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Chondrosarcoma : biology and clinical management
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ISBN: 3030745724 3030745716 Year: 2021 Publisher: Cham, Switzerland : Springer,

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Chordoma of the Spine : A Comprehensive Review
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ISBN: 3030762017 3030762009 Year: 2021 Publisher: Cham : Springer International Publishing : Imprint: Springer,

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This book provides a comprehensive review of the epidemiology, pathogenesis, diagnosis, and management of chordomas of the mobile spine and sacrum. Historically, knowledge about how to deliver such state-of-the-art care has not been widespread, resulting in inconsistent treatment, and, all too often, suboptimal outcomes for chordoma patients. This text is an important step towards broadening that knowledge, and, in turn, improving the care provided to chordoma patients. The book is divided into 4 parts comprising 16 chapters. The first part focuses on the pathophysiology and molecular drivers of chordoma. The second focuses on the epidemiology and clinical history, as well as the histological, oncologic, and radiographic work-up of chordoma. The third part focuses primarily on the technical aspects of surgery for chordoma. It is broken down by anatomic region, with the final two chapters focusing on the soft tissue and bony reconstruction following chordoma resection. The last part focuses on the exciting field of adjuvant therapies for chordoma. This includes both radiation therapies and novel chemotherapeutic options for recurrent, metastatic, and dedifferentiated chordoma. Written by world experts from leading chordoma centers, Chordoma of the Spine serves as a valuable reference for spinal oncologists and general spine surgeons who may encounter chordoma patients in their practice. It provides the most up-to-date evidence regarding all aspects of treating patients with this disease. By focusing on this specific pathology of the spine, this resource condenses expert-level research into understandable treatment algorithms.


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Bone tumors : diagnosis and therapy today
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ISBN: 1447175018 1447174992 Year: 2021 Publisher: London : Springer,

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Surgery of pelvic bone tumors
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ISBN: 3030770079 3030770060 Year: 2021 Publisher: Cham, Switzerland : Springer,

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Current Advances in the Science of Osteosarcoma : Research Perspectives: Tumor Biology, Organ Microenvironment, Potential New Therapeutic Targets, and Canine Models
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ISBN: 3030430855 3030430847 Year: 2020 Publisher: Cham : Springer International Publishing : Imprint: Springer,

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This thoroughly revised second edition is an up-to-date overview of the new advances in the knowledge of the basic science in sarcoma and osteosarcoma. It features detailed, in-depth discussions of microRNAs in osteosarcoma, historical perspectives of chemotherapy in the treatment of the disease, tumor targeted IL12 therapy and HER2 targeted therapy, the role of enhancer elements in regulating the prometastatic transcriptional program and more. Further, this essential volume also includes new insights on Wnt signaling in osteosarcoma, the role of genomics, genetically modified T-cell therapy, liquid biopsy, oncolytic viruses, immunophenotyping, receptor tyrosine kinases and epigenetic-focused approaches for treatment of osteosarcoma metastases, as well as thoughts on the current standard of treatment for patients suffering from these cancers. In the years since the previous edition, there have been numerous new developments in this rapidly changing field; this new edition is both timely and urgently needed. When taken together these companion volumes, Current Clinical (Book 1) and Scientific (Book 2) Advances in Osteosarcoma, are a timely and urgently needed guide for laboratory investigators and clinical oncologists.


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Rehabilitation after limb salvage surgery
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ISBN: 3030663523 3030663515 Year: 2021 Publisher: Cham, Switzerland : Springer,

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Based on ten years of experience, this book provides a valuable tool for professionals in the field of bone tumors. Although rare, when diagnosed these tumors can cause anxiety and apprehension in patients, and it is necessary to find rapid solutions and medical rehabilitation protocols capable of dealing with these delicate cases. As such those working in this field need to constantly update their knowledge to ensure an appropriate approach to this particular pathology. This book is a useful consultation tool for physiotherapists, orthopedic oncology surgeons, rehabilitation specialists and everyone who works with bone tumors on a regular basis.


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Herbs for Cancer Treatment
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ISBN: 9813291478 981329146X Year: 2019 Publisher: Singapore : Springer Singapore : Imprint: Springer,

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This book provides detailed information on the various types of cancer, etiology, effects, and challenges associated with current cancer treatment regimes. The present edition has been written to reflect recent developments, success rates and lacunae in herbal and modern cancer therapies. It also describes the use of several herbal formulations to boost patients’ immunity, in order to prevent or help them cope with several cancers. The book highlights several herbs/shrubs/trees that have been reported to possess anti-cancer properties, paving the way for in-depth research into the dose standardization and efficacy of plant-based bioactive molecules. It also focuses on the sustainable conservation of medicinal flora, so that, in future, novel biomolecules be extracted and made available for the treatment of various cancers. Given its highly relevant content, the book will benefit the entire cancer research community (students, scientists, pharmacists, herbalists and lecturers) at universities, research institutions and industry in the areas of oncology, herbal cancer therapy, biotechnology, drug discovery, pharmaceuticals, agriculture, and various disciplines of the biomedical sciences.


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Nasopharyngeal cancer : a practical guide on diagnosis and treatment
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ISBN: 3030650375 3030650367 Year: 2021 Publisher: Cham, Switzerland : Springer,

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This book provides up-to-date guidance that will assist radiation oncologists during the day-to-day management of nasopharyngeal cancer. After discussion of diagnosis and staging, target delineation techniques and treatment planning are described for both intensity-modulated and particle radiation therapy. Detailed information is then presented on the application of radiation therapy in different disease settings, from early stage disease to metastatic disease. Due attention is paid to the role of multimodality treatment and new and advanced technologies in particular circumstances, such as local recurrence. In addition, follow-up and the management of late toxicities are explained and management strategies are documented for special situations and groups, including pediatric patients. The book is published within the Springer series Practical Guides in Radiation Oncology. Like other volumes in the series, it is designed for hands-on use by both radiation oncology residents and practicing radiation oncologists. It will also be of value for head and neck physicians.


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Imaging of bone tumors in shoulder and elbow
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ISBN: 9813361506 9813361492 Year: 2021 Publisher: Singapore : Springer : Peking Union Medical College Press,

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This book provides a detailed description of typical imaging features of bone tumors and tumor-like lesions in the shoulder and elbow. Each chapter deals with one major bone tumor or tumor-like lesions, for example, giant cell tumor, bone cyst, osteochondroma, chondrosarcoma, Ewing sarcoma, bone metastases, lymphoma, etc. Typical cases are carefully selected from thousands of clinical cases accompanying with comprehensive imaging information of X-ray, CT and MRI. In-depth analysis and differential diagnostic tips from experienced bone tumor specialists is presented at the end of each case. This book will be useful and worthy to musculoskeletal radiologists, orthopaedic surgeons, general radiologists, and oncologists.

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