharide chemistry*Peptide Synthesis and Screening*Polymer assisted approaches*Small molecule and heterocycle synthesis
Enzymology --- Chimie combinatoire --- Chimie pharmaceutique --- VIRUS, BACTERIAL --- MOLECULAR LIBRARIES --- NUCLEIC ACIDS --- AMINO ACIDS --- REACTIONS
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Chemistry, Pharmaceutical. --- Pharmaceutical Preparations --- Drug Design. --- Chemistry, Pharmaceutical --- Quimica farmaceutica --- Combinatorial chemistry. --- Chimie combinatoire --- chemical synthesis. --- 547.057 --- Organic synthesis --- Combinatorial chemistry --- Combinatorial organic synthesis --- Combinatorial synthesis (Organic chemistry) --- High-throughput organic synthesis --- High-throughput synthesis (Organic chemistry) --- Multiple parallel synthesis (Organic chemistry) --- Organic compounds --- Pharmaceutical chemistry --- Biochips --- Synthesis
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Chemistry, Pharmaceutical --- Drug Design --- Gene Library --- Pharmaceutical Preparations --- Combinatorial chemistry --- Pharmaceutical chemistry --- Chimie combinatoire --- Chimie pharmaceutique --- chemical synthesis --- Periodicals. --- Periodicals --- Périodiques --- Synthese (chemie) --- JEX7 --- Chemistry. --- Chemistry --- Engineering --- Health Sciences --- Life Sciences --- Material Science and Metallurgy --- General and Others --- Biotechnology --- Chemical Engineering --- Pharmacy and Pharmacology --- Composites
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Combinatorial chemistry --- Chemistry, Pharmaceutical --- Drug Design --- Gene Library --- Pharmaceutical Preparations --- Chimie combinatoire --- Synthese (chemie) --- chemical synthesis --- JEX7 --- Chemistry, Pharmaceutical. --- Drug Design. --- Gene Library. --- chemical synthesis. --- Chemistry - Combinations thereof --- Chemistry - Combinations thereof. --- Chemistry --- Engineering --- Health Sciences --- Life Sciences --- Material Science and Metallurgy --- General and Others --- Biotechnology --- Chemical Engineering --- Pharmacy and Pharmacology --- Composites
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57.081.2 --- 57 --- 542 <05> --- 57.081.2 Automation of biological experiments --- Automation of biological experiments --- 542 <05> Practical laboratory chemistry. Preparative and experimental chemistry--Tijdschriften --- Practical laboratory chemistry. Preparative and experimental chemistry--Tijdschriften --- Biological sciences in general --- Periodicals --- Chemical laboratories --- Miniature electronic equipment --- Combinatorial chemistry --- Biotechnology --- Nanotechnology --- Nanotechnology. --- Biotechnology. --- Microchemistry. --- Miniaturization. --- Équipement électronique miniaturisé --- Chimie combinatoire --- Biotechnologie --- Combinatorial chemistry. --- Miniature electronic equipment. --- Microélectronique. --- Appareil électronique. --- Biotechnologie. --- Chimie combinatoire. --- Electronic equipment, Miniature --- Microminiaturization (Electronics) --- Miniaturization (Electronics) --- Subminiature electronic equipment --- Subminiaturization (Electronics) --- Electronic apparatus and appliances --- Microelectronics --- Combinatorial organic synthesis --- Combinatorial synthesis (Organic chemistry) --- High-throughput organic synthesis --- High-throughput synthesis (Organic chemistry) --- Multiple parallel synthesis (Organic chemistry) --- Organic compounds --- Pharmaceutical chemistry --- Biochips --- Chemical engineering --- Genetic engineering --- Miniaturisation --- Miniaturisations --- Miniaturizations --- Microchemistry --- Miniaturization --- Biosensing Techniques --- Lab-On-A-Chip Devices --- Biotechnologies --- Chemistry laboratories --- Laboratories --- Nanotechnologies --- Nanotubes --- Microchip Analytical Procedures --- Nanostructures --- Electronic equipment --- Synthesis --- Molecular technology --- Nanoscale technology --- High technology --- Electronic equipment. --- Chemistry --- Engineering --- Life Sciences --- General and Others --- Electrical Engineering --- Computational Biosciences
