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The food processing industries produce millions of tons of losses and waste during processing, which are becoming a grave economic, environmental, and nutritional problem. Fruit, vegetable, and food industrial solid waste include leaves, peels, pomace, skins, rinds pulp, stems, seeds, twigs, and spoiled fruits and vegetables, among other waste released in food production, which can be formed during cleaning, processing, cooking, and/or packaging. These wastes are characterized by being an important source of bioactive compounds, such as phenolic compounds, dietary fibers, polysaccharides, vitamins, carotenoids, pigments, and oils, among others. These bioactive compounds are closely associated with beneficial effects on human health. These by-products can be exploited in different industries: in food industries for the development of functional ingredients and/or new foods or natural additives; in pharmaceutical industries for medicinal, healthcare, or cosmetic products; in agricultural industries as fertilizers or animal feed; and in chemical industries, among others. The reutilization of these by-products will ensure the sustainable development of food industries and reduce their environmental impact, which will contribute to the fight against environmental problems, leading to potential mitigation of climatic change. Therefore, the determination of bioactive compound composition in agricultural and food waste and the production of extracts containing these compounds is the first step towards its reutilization.

Research. --- Biology. --- Food --- Natural red pigment --- Monascus purpureus --- Brewer’s spent grain --- Submerged fermentation --- Plackett-Burman design --- Chemical characterization --- X-ray photoelectron spectroscopy (XPS) --- Fourier-transform infrared spectroscopy (FTIR) --- Cucumis melo --- polyphenols --- flavonoids --- antioxidants --- by-products --- waste valorization --- LC-MS/MS --- fatty acids --- antioxidant activity --- reutilization of food waste --- salted egg white --- ovalbumin --- extraction --- aqueous two-phase flotation --- cork --- volatile compounds --- aroma --- waste --- bioactive compounds --- food waste --- functional foods --- characterization and extraction --- phytochemicals --- climatic change --- phenolic compounds --- Social aspects.

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The large production and widespread daily consumption of plastic materials which began in the last century, together with the often inadequate collection and recycling systems, have made plastics and, consequently, microplastics (MPs) ubiquitous pollutants. Microplastic pollution as a global concern is confirmed by the research papers collected in this Special Issue; these papers come from 28 Universities and research institutions and are spread across ten countries on three continents. This Special Issue collected and published 11 novel contributions focusing on microplastics in aquatic environments, their occurrence and distribution, and the effects they might have on the environment and biota. As Guest Editors of this Special Issue, we were pleased to receive several papers concerning the interaction between microplastics and biota; despite a large number of peer-reviewed papers published on this research topic, there are still several gaps that need to be filled and there is concrete evidence suggesting that microplastic pollution may constitute a serious hazard to aquatic biota. The results of the contributions collected herein have helped to fill some knowledge gaps about the occurrence, distribution, and effects of microplastics on aquatic ecosystems. The outcomes clearly indicate that microplastic pollution is a serious environmental issue; the scientific community should increase its knowledge and understanding of how it could affect the environment, biota, and humans, and how it could be reduced and prevented.

Medicine --- Medical toxicology --- source --- fate --- bacterial degradation --- marine environment --- microplastics --- microplastic pollutant --- polystyrene --- biodegradation --- microalgae --- per- and polyfluoroalkyl substances --- Muskegon Lake --- plastics --- riverine --- coastal --- estuary --- characteristics --- pollution --- population growth rate --- polyamide --- silica beads --- fitness response --- rotifers --- Brachionus fernandoi --- Brachionus calyciflorus --- egg ratio --- polystyrene microplastics --- size-dependent uptake --- vectors --- cadmium --- benzo(a)pyrene --- mussels --- invasive macroalgae --- bivalves --- marine debris --- oxidative stress --- energy balance --- byssus production --- microplastic --- grass carp --- size --- accumulation --- re-consumption --- shape --- colour --- polymer type --- blackfly larvae --- freshwaters --- Simuliidae --- additives --- plasticizers --- fibers --- cellulose --- Mediterranean Sea --- chemical characterization --- environmental pollution --- biota contamination --- n/a

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This Special Issue of Marine Drugs gathers recent investigations on the proteomes, metabolomes, transcriptomes, and the associated microbiomes of marine jellyfish and polyps, including bioactivity studies of their compounds and more generally, on their biotechnological potential, witnessing the increasingly recognized importance of Cnidaria as a largely untapped Blue Growth resource for new drug discovery. These researches evoke the outstanding ecological importance of cnidarians in marine ecosystems worldwide, calling for a global monitoring and conservation of marine biodiversity, so that the biotechnological exploitation of marine living resources will be carried out to conserve and sustainably use the natural capital of the oceans.

