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The Cytokines of the Immune System catalogs cytokines and links them to physiology and pathology, providing a welcome and hugely timely tool for scientists in all related fields. In cataloguing cytokines, it lists their potential for therapeutic use, links them to disease treatments needing further research and development, and shows their utility for learning about the immune system. This book offers a new approach in the study of cytokines by combining detailed guidebook-style cytokine description, disease linking, and presentation of immunologic roles. Supplies new ideas for basic and clin
Cancer -- Immunotherapy. --- Cytokines -- Therapeutic use. --- T cells -- Therapeutic use. --- Cytokines --- Immunity, Cellular --- Intercellular Signaling Peptides and Proteins --- Adaptive Immunity --- Immunity --- Biological Factors --- Peptides --- Proteins --- Immune System Phenomena --- Amino Acids, Peptides, and Proteins
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The Cytokines of the Immune System catalogs cytokines and links them to physiology and pathology, providing a welcome and hugely timely tool for scientists in all related fields. In cataloguing cytokines, it lists their potential for therapeutic use, links them to disease treatments needing further research and development, and shows their utility for learning about the immune system. This book offers a new approach in the study of cytokines by combining detailed guidebook-style cytokine description, disease linking, and presentation of immunologic roles. Supplies new ideas for basic and clin
Cancer -- Immunotherapy. --- Cytokines -- Therapeutic use. --- T cells -- Therapeutic use. --- Cytokines --- Immunity, Cellular --- Intercellular Signaling Peptides and Proteins --- Adaptive Immunity --- Immunity --- Biological Factors --- Peptides --- Proteins --- Immune System Phenomena --- Amino Acids, Peptides, and Proteins --- Microbiology & Immunology --- Biology --- Health & Biological Sciences
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Cell therapy --- Cell transplantation --- Cells--Therapeutic use --- Cells--Transplantation --- Cellulaire therapie --- Cellulaire transplantatie --- Cellular therapy --- Cellular transplantation --- Cellules--Transplantation --- Celtherapie --- Celtransplantatie --- Therapie [Cellulaire ] --- Therapy [Cellular ] --- Thérapie cellulaire --- Transplantatie [Cel] --- Transplantation cellulaire --- Cloning --- Fetus --- Clonage --- Foetus --- Research --- Therapeutic use --- Recherche --- Emploi en thérapeutique --- therapeutisch kloneren (therapeutisch klonen) --- clonage thérapeutique (clonage humain thérapeutique) --- Thérapie cellulaire --- Emploi en thérapeutique --- Cellules souches embryonnaires --- Transplantation --- Clone cells
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The fifth volume in the essential series on stem cell biology provides a detailed explanation of the mechanisms of self-renewing cancer stem cells, as well as their ability to generate the heterogeneous lineages of cancer cells that comprise tumors. It explores the unique resistance of cancer stem cells to conventional chemotherapy techniques able to kill a tumor’s constituent cells. The contents also include a discussion of the myriad applications of a selection of stem cells in treating disease and tissue injury. The cells singled out include human mesenchymal, arterial, neural, cardiac, dental, limbal, and hematopoietic stem cells. The therapeutic utility of uniquely adaptable human embryonic stem cells, able to generate any human cell type, is explored in depth. The volume looks at their uses in tissue engineering and regenerative medicine, as well as pharmacological, toxicological, and cell differentiation research. It also sheds light on the processes by which embryonic stem cells begin to differentiate by aggregating into more complex embryoid bodies. With additional material on targeting self-renewal pathways in cancer stem cells, the use of mesenchymal stem cells in treating ischemic brain injury, and the phenomenon of neural stem cell proliferation around traumatic brain injuries, this richly diverse and hugely informative book is a powerful tool for deepening professional expertise among researchers and practitioners in this field.
Cancer cells. --- Stem cells -- Therapeutic use. --- Stem cells -- Transplantation. --- Medicine --- Biology --- Health & Biological Sciences --- Oncology --- Cytology --- Medicine. --- Cancer research. --- Gene expression. --- Laboratory medicine. --- Neurosciences. --- Oncology. --- Pathology. --- Biomedicine. --- Cancer Research. --- Gene Expression. --- Laboratory Medicine. --- Medical laboratories. --- Oncology . --- Tumors --- Diagnosis, Laboratory --- Health facilities --- Laboratories --- Disease (Pathology) --- Medical sciences --- Diseases --- Medicine, Preventive --- Neural sciences --- Neurological sciences --- Neuroscience --- Nervous system --- Genes --- Genetic regulation --- Expression --- Clinical medicine --- Clinical pathology --- Diagnostic laboratory tests --- Laboratory diagnosis --- Laboratory medicine --- Medical laboratory diagnosis --- Diagnosis --- Pathology --- Cancer research --- Stem cells.
