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Slave-trade --- Efik (African people). --- Calabar (Nigeria).

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History of Africa --- anno 1600-1699 --- anno 1700-1799 --- anno 1800-1899 --- Nigeria --- Calabar (Nigeria) --- Slave-trade --- Calabar, Nigeria --- Old Calabar (Nigeria) --- Economic conditions.

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"One of the earliest documents written by an African residing in coastal West Africa predating the arrival of British missionaries and officials in the mid-19th century. Antera Duke was a leader and merchant in late eighteenth-century Old Calabar. His diary is a candid account of daily life in an African community during a period of great historical interest"--Provided by publisher.

Slave traders --- Slave trade --- Slave dealers --- Slavers --- Traders, Slave --- Persons --- History --- Duke, Antera --- Old Calabar (Nigeria) --- Calabar (Nigeria) --- Enslavers

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Missions --- Missions --- Calabar (Nigeria) --- Jamaica --- Description and travel. --- Description and travel

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Investigations into Calabar beans (the dried ripe seeds of Physostigma venenosum) and their alkaloidal components compose a classical scientific journey throughout some one-and-a-half centuries and not only represent a fascinating aspect of the history of medicine but which is, moreover, still ongoing at the forefront of chemical and medical discovery. Those in particular involving its major such component, l-physostigmine, have led to an understanding of some of the fundamental mechanisms occurring in physiology, pharmacology and biochemistry and, either actually or potentially (by providing a template and thereby acting as a “lead compound”) have provided a useful treatment for a variety of neurological disorders associated with irregularities in cholinergic transmission in which augmentation of cholinergic activity has proved to be beneficial.

Botanical chemistry. --- Chemistry, Organic. --- Pharmaceutical chemistry. --- Plant Biochemistry. --- Organic Chemistry. --- Pharmaceutics. --- Chemistry, Medical and pharmaceutical --- Chemistry, Pharmaceutical --- Drug chemistry --- Drugs --- Medical chemistry --- Medicinal chemistry --- Pharmacochemistry --- Chemistry --- Organic chemistry --- Phytochemistry --- Plant biochemistry --- Plant chemistry --- Biochemistry --- Botany --- Phytochemicals --- Plant biochemical genetics --- Calabar bean --- Analysis. --- Ordeal bean --- Physostigma venenosum --- Beans