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This volume is a practical guide of theranostics using intraoperative fluorescence imaging technology, as an all-out effort by the Japanese Society for Fluorescence Guided Surgery. It describes the various approaches the technique is being used such as vascular imaging, identification of lymphatic vessels by intratissue injection, lymph node imaging, and imaging for identification of anatomical structures. The book is organized into three major parts and the first one delivers the basics, introducing the use of the technology in clinical settings and initial setups. Next comes the description of clinical applications where chapters illustrate perfusion assessment, cancer localization, anatomy visualization, and lymph nodes/ducts mapping. Each chapter is devoted to the specific surgical field and disease areas, presenting images and videos of case studies. The last part presents some upcoming techniques for treatments. The Editor and the authors wish the ideas presented here will be hints to bridge the knowledge between surgeons and basic researchers for further innovation and practicality. It is important to stay up-to-date since intraoperative fluorescence imaging has been applied to clinical settings in various surgical fields and at the same time, novel techniques improving the efficacy of the technology have also been developed actively. Fluorescence-Guided Surgery – From Lab to Operation Room is recommended for surgeons, operating nurses, medical experts, basic researchers and, industry engineers worldwide beyond boundaries of specialties. Edited and written by experts of The Japanese Society for Fluorescence-Guided Surgery, those who are the founders of the technology, it describes the accurate development history and cutting-edge techniques based on the knowledge accumulated over the years. This is a translated version of the book originally published in Japanese language. This has been facilitated using machine translation (by the service DeepL.com) followed by authors revising, editing and verifying the translated manuscript.

Surgery. --- Endoscopic surgery. --- Cancer --- Oncology. --- Diseases. --- Anatomy. --- Minimally Invasive Surgery. --- Cancer Imaging. --- Imaging. --- Computer-assisted surgery.

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The twelfth volume in the “Interdisciplinary Cancer Research” series, titled “Head and Neck Cancers: An Interdisciplinary Approach,” offers comprehensive reviews on the diagnostic and treatment of head and neck cancers. It begins with an overview of interdisciplinary methods in this field. The book also delves into the role of the microbiome and the evolving understanding of virus-immune system interactions in head and neck cancer. Other chapters focus on circulating tumor cells, extracellular vesicles, and circulating non-coding RNAs. Additionally, it discusses novel therapeutic targets, including lipid levels, oxidative stress, antihypoxic agents, and senotherapy. This volume is part of the Cancer Immunology Project (CIP), part of the Universal Scientific Education and Research Network (USERN), and it is particularly valuable for researchers, head and neck oncosurgeons, and oncologists looking to expand their knowledge in this area.

Cancer. --- Cancer --- Oncology. --- Medical microbiology. --- Immunotherapy. --- Cancer Biology. --- Cancer Therapy. --- Medical Microbiology. --- Cancer Imaging. --- Treatment. --- Imaging.

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This book presents the rapidly developing field of artificial intelligence and machine learning and its application in biomedical imaging. As is known, starting from the diagnosis of fractures by using X-rays to understanding the complex structure and function of the brain, biomedical imaging has contributed immensely toward the development of precision diagnosis and treatment strategies for numerous diseases. While continuous evolution in imaging technologies have enabled the acquisition of images having resolution and contrast far better than ever, it significantly increased the volume of data associated with each image scan—making it increasingly difficult for experts to analyze and interpret. In this context, the application of artificial intelligence (AI) and machine learning (ML) tools has become one of the most exciting frontlines of contemporary research in biomedical imaging due to their capability to extract minute traces of various disease signatures from large and complicated datasets and providing clear insight into the potential abnormalities with excellent accuracy, sensitivity, and specificity. The hallmark of this book will be the contributions from international leaders on different AI-aided advanced biomedical imaging modalities and techniques. Included will be comprehensive description of several of the technology-driven spectacular advances made over the past few years that have allowed early detection and delineation of abnormalities with sub-pixel image segmentation and classification. Starting from the fundamentals of biomedical image processing, the book presents a streamlined and focused coverage of the core principles, theoretical and experimental approaches, and state-of-the-art applications of most of the currently used biomedical imaging techniques powered by AI.