Technology: general issues --- cnidarian --- sea anemone --- proteins --- toxins --- two-dimensional gel electrophoresis --- MALDI-TOF/TOF --- shotgun proteomic --- Zoanthidea --- holo-transcriptome --- cnidarian transcriptome --- marine enzyme --- marine biocatalyst --- marine biotechnology --- pharmaceutical biotechnology --- anthozoa --- microbial communities --- cnidarian holobiont --- zooxanthellae --- bleaching --- antibacterial activity --- jellyfish --- Aurelia coerulea --- mucus --- proteomics --- metabolomics --- cnidarians --- gelatinous zooplankton --- bioprospecting --- novel foods --- transcriptomics --- bio-prospecting --- computational biology --- neurotoxins --- NMR spectroscopy --- biochemical characterization --- jellyfish blooms --- Cnidaria --- Ctenophora --- biodiversity --- bioactive compounds --- blue biotechnology --- invertebrate proteins --- biological activity --- antioxidants --- collagen --- pepsin hydrolysis --- collagenase hydrolysis --- oxidative stress --- keratinocytes --- cytotoxicity --- Easter Island --- Actinobacteria --- anthraquinones --- symbionts --- marine invertebrates --- spectroscopy --- chromatography --- Pelagia noctiluca --- Mediterranean jellyfish --- chemical characterization --- aquafeed and food supplements --- sustainable fishing

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Lignans are a class of natural products found mainly in plants. They have a wide variety of structures and exhibit a range of potent biological activities. Lignans are also well-known components of a number of widely eaten foods and are frequently studied for their dietary impact. Owing to these factors, lignans have been extensively studied by scientists from a large number of disciplines. This collection of research and review articles describes topics ranging in scope from the recent isolation and structural elucidation of new lignans, strategies towards the chemical synthesis of lignans, assessment of their biological activities and potential for further therapeutic development. Research showing the impact of lignans in the food and agricultural industries is also presented.

taste-active compound --- heilaohu --- 9-norlignans --- antioxidant activity --- drug-like --- human health --- chemometrics --- lignan --- bitterness --- red-flowered Chinese magnolia vine --- antioxidant --- ruminant --- secoisolariciresinol diglucoside --- quantification --- intermolecular interactions --- cattle --- anti-inflammatory activity --- acyl-Claisen --- LOX --- seed --- food groups --- microtubules --- anti-proliferative --- acetylcholinesterase inhibitors --- flax --- arylnaphthalene lignan --- epiboly --- aryldihydronaphthalene lignan --- multiple bioactive components --- enterolignan --- total synthesis --- genetic --- synthesis --- cultivated --- cell cycle --- chronic diseases --- national databases --- oxidation --- chemical components --- molecular dynamics --- COX --- lignans --- hydroxycinnamic acid --- chemical structures --- Chinese magnolia vine --- stereoselective synthesis --- sPLA2 --- Bursera fagaroides --- in silico studies --- antibacterial activity --- semisynthesis --- dibenzyl butyrolactones --- flavonoid glycoside --- lignan glycoside --- chemical characterization --- hydroxymatairesinol --- podophyllotoxin --- Lespedeza cuneata --- Bursera --- oak ageing --- Schisandrae Chinensis Fructus --- F-actin --- cultivar --- UHPLC-MS/MS --- bioactivity --- podophyllotoxin-type lignans --- harmonized databases --- graph theory --- antioxidants --- health promotion --- simultaneous quantitation --- natural products --- dietary intake --- cell migration --- Lignan --- chemical space --- diet --- Lauraceae --- pharmacokinetic --- cytotoxicity --- tujia ethnomedicine --- flavonolignans --- flavonol --- adipocyte and osteoblast differentiation --- Burseraceae --- environment --- dietary lignans --- phytochemical analysis --- Schisandra chinensis --- animal health --- neolignans --- Schisandra rubriflora --- cancer --- norlignans --- wild

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In recent years, there has been rapid growth in the availability of innovative, non-combustible products, including oral tobacco-derived nicotine (OTDN) products, heated tobacco products (HTPs), and electronic cigarettes (also referred to as e-vapor products; EVPs). Industry, academic, and government researchers are developing and validating analytical methods to extract, separate, identify, and quantitate a variety of analytes from these innovative tobacco products using a wide range of analytical techniques. These analytes include constituents such as nicotine, degradants and impurities, flavors, non-tobacco ingredients, HPHCs, and other currently unknown constituents. In this Special Issue, we received nine contributions that covered the latest analytical methods that have been developed and applied for the chemical characterization or exposure assessment to tobacco product constituents of innovative non-combustible products. This Special Issue is representative of the importance of analytical sciences research in characterizing innovative non-combustible products for guiding product design, determining relative product performance, ensuring consistency during the manufacturing process, informing toxicological risk assessment, and enabling regulatory reporting. The current advances in the development and applications of the analytical methods reported in this Special Issue can be used to inform the harm reduction potential of innovative non-combustible products for adult smokers.

Research & information: general --- Chemistry --- Analytical chemistry --- on!® nicotine pouches --- nicotine --- dissolution --- release profile --- validation --- product assessment --- smokeless tobacco product --- nicotine degradants --- nicotine-related impurities --- alkaloids --- nicotine degradation products --- nicotine pouches --- reduced-risk products --- constituents --- method development --- method validation --- JUUL --- aerosol --- non-targeted analysis --- chemical characterization --- ENDS --- e-cigarette --- GC–MS --- LC–HRMS --- e-liquid --- 2,4-DNPH derivatization --- formaldehyde --- “hidden formaldehyde” --- formaldehyde-containing hemiacetal/acetal adducts --- HPHC --- GC-MS --- 3-hydroxybenzo[a]pyrene --- LC–MS/MS --- urine --- human biomonitoring --- derivatization --- potentially reduced-risk products --- propylene glycol --- electronic cigarette --- biomarker of exposure --- compliance marker --- oral tobacco derived nicotine (OTDN) pouches --- snus --- nicotine release --- nicotine dissolution --- nicotine extraction --- equivalence --- modern oral nicotine products --- HPHCs --- product characterizations --- n/a --- LC-HRMS --- --- LC-MS/MS