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The essence of combinatorial chemistry or techniques involving "molecular diversity" is to generate enormous populations of molecules and to exploit appropriate screening techniques to isolate active components contained in these libraries. This idea has been the focus of research both in academia and in the pharmaceutical or biotechnology industry. Its developments go hand in hand with an exploding number of potential drug targets emerging from genomics and proteomics research. When the editors of Current Topics in Microbiology and Immunology encouraged us to assemble the present volume on Combinatorial Chemistry in Biology, we immediately felt that this might prove quite beneficial for the audience of this series. The field of combinatorial chemistry extends over a broad range of disciplines, from synthetic organic chemistry to biochemistry, from material sciences to cell biology. Each of these fields may have its own view on this topic, something which is reflected in a growing number of monographs and "special editions" of jour nals devoted to this issue or aspects thereof. The title of the present volume of Springer-Verlag's series suggests that it also has its own special focus. And, generally speaking, this is not wrong: we would even claim the special focus of this volume is on the immunologically relevant aspects of combinatorial chemistry.
Biologie [Moleculaire ] --- Biologie moléculaire --- Biology [Molecular ] --- Chemie [Combinatorische ] --- Chemistry [Combinatorial ] --- Chimie combinatoire --- Combinatorial chemistry --- Combinatorische chemie --- Moleculaire biologie --- Molecular biochemistry --- Molecular biology --- Molecular biophysics --- Molecular Conformation. --- Biochemistry --- Immunity --- Biochemistry. --- Immunity. --- Immunology. --- Cell biology. --- Biotechnology. --- Cell Biology. --- Chemical engineering --- Genetic engineering --- Cell biology --- Cellular biology --- Biology --- Cells --- Immunobiology --- Life sciences --- Serology --- Combinatorial chemistry. --- Combinatorial organic synthesis --- Combinatorial synthesis (Organic chemistry) --- High-throughput organic synthesis --- High-throughput synthesis (Organic chemistry) --- Multiple parallel synthesis (Organic chemistry) --- Organic compounds --- Pharmaceutical chemistry --- Biochips --- Synthesis
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Catalysts are central in modern industrial chemistry and there is an urgent need to develop new catalysts. Such a rapid pace of development brings with it a new set of challenges at all levels of research, from synthesis and characterization to testing and modelling. This book reviews the current status of combinatorial catalysis, scientific catalyst design techniques, methods for preparing inorganic combinatorial libraries, experimental design methods, data processing, system modelling an simulation, and catalyst testing. The individual contributions reveal the development of high throughput catalyst design and test methods and identify the main challenges in the field, including new catalyst preparation techniques, rapid performance evaluation, and new microreactor configurations. Readership: All those working in catalytic process analysis and development. The extensive review of catalysis principles is especially relevant for postgraduate students seeking to pursue studies in catalysis.
