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Mit der Motivation, einen strömungsmechanischen Beitrag zur Planung und Bewertung von Herzoperationen zu leisten, wurde am Institut für Strömungslehre das Karlsruhe Heart Model (KaHMo) entwickelt. Ziel dieser Arbeit war die abschließende Entwicklung des KaHMo-MRT hin zu einem einsatzfähigen Modell für die klinische Anwendung. Im Fokus standen hierbei die Modellierung des Vorhofs sowie die Validierung der linken Herzkammer.

CFD --- patientenspezifisch --- Vorhof --- virtuelles Herz --- Validierung

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The characteristic vortex formation in the ventricles is believed to be affected at an early stage of heart diseases. First, post-processing of patient-specific data has to be standardised. The chosen methods, a combination of Eulerian and Lagrangian techniques, are characterised by means of necessary spatial and temporal resolutions. Second, the goal is to find the best cost-benefit approach for modelling of the mitral valve, as it affects vortex formation and progression in the left ventricle.

CFD --- vortex identification --- mitral valve --- WIrbelidentifikation --- Mitralklappe

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The Smoothed Particle Hydrodynamics (SPH) method is proposed for studying hydrodynamic processes related to nuclear engineering problems. A problem of possible recriticality due to the sloshing motions of the molten reactor core is studied with SPH method. The accuracy of the numerical solution obtained in this study with the SPH method is significantly higher than that obtained with the SIMMER-III/IV reactor safety analysis code.

CFD --- Sloshing --- Recriticality --- SPH --- Free Surface Flows

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The Smoothed Particle Hydrodynamics (SPH) method is proposed for studying hydrodynamic processes related to nuclear engineering problems. A problem of possible recriticality due to the sloshing motions of the molten reactor core is studied with SPH method. The accuracy of the numerical solution obtained in this study with the SPH method is significantly higher than that obtained with the SIMMER-III/IV reactor safety analysis code.

CFD --- Sloshing --- Recriticality --- SPH --- Free Surface Flows --- CFD --- Sloshing --- Recriticality --- SPH --- Free Surface Flows

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A multiscale simulation model is developed by combining the CFD Simulation and the population balance equations to describe a transient process of fluidized bed spray granulation. In this model, the CFD simulation generates the particle growth and nucleation rates in consideration of fluid dynamics, drying and multiple interactions, such as drops deposition, dust integration and nucleation between different particles (drops, dust and granules).

CFD-Simulation --- Keimbildungsrate --- Partikel-Populationsbilanzen --- Wirbelschicht-Sprühgranulation --- Multiscale-Simulation