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The book 'Fused Pyranones: Multifaceted Building Blocks' delves into the chemistry of fused pyranones, particularly focusing on coumarins, chromones, and their derivatives. It serves as a comprehensive guide on the synthesis, chemical properties, and applications of these compounds in medicine and material science. The book highlights the significance of coumarins as versatile scaffolds for developing various heterocycles with wide-ranging applications, including medicinal drugs and industrial additives. It also outlines the advancements in synthetic methodologies, including catalytic and noncatalytic pathways. The book is intended for researchers and practitioners in the fields of chemistry and pharmaceutical sciences, offering an extensive review of the latest literature and research developments in the study of natural and synthetic coumarins and chromones.
Coumarins. --- Heterocyclic chemistry. --- Coumarins --- Heterocyclic chemistry
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Advances in Structure and Activity Relationship of Coumarin Derivatives covers the structural behavior of various coumarin derivatives for various potential pharmaceutical applications. Based on substitution targeted for active sites, the book takes a rational approach for designing new and specific potent drugs, optimizing existing ones, and developing novel reactions. This focused primer describes the chemical structure and activity of coumarin derivatives to explore the effects of different substituents at specific positions, and their properties for effective bioactivity.
Coumarins. --- Coumarins --- Derivatives. --- Benzopyranones --- Benzopyrones --- Coumarines --- Cumarins --- Benzopyrans
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PLANTS, MEDICINAL --- FLAVONES --- QUERCETIN --- COUMARINS --- BIOFLAVONOIDS --- PLANT EXTRACTS
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Coumarins --- Plants, Medicinal --- Molecular Structure --- isolation & purification --- Molecular structure. --- Plants --- Isolation and purification. --- Medicinal --- Analysis.
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Coumarins --- Coumarines --- Pharmacokinetics --- Therapeutic use --- Emploi en thérapeutique. --- Pharmacocinétique. --- Emploi en thérapeutique. --- Pharmacocinétique.
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The available parenteral and oral anticoagulants have a large clinical use. Understanding biochemistry of anticoagulants may help to improve therapeutic strategies. Resistance to vitamin K antagonist drugs might be a problem for rodent populations. Patients who have thrombogenic risk factors should be anticoagulated. The need for cardiac implantable electronic devices is increasing, and there is a substantial number of patients who are on oral anticoagulant therapy. Prothrombin complex concentrate and other plasma concentrates are useful to deal with over-coagulated situations. The efficacy and safety of non-vitamin K antagonist oral anticoagulants have been proven in large phase III trials. The real-world data suggest even better outcomes with these agents compared to vitamin K antagonists.
Anticoagulants (Medicine) --- Warfarin. --- Coumadin (Trademark) --- Coumarins --- Rodenticides --- Antithrombotic agents --- Blood thinners --- Blood thinning drugs --- Hematologic agents --- Blood --- Coagulation --- Pharmacology
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Warfarin. --- Drug monitoring. --- Drugs --- Monitoring, Drug --- Therapeutic drug monitoring --- Patient monitoring --- Coumadin (Trademark) --- Anticoagulants (Medicine) --- Coumarins --- Rodenticides --- Monitoring --- Analysis --- Testing
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COUMARINS --- FLAVONOIDS --- ACETYLENES --- FRUIT DEVELOPMENT --- ETHNOBOTANY --- CHEMOTAXONOMY --- COMPARATIVE ANATOMY --- STOMATA --- CYTOGENETICS --- POLLEN --- FLOWERS --- TAXONOMY --- APIACEAE --- CHEMISTRY --- MORPHOLOGY --- BIOLOGY
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The volumes of this classic series, now referred to simply as "Zechmeister" after its founder, L. Zechmeister, have appeared under the Springer Imprint ever since the series' inauguration in 1938. The volumes contain contributions on various topics related to the origin, distribution, chemistry, synthesis, biochemistry, function or use of various classes of naturally occurring substances ranging from small molecules to biopolymers. Each contribution is written by a recognized authority in his field and provides a comprehensive and up-to-date review of the topic in question. Addressed to biologists, technologists, and chemists alike, the series can be used by the expert as a source of information and literature citations and by the non-expert as a means of orientation in a rapidly developing discipline.
Chemistry. --- Organic Chemistry. --- Chemistry, Organic. --- Chimie --- Chimie organique --- Anticoagulants (Medicine). --- Coumarins. --- Biochemistry --- Chemistry --- Physical Sciences & Mathematics --- Organic compounds. --- Compounds, Organic --- Organic chemicals --- Organic chemistry --- Organic chemistry. --- Carbon compounds
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