Biophysics. --- Biomedical engineering. --- Optical spectroscopy. --- Cancer --- Bioanalysis and Bioimaging. --- Biomedical Engineering and Bioengineering. --- Optical Spectroscopy. --- Cancer Imaging. --- Imaging.

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Thepastdecadehasseendramaticadvances inurologyandimaging. Thesechangesareevident in improvements in laparoscopic surgery as well as in the emergence of multidetector CT, with multiplanar reformatting and FDG-PET-CT as routine imaging methods. The new minimally invasive procedures often require more exacting imaging as the surgeon does not have the same visual ?eld of view as was possible with open procedures. Thus, it is appropriate now to p- vide an update on imaging advances for the bene?t of urologists and radiologists alike. The increasing number of innovative imaging approaches to urologic tumors including CT, MRI, PET, SPECT, and endoscopic imaging can be perplexing and lead to over- and underesti- tions of the capabilities of modern imaging on the part of those who interpret them and those who use the information they provide for patient management. There is a growing “exp- tations gap” between what is expected and what is possible that needs to be closed. While previous books have focused on the more common urologic tumors such as bladder, prostate, andkidneycancer,nonehasattemptedacomprehensivereviewofthestateoftheartofimaging in most of the tumors involved in urologic oncology. Imaging in Urologic Oncology addresses these challenges. In the modern imaging department it is easy to forget how useful conventional plain rad- graphy can be in urologic diagnosis. Much of our current understanding of urologic disease is based on the “classic appearance” on intravenous urograms, cystograms, or retrograde pye- grams. Therefore, conventional imaging provides the ?rst “layer” in our understanding of u- logic tumors. The next layer is cross-sectional imaging.

Bladder -- Cancer -- Imaging. --- Kidneys -- Cancer -- Imaging. --- Prostate -- Cancer -- Imaging. --- Urogenital Neoplasms --- Diagnostic Imaging --- Male Urogenital Diseases --- Female Urogenital Diseases --- Diagnostic Techniques and Procedures --- Neoplasms by Site --- Diseases --- Neoplasms --- Diagnosis --- Female Urogenital Diseases and Pregnancy Complications --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Oncology --- Medicine --- Health & Biological Sciences --- Urology. --- Oncology. --- Medicine. --- Radiology. --- Medicine & Public Health. --- Imaging / Radiology. --- Tumors --- Genitourinary organs

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This book highlights the most efficient and latest ways to deal with cancer, focusing on IONPs. The book describes some well-designed surface modifications performed through several functional materials over the surface of IONPs, which results in the development of multifunctional IONPs-based delivery nanoplatforms by enhancing solubility, stability, and avoiding side effects on healthy cells. Several types of stimuli-responsive IONPs-based strategies are also discussed. Owing to magnetic, structural, and thermal properties, IONPs themselves can be utilized for magnetic targeting, magnetic hyperthermia, and phototherapy. Significant advancements are presented in IONPs-based immunotherapy, radiotherapy, and sonodynamic therapy for the efficient treatment of cancer. Finally, the book presents RIONs which serve as the parent platform for the development of powerful DMCAs utilized in SPECT/MRI and PET/MRI applications.

Medical physics. --- Cancer --- Nanochemistry. --- Nanotechnology. --- Biophysics. --- Medical Physics. --- Cancer Imaging. --- Nanoengineering. --- Bioanalysis and Bioimaging. --- Imaging. --- Nanoparticles. --- Treatment --- Technological innovations. --- Theranostic Nanomedicine. --- Neoplasms --- Magnetic Iron Oxide Nanoparticles. --- diagnostic imaging.