Catalysis --- Catalysts --- Combinatorial chemistry --- Design --- Congresses --- Chemistry, Physical organic. --- Chemical engineering. --- Chemistry. --- Physical Chemistry. --- Industrial Chemistry/Chemical Engineering. --- Computer Applications in Chemistry. --- Physical sciences --- Chemistry, Industrial --- Engineering, Chemical --- Industrial chemistry --- Engineering --- Chemistry, Technical --- Metallurgy --- Chemistry, Physical organic --- Chemistry, Organic --- Chemistry, Physical and theoretical --- Physical chemistry. --- Chemoinformatics. --- Chemical informatics --- Chemiinformatics --- Chemoinformatics --- Chemistry informatics --- Chemistry --- Information science --- Computational chemistry --- Chemistry, Theoretical --- Physical chemistry --- Theoretical chemistry --- Data processing --- Catalyseurs --- Catalyse --- Chimie combinatoire --- Conception
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High throughput experimentation has met great success in drug design but it has, so far, been scarcely used in the field ofcatalysis. We present in this book the outcome of a NATO ASI meeting that was held in Vilamoura, Portugal, between July 15 and 28, 2001, with the objective of delineating and consolidating the principles and methods underpinning accelerated catalyst design, evaluation, and development. There is a need to make the underlying principles of this new methodology more widely understood and to make it available in a coherent and integrated format. The latter objective is particularly important to the young scientists who will constitute the new catalysis researchers generation. Indeed, this field which is at the frontier offundamental science and may be a renaissance for catalysis, is one which is much more complex than classical catalysis itself. It implies a close collaboration between scientists from many disciplines (chemistry, physics, chemical and mechanical engineering, automation, robotics, and scientific computing in general). In addition, this emerging area of science is also of paramount industrial importance, as progress in this area would collapse the time necessary to discover new catalysts or improve existing ones.
Catalysis --- Catalysts --- Combinatorial chemistry --- Congresses. --- Design --- Catalyse --- Chimie combinatoire --- Congresses --- Congrès --- Physical chemistry. --- Chemical engineering. --- Chemoinformatics. --- Physics. --- Physical Chemistry. --- Industrial Chemistry/Chemical Engineering. --- Computer Applications in Chemistry. --- Physics, general. --- Natural philosophy --- Philosophy, Natural --- Physical sciences --- Dynamics --- Chemical informatics --- Chemiinformatics --- Chemoinformatics --- Chemistry informatics --- Chemistry --- Information science --- Computational chemistry --- Chemistry, Industrial --- Engineering, Chemical --- Industrial chemistry --- Engineering --- Chemistry, Technical --- Metallurgy --- Chemistry, Theoretical --- Physical chemistry --- Theoretical chemistry --- Data processing --- Catalysis - Congresses. --- Catalysts - Design - Congresses. --- Combinatorial chemistry - Congresses.
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A WWW only publication which contains articles on combinatorial chemistry accepted for publication in: Tetrahedron, Tetrahedron Letters, Tetrahedron:Asymmetry, Bioorganic & Medicinal Chemistry, Bioorganic & Medicinal Chemistry Letters, CarbohydrateResearch, and other relevant Elsevier Science journals. It also features specially commissioned topical reports, as well as abstracts of articles from other publications. Articles are designated with page number and are published continuously in annual volumes.
chemie --- Descriptive organic chemistry --- Combinatorial chemistry --- Chimie combinatoire --- Periodicals. --- Périodiques --- Combinatorial chemistry. --- Biotechnologie. --- Zeitschrift. --- Online-Publikation. --- Kombinatorische Synthese. --- Combinatorial organic synthesis --- Combinatorial synthesis (Organic chemistry) --- High-throughput organic synthesis --- High-throughput synthesis (Organic chemistry) --- Multiple parallel synthesis (Organic chemistry) --- Biotechnologie --- Kombinatorische Synthese --- Online-Ressource --- Zeitschrift --- Organic compounds --- Pharmaceutical chemistry --- Biochips --- Periodikum --- Zeitschriften --- Presse --- Fortlaufendes Sammelwerk --- Netzpublikation --- Online-Publikation --- Computerdatei im Fernzugriff --- Online-Dokument --- On-line-Dokument --- On-line-Publikation --- Elektronische Publikation --- Kombinatorische Chemie --- Kombinatorische Biologie --- Biokombinatorische Synthese --- Organische Synthese --- Molekülbibliothek --- Technische Biochemie --- Technische Biologie --- Biotechnik --- Biotech --- Industrielle Mikrobiologie --- Synthesis --- Molekülbibliothek --- Online-Ressource.
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