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Book
Skin sensitization in chemical risk assessment
Authors: --- --- --- --- --- et al.
ISBN: 9241563605 9786611937799 1281937797 9240683445 Year: 2008 Publisher: Geneva, Switzerland : World Health Organization,

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Abstract

This Harmonization Project Document presents the conclusions of an IPCS Workshop on Skin Sensitization in Chemical Risk Assessment. The workshop focused on the question of methods for dose-response assessment, to evaluate the relative ability of a chemical to induce sensitization in the skin, and hence inform risk assessment for humans. In addition this publication includes a series of short articles on this topic by leading experts in the field. The conclusions of the workshop cover such aspects as the nature and utility for risk assessment of the data produced by non-animal test methods (suc

Keywords

Chemicals -- Physiological effect. --- Chemicals -- Risk assessment. --- Health risk assessment. --- Skin tests. --- Toxicology. --- Chemicals --- Hazardous substances --- Skin tests --- Toxicology --- Health risk assessment --- Skin Tests --- Hazardous Substances --- Risk Assessment --- Dermatitis, Contact --- Methods --- Dermatitis --- Immunologic Tests --- Environmental Pollutants --- Skin Diseases, Eczematous --- Investigative Techniques --- Risk --- Diagnostic Techniques and Procedures --- Risk Management --- Epidemiologic Measurements --- Immunologic Techniques --- Probability --- Skin Diseases --- Laboratory Techniques and Procedures --- Organization and Administration --- Public Health --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Diagnosis --- Toxic Actions --- Environment and Public Health --- Statistics as Topic --- Skin and Connective Tissue Diseases --- Chemical Actions and Uses --- Health Services Administration --- Health Care --- Health Care Evaluation Mechanisms --- Diseases --- Chemicals and Drugs --- Epidemiologic Methods --- Quality of Health Care --- Health Care Quality, Access, and Evaluation --- Environmental Engineering --- Civil & Environmental Engineering --- Engineering & Applied Sciences --- Physiological effect --- Risk assessment --- Physiological effect. --- Risk assessment. --- Electronic texts --- Biological and medical sciences. --- Assessment, Health risk --- Health hazard appraisal --- Health hazard assessment --- Health risk appraisal --- HRA (Public health) --- Human risk assessment --- Cutaneous tests --- Chemical compounds --- Compounds, Chemical --- Medicine, Preventive --- Public health --- Environmental health --- Medicine --- Pharmacology --- Poisoning --- Poisons --- Provocation tests (Medicine) --- Chemistry


Book
Exposure and risk assessment of chemical pollution : contemporary methodology
Authors: ---
ISBN: 9048123348 9786612069444 1282069446 9048123356 904812333X Year: 2009 Publisher: Dordrecht, Netherlands : Springer,

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Abstract

The book contains the contributions at the NATO Study Institute on Exposure and Risk Assessment of Chemical Pollution – Contemporary Methodology, which took place in Sofia – Borovetz, Bulgaria, July 1–10, 2008. Rapid advances in mathematics, computer science and molecular biology and chemistry have lead to the development in of a new branch of toxicology called Computational Toxicology. This emerging field is addressing the estimation and prediction of exposure risk and effects of chemicals based on experimental data, measured concentration and biological mechanisms and computational models of biological systems. Mathematical models are also being used to predict the fate and transport of substances in the environment. Because this area is still in its infancy, there has been limited application from governmental agencies to regulating controllable processes, such as registration of new chemicals, determination of estimated exposure and risk based limits and maximum acceptable concentrations in different compartments of the environment – ambient air, waters, soil and food products. However, this is soon to change as the ability to collect, analyze and interpret the required information is becoming increasingly more efficient and cost effective. Full implementation of the new processes have to involve education on both part of the experimentalists who are generating the data and the models, and the risk assessors who will use them to better protect human health and the environment.

Keywords

Chemical industry -- Risk assessment -- Congresses. --- Chemical industry -- Safety measures -- Congresses. --- Chemicals -- Risk assessment -- Congresses. --- Environmental risk assessment -- Congresses. --- Pollution -- Environmental aspects -- Congresses. --- Agriculture - General --- Environmental Engineering --- Ecology --- Civil & Environmental Engineering --- Earth & Environmental Sciences --- Agriculture --- Engineering & Applied Sciences --- Pollution. --- Hazardous wastes. --- Hazardous waste disposal --- Poisonous wastes --- Toxic waste disposal --- Toxic waste release --- Toxic wastes --- Waste disposal --- Wastes, Hazardous --- Chemical pollution --- Chemicals --- Contamination of environment --- Environmental pollution --- Pollution --- Environmental aspects --- Environment. --- Analytical chemistry. --- Noise control. --- Soil science. --- Soil conservation. --- Environmental pollution. --- Environmental Monitoring/Analysis. --- Noise Control. --- Pollution, general. --- Soil Science & Conservation. --- Analytical Chemistry. --- Terrestrial Pollution. --- Contamination (Technology) --- Asbestos abatement --- Bioremediation --- Environmental engineering --- Environmental quality --- Factory and trade waste --- Hazardous waste site remediation --- Hazardous wastes --- In situ remediation --- Lead abatement --- Pollutants --- Refuse and refuse disposal --- Hazardous substances --- Analytical biochemistry. --- Monitoring/Environmental Analysis. --- Analytic biochemistry --- Biochemistry --- Chemistry, Analytic --- Conservation of soil --- Erosion control, Soil --- Soil erosion --- Soil erosion control --- Soils --- Agricultural conservation --- Soil management --- Noise prevention --- Acoustical engineering --- Noise --- Control --- Prevention --- Conservation --- Bioanalytic chemistry --- Bioanalytical chemistry --- Analytical chemistry --- Environmental monitoring. --- Analysis, Chemical --- Analytic chemistry --- Chemical analysis --- Chemistry --- Pedology (Soil science) --- Earth sciences --- Biomonitoring (Ecology) --- Ecological monitoring --- Monitoring, Environmental --- Applied ecology --- Measurement --- Monitoring --- Environmental sciences. --- Environmental science --- Science

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