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The advancements in molecular marker discovery, genomics, transcriptomics and proteomics in recent years have enabled researchers to develop targeted therapies against cancers. Cancer research and management is multi-disciplinary and multimodal. In addition to conventional chemotherapy and radiotherapy, targeted immunotherapy has also provided considerable success in the clinic. There is also scientific evidence on the impact of alternative therapies on cancer patients. Modern Cancer Therapies and Traditional Medicine: An Integrative Approach to Combat Cancers summarizes the general aspects of cancer therapy and management. Chapters cover cancer medicine in two broad sections, the book presents comprehensive information on a diverse range of cancer treatments. The first section covers conventional molecular oncology and therapy including targeted therapies, immunotherapies, cancer signaling pathways and the use of computational techniques. The second section focuses on traditional methods of treatment including the role of nutrition, traditional medicine, Yoga and Ayurveda in cancer prevention and management. The book is an accessible update of the state of the art in cancer diagnostics and therapy for students and academicians at all levels.

Cancer--Alternative treatment.

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Growing numbers of cancer patients are exploring diet, food supplements, herbs, and nontoxic immunotherapies like bacterial vaccines as a means of therapy. Yet most cancer research organizations refuse to even evaluate these alternatives. Can Bacteria Cause Cancer? argues convincingly that unless this neglected world of alternative therapies is properly scrutinized, the medical Vietnam of the twentieth century may well affect one in two people by the twenty-first century. David J. Hess investigates one of the great medical mysteries of the twentieth century-the relationship between bacteria and chronic disease. Recently scientists have overturned long-held beliefs by demonstrating that bacterial infections cause many ulcers; they are now reconsidering the role of bacterial infections in other chronic diseases, such as arthritis. Is it possible, Hess asks, that bacteria can contribute to the many other known causes of cancer? To answer this intriguing question, Hess takes us into the world of alternative cancer researchers. Maintaining that their work has been actively suppressed rather than simply dismissed, he examines their claims--that bacterial vaccines have led to some dramatic cases of long-term cancer remission-and the scientific potential of their theories. Economic interests and cultural values, he demonstrates, have influenced the rush toward radiation and chemotherapy and the current cul-de-sac of toxic treatments. More than a medical mystery story, Can Bacteria Cause Cancer? is a dramatic case study of the failure of the war on cancer.

Bacterial diseases. --- Cancer -- Alternative treatment. --- Carcinogenesis. --- Cocarcinogenesis. --- Carcinogenesis --- Cocarcinogenesis --- Bacterial diseases --- Cancer --- Vertebrate Viruses --- Diseases --- Noxae --- Therapeutics --- Toxic Actions --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Viruses --- Chemical Actions and Uses --- Organisms --- Chemicals and Drugs --- Carcinogens --- Oncogenic Viruses --- Neoplasms --- Complementary Therapies --- Alternative treatment

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Management of advanced cancers by modern therapies can be hampered by the unavailability of efficient drugs, which explains in part the high mortality rates seen in patients with advanced cancers. Alternative therapies, particularly those using formulations derived from herbal, marine and animal products, are rich sources of chemically diverse and complex molecules with the potential to discover novel drugs. Alternative and Complementary Therapies for Cancer is unique in the field, as it presents the progress and limitations of alternative therapies through an unusual interface of traditional and modern concepts assembled by recognized experts (from China, India, USA, Canada, and Europe) in medical oncology, alternative medicine, cancer pharmacology and medicinal chemistry. Current developments from clinical and regulatory perspectives are presented, areas of controversy and potential integration of alternative and complementary therapies are highlighted, and future perspectives for the discovery of herbal constituents that may complement anticancer drugs are discussed.

Cancer -- Alternative treatment. --- Cancer --- Integrative medicine --- Therapeutics --- Diseases --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Complementary Therapies --- Neoplasms --- Medicine --- Health & Biological Sciences --- Oncology --- Alternative treatment --- Alternative medicine. --- Treatment. --- Complementary medicine --- Healing systems --- Systems, Healing --- Systems, Therapeutic --- Therapeutic systems --- Cancer therapy --- Cancer treatment --- Therapy --- Medicine. --- Pharmacology. --- Complementary medicine. --- Oncology. --- Medicine & Public Health. --- Medicine/Public Health, general. --- Complementary & Alternative Medicine. --- Pharmacology/Toxicology. --- Oncology  . --- Toxicology. --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Tumors --- Chemicals --- Pharmacology --- Poisoning --- Poisons --- Toxicology --- Health Workforce --- Drug effects --- Medical pharmacology --- Chemotherapy --- Drugs --- Pharmacy --- Physiological effect

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Natural products- compounds derived from plants, microbes and marine organisms, have been an unsurpassed source of cancer drugs in the modern era of drug discovery.  The historical record is strong, but what is the current impact of natural  products in the discovery and development of cancer drugs, and importantly what are the prospects for natural products to be a valuable source of  future agents?  This volume attempts to address this question through a series of chapters authored by leading researchers in the field which effectively provide an in-depth view of several high impact areas of natural products cancer research. The volume begins with a focused analysis and rationale for the clinical success  of current natural product anti-cancer drugs. The following chapters then describe new natural product based drugs in three rapidly evolving target classes and modalities- agents which target tumor vasculature, inhibitors of histone deacetylase and other histone modifying enzymes, and  antibody drug conjugates.  Subsequent chapters examine the central role of natural product chemical scaffolds in the genesis of new anti-cancer therapeutics- first via the powerful application of chemical synthesis, and then through the  rapidly emerging fields of biosynthetic engineering and plant cell culture.  The volume concludes with an assessment of the critical role that natural products continue to play in the search for new cancer drug targets.  As the reader makes his or her way through the volume it may become clear that there is strong evidence that natural products will continue to exert a profound positive impact on cancer drug discovery.

Cancer -- Adjuvant treatment. --- Cancer -- Alternative treatment. --- Cancer --- Drug development --- Natural products --- Chemistry, Pharmaceutical --- Therapeutic Uses --- Complex Mixtures --- Diseases --- Investigative Techniques --- Chemistry --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Chemicals and Drugs --- Pharmacology --- Pharmacologic Actions --- Natural Science Disciplines --- Biological Science Disciplines --- Chemical Actions and Uses --- Disciplines and Occupations --- Biological Products --- Drug Discovery --- Neoplasms --- Antineoplastic Agents --- Medicine --- Health & Biological Sciences --- Oncology --- Chemotherapy --- Research --- Drugs --- Drug development. --- Research. --- Design. --- Drug design --- Pharmaceutical design --- Development of drugs --- New drug development --- Pharmaceutical research --- Development --- Medicine. --- Cancer research. --- Pharmacology. --- Oncology. --- Biomedicine. --- Cancer Research. --- Pharmacology/Toxicology. --- Tumors --- Drug effects --- Medical pharmacology --- Medical sciences --- Chemicals --- Pharmacy --- Cancer research --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Pathology --- Physicians --- Physiological effect --- Oncology  . --- Toxicology. --- Poisoning --- Poisons --- Toxicology