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Hormonal influences, both natural and iatrogenic, are implicated in the most frequent health issues of women. Endometrial cancer is now the most common gynecologic cancer in the United States and the industrialized world. This cancer is strongly related to hormonal and metabolic factors. In addition, breast cancer treated with hormone therapy (Tamoxifen) may, in some cases, be associated with uterine pathology. Hormone therapy is used to improve the physiological effects and counteract abnormal and deleterious effects of “natural” hormonal activity. Millions of women receive hormone therapy at some point of their life: using oral contraceptives, reproductive technology, treatment for post-menopausal symptoms, among other uses. This book addresses a range of women’s health issues, from fertility to neoplasms, and their relationship with natural and iatrogenic hormonal effects. Chapters include clinical and pathological descriptions, theoretical and practical medical issues, and original studies and cases. Controversial issues in certain hormone therapies are presented with updated concepts based on clinical studies and novel statistical methods. The book will be useful for specialized and general physicians, oncologists, endocrinologists, researchers, medical students, and others in the field of women’s health. .

Cancer research. --- Endocrinology . --- Pathology. --- Cancer Research. --- Endocrinology. --- Disease (Pathology) --- Medical sciences --- Diseases --- Medicine --- Medicine, Preventive --- Internal medicine --- Hormones --- Cancer research --- Uterus --- Diseases. --- Uterine diseases --- Endometri --- Càncer d'úter --- Càncer de matriu --- Càncer uterí --- Malalties uterines --- Càncer d'endometri --- Càncer de coll uterí --- Endometrium --- Mucosa uterina --- Membrana mucosa --- Úter --- Endometriosi --- Secreció --- Histamina --- Hormones esteroides --- Hormones gastrointestinals --- Hormones juvenils --- Hormones peptídiques --- Hormones pituïtàries --- Hormones tiroides --- Melatonina --- Catecolamines --- Endocrinologia --- Glàndules endocrines --- Cancer. --- Cancer Biology. --- Cancers --- Carcinoma --- Malignancy (Cancer) --- Malignant tumors --- Tumors

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This book summarizes the important developments in the field of cancer research, specifically uterine cervical/endometrial cancer and ovarian cancer. It highlights the recent advances in gynecologic cancer, such as next generation models of genetically engineered animal models or cancer cell lines, focusing on their significance for advancing our understanding of gynecologic cancer biology, prevention and treatment, and drug response and resistance. Cancer research in the area of gynecologic tumors has undergone an enormous transformation over the past decade, with a greater understanding of tumor biology, elucidation of novel targets for therapeutic intervention, and better recognition of genetic predisposition syndromes. At the same time, the recent advances in basic cancer research have provided key insights into all aspects of gynecologic cancer biology, including developmental pathways and the impact of lineage plasticity, understanding metastatic progression, uncovering the roles of the tumor microenvironment , exploring tumor evolution, and discovering new therapeutic approaches and mechanisms of drug sensitivity and adaptive response. Molecular Diagnosis and Targeting for Gynecologic Malignancy appeals to investigators, clinicians, residents and postdocs who are curious about new research on gynecologic malignancies. It not only presents basic and translational research, but also explores the generalizability of the evidence covering the interface between basic and clinical science. Furthermore, a number of the topics offer the basis for new ideas that have the potential to advance into the gynecologic malignancies. This book provides readers with state-of-the-art information that will help improve the lives of patients with these challenging diseases.

Oncology  . --- Gynecology . --- Cancer research. --- Cell biology. --- Oncology. --- Gynecology. --- Cancer Research. --- Cell Biology. --- Cell biology --- Cellular biology --- Biology --- Cells --- Cancer research --- Gynaecology --- Medicine --- Generative organs, Female --- Tumors --- Diseases --- Cancer. --- Gynecologic cancer --- Cancer in women --- Genital Neoplasms, Female. --- Ovarian Neoplasms. --- Uterine Cervical Neoplasms. --- Cancer of Cervix --- Cancer of the Cervix --- Cancer of the Uterine Cervix --- Cervical Cancer --- Cervical Neoplasms --- Cervix Cancer --- Cervix Neoplasms --- Neoplasms, Cervical --- Neoplasms, Cervix --- Uterine Cervical Cancer --- Cancer, Cervix --- Cancer, Uterine Cervical --- Cancers, Cervix --- Cancers, Uterine Cervical --- Cervical Cancer, Uterine --- Cervical Cancers, Uterine --- Cervical Neoplasm --- Cervical Neoplasm, Uterine --- Cervical Neoplasms, Uterine --- Cervix Neoplasm --- Neoplasm, Cervical --- Neoplasm, Cervix --- Neoplasm, Uterine Cervical --- Neoplasms, Uterine Cervical --- Uterine Cervical Cancers --- Uterine Cervical Neoplasm --- Uterine Cervical Dysplasia --- Cervical Intraepithelial Neoplasia --- Cancer of the Ovary --- Neoplasms, Ovarian --- Ovary Cancer --- Ovary Neoplasms --- Cancer of Ovary --- Ovarian Cancer --- Cancer, Ovarian --- Cancer, Ovary --- Cancers, Ovarian --- Cancers, Ovary --- Neoplasm, Ovarian --- Neoplasm, Ovary --- Neoplasms, Ovary --- Ovarian Cancers --- Ovarian Neoplasm --- Ovary Cancers --- Ovary Neoplasm --- Germinoma --- Female Genital Neoplasms --- Neoplasms, Female Genital --- Neoplasms, Gynecologic --- Gynecologic Neoplasms --- Female Genital Neoplasm --- Genital Neoplasm, Female --- Gynecologic Neoplasm --- Neoplasm, Female Genital --- Neoplasm, Gynecologic --- Cancer, Cervical --- Cervical Cancers --- Càncer --- Malalties de l'aparell genital femení --- Càncer d'ovari --- Càncer d'úter --- Càncer de matriu --- Càncer uterí --- Malalties uterines --- Càncer d'endometri --- Càncer de coll uterí --- Càncer d'ovaris --- Malalties ginecològiques --- Malalties de l'aparell genital --- Endometriosi --- Fibromiomes uterins --- Malalties de la vagina --- Malalties de la vulva --- Malalties de les trompes de Fal·lopi --- Malalties de l'ovari --- Ginecologia --- Carcinoma --- Carcinosi --- Càncer d'ossos --- Càncer de cap --- Càncer de coll --- Càncer de bufeta --- Càncer de fetge --- Càncer de laringe --- Càncer de mama --- Càncer de pàncrees --- Càncer de pell --- Càncer de pròstata --- Càncer de pulmó --- Càncer de ronyó --- Càncer de tiroide --- Càncer gastrointestinal --- Càncer ginecològic --- Càncer en els adolescents --- Càncer en els infants --- Medicaments antineoplàstics --- Melanoma --- Leucèmia --- Sarcoma --- Carcinògens --- Cèl·lules canceroses --- Cirurgia oncològica --- Infermeria oncològica --- Malalts de càncer --- Metàstasi --- Oncologia