Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

This highly informative and clearly written book presents the basic science and the latest data on hereditary breast and ovarian cancer (HBOC) to provide an up-to-date and holistic overview of the disease. It starts off by presenting the molecular mechanisms, genetic testing and counseling, and variants of unknown significance (VUS) to help readers understand the contemporary interpretation of the disease. Further chapters focus on the surveillance, diagnosis and treatment, including chemoprevention, risk reduction and drug development based on molecular mechanisms. It also includes a chapter on the latest findings from the HBOC database, ethical issues and the parp inhibitors, and discusses innovative thinking to manage and understand the disease. Hereditary Breast and Ovarian Cancer - Molecular Mechanism and Clinical Practice offers breast surgeons, medical oncologists, gynecological oncologists and genetic counselors a comprehensive overview of the disease. Providing insights into recent scientific findings and further avenues for investigation, it is also a thought-provoking and informative read for researchers and scholars.

Breast --- Ovaries --- Breast Neoplasms --- Neoplasms --- Ovarian Neoplasms --- Cancer --- Genetic aspects. --- Molecular aspects. --- genetics. --- diagnosis. --- Càncer d'ovari --- Càncer de mama --- Genètica molecular humana --- Antropologia molecular --- Genètica humana --- Genètica molecular --- Càncer de pit --- Càncer --- Malalties de la mama --- Càncer ginecològic --- Càncer d'ovaris --- Internal medicine. --- Surgery. --- Medicine --- Biology --- Medical genetics. --- Internal Medicine. --- Biomedical Research. --- Medical Genetics. --- Research. --- Clinical genetics --- Diseases --- Heredity of disease --- Human genetics --- Medical sciences --- Pathology --- Genetic disorders --- Biological research --- Biomedical research --- Health Workforce --- Surgery, Primitive --- Medicine, Internal --- Genetic aspects

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

This book summarizes the important developments in the field of cancer research, specifically uterine cervical/endometrial cancer and ovarian cancer. It highlights the recent advances in gynecologic cancer, such as next generation models of genetically engineered animal models or cancer cell lines, focusing on their significance for advancing our understanding of gynecologic cancer biology, prevention and treatment, and drug response and resistance. Cancer research in the area of gynecologic tumors has undergone an enormous transformation over the past decade, with a greater understanding of tumor biology, elucidation of novel targets for therapeutic intervention, and better recognition of genetic predisposition syndromes. At the same time, the recent advances in basic cancer research have provided key insights into all aspects of gynecologic cancer biology, including developmental pathways and the impact of lineage plasticity, understanding metastatic progression, uncovering the roles of the tumor microenvironment , exploring tumor evolution, and discovering new therapeutic approaches and mechanisms of drug sensitivity and adaptive response. Molecular Diagnosis and Targeting for Gynecologic Malignancy appeals to investigators, clinicians, residents and postdocs who are curious about new research on gynecologic malignancies. It not only presents basic and translational research, but also explores the generalizability of the evidence covering the interface between basic and clinical science. Furthermore, a number of the topics offer the basis for new ideas that have the potential to advance into the gynecologic malignancies. This book provides readers with state-of-the-art information that will help improve the lives of patients with these challenging diseases.

Oncology  . --- Gynecology . --- Cancer research. --- Cell biology. --- Oncology. --- Gynecology. --- Cancer Research. --- Cell Biology. --- Cell biology --- Cellular biology --- Biology --- Cells --- Cancer research --- Gynaecology --- Medicine --- Generative organs, Female --- Tumors --- Diseases --- Cancer. --- Gynecologic cancer --- Cancer in women --- Genital Neoplasms, Female. --- Ovarian Neoplasms. --- Uterine Cervical Neoplasms. --- Cancer of Cervix --- Cancer of the Cervix --- Cancer of the Uterine Cervix --- Cervical Cancer --- Cervical Neoplasms --- Cervix Cancer --- Cervix Neoplasms --- Neoplasms, Cervical --- Neoplasms, Cervix --- Uterine Cervical Cancer --- Cancer, Cervix --- Cancer, Uterine Cervical --- Cancers, Cervix --- Cancers, Uterine Cervical --- Cervical Cancer, Uterine --- Cervical Cancers, Uterine --- Cervical Neoplasm --- Cervical Neoplasm, Uterine --- Cervical Neoplasms, Uterine --- Cervix Neoplasm --- Neoplasm, Cervical --- Neoplasm, Cervix --- Neoplasm, Uterine Cervical --- Neoplasms, Uterine Cervical --- Uterine Cervical Cancers --- Uterine Cervical Neoplasm --- Uterine Cervical Dysplasia --- Cervical Intraepithelial Neoplasia --- Cancer of the Ovary --- Neoplasms, Ovarian --- Ovary Cancer --- Ovary Neoplasms --- Cancer of Ovary --- Ovarian Cancer --- Cancer, Ovarian --- Cancer, Ovary --- Cancers, Ovarian --- Cancers, Ovary --- Neoplasm, Ovarian --- Neoplasm, Ovary --- Neoplasms, Ovary --- Ovarian Cancers --- Ovarian Neoplasm --- Ovary Cancers --- Ovary Neoplasm --- Germinoma --- Female Genital Neoplasms --- Neoplasms, Female Genital --- Neoplasms, Gynecologic --- Gynecologic Neoplasms --- Female Genital Neoplasm --- Genital Neoplasm, Female --- Gynecologic Neoplasm --- Neoplasm, Female Genital --- Neoplasm, Gynecologic --- Cancer, Cervical --- Cervical Cancers --- Càncer --- Malalties de l'aparell genital femení --- Càncer d'ovari --- Càncer d'úter --- Càncer de matriu --- Càncer uterí --- Malalties uterines --- Càncer d'endometri --- Càncer de coll uterí --- Càncer d'ovaris --- Malalties ginecològiques --- Malalties de l'aparell genital --- Endometriosi --- Fibromiomes uterins --- Malalties de la vagina --- Malalties de la vulva --- Malalties de les trompes de Fal·lopi --- Malalties de l'ovari --- Ginecologia --- Carcinoma --- Carcinosi --- Càncer d'ossos --- Càncer de cap --- Càncer de coll --- Càncer de bufeta --- Càncer de fetge --- Càncer de laringe --- Càncer de mama --- Càncer de pàncrees --- Càncer de pell --- Càncer de pròstata --- Càncer de pulmó --- Càncer de ronyó --- Càncer de tiroide --- Càncer gastrointestinal --- Càncer ginecològic --- Càncer en els adolescents --- Càncer en els infants --- Medicaments antineoplàstics --- Melanoma --- Leucèmia --- Sarcoma --- Carcinògens --- Cèl·lules canceroses --- Cirurgia oncològica --- Infermeria oncològica --- Malalts de càncer --- Metàstasi --- Oncologia