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Camptothecin and camptothecin producing plants : botany, chemistry, anticancer activity and biotechnology
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ISBN: 9780128209271 0128209275 9780128204993 0128204990 Year: 2020 Publisher: London, United Kingdom : Academic Press, an imprint of Elsevier,

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Camptothecin.

The camptothecins : unfolding their anticancer potential
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ISBN: 1573312924 Year: 2000 Volume: 922 Publisher: New York New York Academy of Sciences

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Camptothecin and camptothecin producing plants
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ISBN: 0128209275 0128204990 9780128209271 9780128204993 Year: 2020 Publisher: London Academic Press

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The camptothecins : from discovery to the patient
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ISBN: 1573310565 1573310573 Year: 1996 Volume: 803

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Dissertation
Clinical pharmacokinetics and pharmacodynamics of anticancer agents : focus on carboplatin and topotecan
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ISBN: 9039306885 Year: 1995 Publisher: Utrecht Universiteit Utrecht

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New drug therapy
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Year: 1994 Publisher: London : W.B. Saunders,

Camptothecins in Cancer Therapy
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ISBN: 9781588290274 1588290271 9781592598663 9786610359509 1280359501 1592598668 1627038167 Year: 2005 Publisher: Totowa, NJ : Humana Press : Imprint: Humana,

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Clinical interest in the camptothecins continues to expand even though this class of topoisomerase I inhibitors has been studied for almost 50 years, and two early generation members of the family have gained FDA approval. In Camptothecins in Cancer Therapy, leading clinicians and researchers critically review our current understanding of camptothecins, their shortcomings, and the possibilities for improving their clinical performance. The authors discuss new camptothecin analog development, drug delivery issues for optimizing their anticancer activity, and their potential use in a variety of different cancers. Additional chapters describe what is known about the biochemistry, the pharmacology, and the chemistry of the camptothecins, including the mechanism of topoisomerase and how camptothecins poison this enzyme, the use of animal models in defining the anticancer potential of camptothecins, and the question of camptothecin resistance. Authoritative and up-to-date, Camptothecins in Cancer Therapy provides a comprehensive summary of camptothecin research, as well as a much-needed guide to all the latest information on their optimal therapeutic applications.


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Carbon Nanomaterials for Therapy, Diagnosis, and Biosensing
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Year: 2022 Publisher: Basel MDPI - Multidisciplinary Digital Publishing Institute

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In the landscape of the design of carbon nanomaterials, the fine-tuning of their functionalities and physico-chemical properties has increased their potential for therapeutic, diagnostic, and biosensing applications. In this editorial, we will provide a brief overview of the contents of this Special Issue. In particular, nanoplatforms originating from the synergistic combination of carbon-based nanomaterials (i.e., nanotubes, graphene, graphene oxide, carbon quantum dots, nanodiamond, etc.) with various functional molecules such as drugs, natural compounds, biomolecules, polymers, metal nanoparticles, and macrocycles that have useful applications in drug delivery, multi-targeted therapies, theranostic as well as scaffolds in tissue engineering, and as sensing materials have been selected for publication as Articles or Mini Reviews. The variety of applications covered by the nine articles published in this Special Issue of Nanomaterials are proof of the growing attention that the use of carbon nanomaterials in the biomedical/pharmaceutical field has received in recent years. We hope that readers find the contents of this Special Issue useful for their research, which is aimed to advance carbon nanomaterials from the laboratory to clinical nanomedicine.


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Nucleic Acids Conjugates for Biotechnological Applications
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Year: 2021 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

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Life in biological systems is maintained by the cooperative actions of various biomolecules. With the development of chemical and biological technologies related to nucleic acids, the details of the mechanisms of such cooperative actions between nucleic acids and other biomolecules have been elucidated and further applied in various applications. In the papers published in this Special Issue, advanced research works involved in nucleic acid conjugates are reported in wide application fields, such as artificial gene regulation, biomolecular sensing, and therapeutics from leading scientists in nucleic acids chemistry and engineering.


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Carbon Nanomaterials for Therapy, Diagnosis, and Biosensing
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Year: 2022 Publisher: Basel MDPI - Multidisciplinary Digital Publishing Institute

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Abstract

In the landscape of the design of carbon nanomaterials, the fine-tuning of their functionalities and physico-chemical properties has increased their potential for therapeutic, diagnostic, and biosensing applications. In this editorial, we will provide a brief overview of the contents of this Special Issue. In particular, nanoplatforms originating from the synergistic combination of carbon-based nanomaterials (i.e., nanotubes, graphene, graphene oxide, carbon quantum dots, nanodiamond, etc.) with various functional molecules such as drugs, natural compounds, biomolecules, polymers, metal nanoparticles, and macrocycles that have useful applications in drug delivery, multi-targeted therapies, theranostic as well as scaffolds in tissue engineering, and as sensing materials have been selected for publication as Articles or Mini Reviews. The variety of applications covered by the nine articles published in this Special Issue of Nanomaterials are proof of the growing attention that the use of carbon nanomaterials in the biomedical/pharmaceutical field has received in recent years. We hope that readers find the contents of this Special Issue useful for their research, which is aimed to advance carbon nanomaterials from the laboratory to clinical nanomedicine.

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