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Progenitor and stem cells have the ability to renew themselves and change into a variety of specialised types, making them ideal materials for therapy and regenerative medicine. Progenitor and stem cell technologies and therapies reviews the range of progenitor and stem cells available and their therapeutic application.Part one reviews basic principles for the culture of stem cells before discussing technologies for particular cell types. These include human embryonic, induced pluripotent, amniotic and placental, cord and multipotent stem cells. Part two discusses wider issues such as
Cellular therapy. --- Stem cells -- Therapeutic use. --- Stem cells -- Transplantation. --- Stem cells --- Cellular therapy --- Bone Marrow Cells --- Stem Cells --- Cell Transplantation --- Hematopoietic System --- Cells --- Transplantation --- Hemic and Immune Systems --- Anatomy --- Surgical Procedures, Operative --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Hematopoietic Stem Cells --- Stem Cell Transplantation --- Biology --- Health & Biological Sciences --- Cytology --- Therapeutic use --- Therapeutic use. --- Transplantation. --- Cell therapy --- Therapy, Cellular --- Organotherapy --- Therapeutics, Physiological --- Transplantation of organs, tissues, etc. --- Cell transplantation --- Stem cell transplantation --- Colony-forming units (Cells) --- Mother cells --- Progenitor cells
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There are currently no reparative therapies for severe neurological injury, including brain injury, spinal cord injury and stroke. Actually, most treatments are designed simply to limit secondary damage. However, pre-clinical data supports the idea that exogenous stem and progenitor cells have the potential to promote a reparative response to severe neurological injuries. Progenitor Cell Therapy for Neurological Injury is a compilation of seminal essays that explore many unique aspects of neurological injury, focusing on the critical translational issues of cell delivery. Specifically, it discusses routes of administration, types of progenitor cells (alone and/or in combinations), timing of delivery and adjuncts to promote cell engraftment, survival and effectiveness. In addition, many chapters address measuring the effects of transplanted cells and cell tracking. The paradigms of how cell-based therapeutics affect neurological injury is changing rapidly. The developments in this field may ultimately offer realistic hope for improvement in patients with severe injuries. This book is a vital key toward unlocking those future treatments.
Brain -- Wounds and injuries -- Treatment. --- Medicine. --- Stem cells -- Therapeutic use. --- Stem cells --- Brain --- Cell Transplantation --- Diseases --- Transplantation --- Nervous System Diseases --- Stem Cell Transplantation --- Surgical Procedures, Operative --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Biology --- Health & Biological Sciences --- Cytology --- Pharmacy, Therapeutics, & Pharmacology --- Therapeutic use --- Wounds and injuries --- Treatment --- Cellular therapy. --- Nervous system --- Cell therapy --- Cells --- Therapy, Cellular --- Treatment. --- Life sciences. --- Stem cells. --- Life Sciences. --- Stem Cells. --- Organotherapy --- Therapeutics, Physiological --- Transplantation of organs, tissues, etc. --- Cell transplantation --- Colony-forming units (Cells) --- Mother cells --- Progenitor cells
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It is pointed out that cancer stem cell is a cell type within a tumor that possesses the capacity of cell-renewal and can give rise to the heterogeneous lineages of cancer cells that comprise the tumor. It is emphasized that a cancer stem cell is a tumor initiating cell. That conventional chemotherapy kills most cells in a tumor, but cancer stem cells remain intact is discussed. Vast applications of stem cells, cancer stem cells, mesenchymal stem cells, and human pluripotent stem cells are discussed. Because human embryonic stem cells possess the potential of producing unlimited quantities of any human cell type, considerable focus is placed on their therapeutic potential in this volume. Because of the pluripotency of embryonic stem cells, this volume discusses various applications such as tissue engineering, regenerative medicine, pharmacological and toxicological uses. The role of these cells in cell differentiation is also included. The role of cancer stem cells of breast, colon, and melanoma tumors in response to antitumor therapy is detailed. The role of cancer stem cells, specifically in the deadliest brain cancer, glioblastoma multiforme, is explained. Transplantation of bone marrow-derived stem cells for myocardial infarcation and use of mesenchymal stem cells in orthopedics are described.
Cancer cells. --- Medicine. --- Stem cells -- Therapeutic use. --- Stem cells -- Transplantation. --- Biology --- Medicine --- Health & Biological Sciences --- Cytology --- Oncology --- Stem cells --- Therapeutic use. --- Transplantation. --- Stem cell transplantation --- Colony-forming units (Cells) --- Mother cells --- Progenitor cells --- Cancer research. --- Pharmacology. --- Oncology. --- Stem cells. --- Apoptosis. --- Biomedicine. --- Cancer Research. --- Stem Cells. --- Pharmacology/Toxicology. --- Cells --- Pathology, Cellular --- Cell transplantation --- Oncology . --- Cytology. --- Toxicology. --- Tumors --- Chemicals --- Pharmacology --- Poisoning --- Poisons --- Cell biology --- Cellular biology --- Cytologists --- Toxicology --- Drug effects --- Medical pharmacology --- Medical sciences --- Chemotherapy --- Drugs --- Pharmacy --- Cell death --- Cancer research --- Physiological effect
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This fresh addition to the rapidly expanding Springer series on stem cells represents an additional forward step in our understanding of the causes, diagnosis, and cell-related therapies of major human diseases as well as debilitating injuries to human tissue and organs. Showcasing the work of more than 80 contributors from 13 nations, it offers an unrivalled breadth of differing perspectives on the subject, with dedicated sections covering umbilical cord, induced pluripotent, embryonic, and hematopoietic stem cells, in addition to stem cells in tumors and cancer, and the applications of stem cells in regenerative medicine. Enhanced by numerous color illustrations and tables that provide graphic clarification and summaries of key results, the volume succeeds in bringing together research results from oncologists, neurosurgeons, physicians, research scientists, and pathologists, whose accumulated wealth of practical experience will inform and inspire further developments in the vital and urgent work of cancer diagnosis, cure, and prevention.
Cancer cells. --- Stem cells -- Therapeutic use. --- Stem cells -- Transplantation. --- Medicine --- Health & Biological Sciences --- Oncology --- Stem cells. --- Colony-forming units (Cells) --- Mother cells --- Progenitor cells --- Medicine. --- Science. --- Cancer research. --- Biomedicine. --- Cancer Research. --- Biomedicine general. --- Medicine/Public Health, general. --- Science, general. --- Cells --- Pathology, Cellular --- Oncology. --- Science, Humanities and Social Sciences, multidisciplinary. --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Tumors --- Biomedicine, general. --- Health Workforce --- Cancer research
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